Laboratory diagnosis and potential application of nucleic acid biosensor approach for early detection of dengue virus infections
Dengue fever is caused by the dengue virus, the genus of Flaviviridae virus family. Until now, there is no specific medication to kill the dengue virus and patients just solely depend on the treatment of the dengue infection symptoms. Thus, a highly sensitive and rapid diagnostic tool for early diag...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Oriental Scientific Publishing Company
2018
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| Online Access: | http://psasir.upm.edu.my/id/eprint/74813/ http://psasir.upm.edu.my/id/eprint/74813/1/Laboratory%20diagnosis%20and%20potential%20application%20of%20nucleic%20acid%20biosensor%20approach%20for%20early%20detection%20of%20dengue%20virus%20infections.pdf |
| _version_ | 1848857557869789184 |
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| author | Abdul Rashid, Jahwarhar Izuan Yusof, Nor Azah |
| author_facet | Abdul Rashid, Jahwarhar Izuan Yusof, Nor Azah |
| author_sort | Abdul Rashid, Jahwarhar Izuan |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Dengue fever is caused by the dengue virus, the genus of Flaviviridae virus family. Until now, there is no specific medication to kill the dengue virus and patients just solely depend on the treatment of the dengue infection symptoms. Thus, a highly sensitive and rapid diagnostic tool for early diagnosis of dengue virus is very desirable, especially in resource limited-condition. We briefly review pro and cons of existing diagnostic methods for the detection of dengue virus (virus isolation, PCR, NS1Ag, Serology). We also highlight the recent advances of the biosensor technology in the dengue diagnostic dengue as a promising point-of-care diagnostic in the future. The DNA based biosensor technology combined miniaturized sample preparation offers a good opportunity for the commercialized point of care testing for dengue diagnosis in the future. |
| first_indexed | 2025-11-15T11:59:27Z |
| format | Article |
| id | upm-74813 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:59:27Z |
| publishDate | 2018 |
| publisher | Oriental Scientific Publishing Company |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-748132020-04-20T17:41:38Z http://psasir.upm.edu.my/id/eprint/74813/ Laboratory diagnosis and potential application of nucleic acid biosensor approach for early detection of dengue virus infections Abdul Rashid, Jahwarhar Izuan Yusof, Nor Azah Dengue fever is caused by the dengue virus, the genus of Flaviviridae virus family. Until now, there is no specific medication to kill the dengue virus and patients just solely depend on the treatment of the dengue infection symptoms. Thus, a highly sensitive and rapid diagnostic tool for early diagnosis of dengue virus is very desirable, especially in resource limited-condition. We briefly review pro and cons of existing diagnostic methods for the detection of dengue virus (virus isolation, PCR, NS1Ag, Serology). We also highlight the recent advances of the biosensor technology in the dengue diagnostic dengue as a promising point-of-care diagnostic in the future. The DNA based biosensor technology combined miniaturized sample preparation offers a good opportunity for the commercialized point of care testing for dengue diagnosis in the future. Oriental Scientific Publishing Company 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/74813/1/Laboratory%20diagnosis%20and%20potential%20application%20of%20nucleic%20acid%20biosensor%20approach%20for%20early%20detection%20of%20dengue%20virus%20infections.pdf Abdul Rashid, Jahwarhar Izuan and Yusof, Nor Azah (2018) Laboratory diagnosis and potential application of nucleic acid biosensor approach for early detection of dengue virus infections. Biosciences, Biotechnology Research Asia, 15 (2). 245 - 255. ISSN 0973-1245; ESSN: 2456-2602 10.13005/bbra/2628 |
| spellingShingle | Abdul Rashid, Jahwarhar Izuan Yusof, Nor Azah Laboratory diagnosis and potential application of nucleic acid biosensor approach for early detection of dengue virus infections |
| title | Laboratory diagnosis and potential application of nucleic acid biosensor approach for early detection of dengue virus infections |
| title_full | Laboratory diagnosis and potential application of nucleic acid biosensor approach for early detection of dengue virus infections |
| title_fullStr | Laboratory diagnosis and potential application of nucleic acid biosensor approach for early detection of dengue virus infections |
| title_full_unstemmed | Laboratory diagnosis and potential application of nucleic acid biosensor approach for early detection of dengue virus infections |
| title_short | Laboratory diagnosis and potential application of nucleic acid biosensor approach for early detection of dengue virus infections |
| title_sort | laboratory diagnosis and potential application of nucleic acid biosensor approach for early detection of dengue virus infections |
| url | http://psasir.upm.edu.my/id/eprint/74813/ http://psasir.upm.edu.my/id/eprint/74813/ http://psasir.upm.edu.my/id/eprint/74813/1/Laboratory%20diagnosis%20and%20potential%20application%20of%20nucleic%20acid%20biosensor%20approach%20for%20early%20detection%20of%20dengue%20virus%20infections.pdf |