Water extract of Clinacanthus nutans leaves exhibits in vitro, ex vivo and in vivo anti-angiogenic activities in endothelial cell via suppression of cell proliferation

QR Code

Water extract of Clinacanthus nutans leaves exhibits in vitro, ex vivo and in vivo anti-angiogenic activities in endothelial cell via suppression of cell proliferation

Background: Clinacanthus nutans (Burm. f.) Lindau. has traditionally been using in South East Asia countries to manage cancer. However, scientific evidence is generally lacking to support this traditional claim. This study aims to investigate the in vitro, ex-vivo and in vivo effects of C. nutans ex...

Full description

Bibliographic Details
Main Authors:	Ng, Chin Theng, Fong, Lai Yen, Tan, Jun Jie, Rajab, Nor Fadilah, Abas, Faridah, Shaari, Khozirah, Chan, Kok Meng, Fariza Juliana, Yong, Yoke Keong
Format:	Article
Language:	English
Published:	BMC 2018
Online Access:	http://psasir.upm.edu.my/id/eprint/74422/ http://psasir.upm.edu.my/id/eprint/74422/1/Water%20extract%20of%20Clinacanthus%20nutans%20leaves%20exhibits%20in%20vitro%2C%20ex%20vivo%20and%20in%20vivo%20anti-angiogenic%20activities%20in%20endothelial%20cell%20via%20suppression%20of%20cell%20proliferation.pdf

Similar Items

Malaysian Tualang honey suppresses the angiogenic events in endothelial cells induced by vascular endothelial growth factor
by: Ahmad Firdaus Abdul Khalid,, et al.
Published: (2022)

Malaysian Tualang Honey suppresses the angiogenic events in Endothelial cells induced by vascular endothelial growth factor
by: Abdul Khalid, Ahmad Firdaus, et al.
Published: (2022)

Immunomodulatory and cell cycle regulatory effects of clinacanthus nutans
by: Ghazali, Wan Afiqah Syahirah Wan @ Wan Azmi
Published: (2018)

Immunomodulatory potential of Clinacanthus nutans extracts in the co-culture of triple-negative breast cancer cells, MDA-MB-231, and THP-1 macrophages
by: Nordin, Fariza Juliana, et al.
Published: (2021)

Chemopreventive potential of water and methanolic extracts of Clinacanthus nutans (Burm.f.) Lindau on colon cancer in vitro and in vivo
by: Kura, Mariamu Nyako
Published: (2015)

Assessment of cytotoxicity potency of paclitaxel in combination with Clinacanthus Nutans extracts on human MDA-MB-231 breast cancer cells
by: Nur Hasnieza Mohd Rosli,, et al.
Published: (2018)

Astaxanthin's anti-angiogenic Effects: Network pharmacology and functional validation in endothelial cells
by: Barizi, Anis Zuhaida Mamnun, et al.
Published: (2025)

Clinacanthus nutans aqueous extract suppresses the release of histamine and β-Hexosaminidase inin-vitro model of IgE-mediated mast cell degranulation
by: Kow, Audrey Siew Foong, et al.
Published: (2020)

β-mangostin suppresses LA-7 cells proliferation in vitro and in vivo: involvement of antioxidant enzyme modulation; suppression of matrix metalloproteinase and α6β4 integrin signalling pathways
by: Mohan, Suvitha Syam, et al.
Published: (2016)

Ex vivo modelling of oesophago-gastric cancer
by: Saunders, John
Published: (2017)

Response to loading in ex vivo bovine bone
by: Khalid, Kamarul Ariffin, et al.
Published: (2011)

Alanyl-glutamine improves pancreatic ß-cell function following ex vivo inflammatory challenge
by: Cruzat, Vinicius, et al.
Published: (2015)

Anti hypercholesterolemia and antioxidant effects of Belalai Gajah (Clinacanthus nutans L.) extracts and proto-catechuic acid rich fraction, in vivo and in vitro
by: Nadarajan, Sarega
Published: (2016)

In vitro and in vivo effect of Clinacanthus nutans (Burm. f.) Lindau aqueous extract on IgE and IgG-mediated allergy pathways
by: Kow, Audrey Siew Foong
Published: (2021)

Cytotoxicity Of Clinacanthus Nutans Methanol-Water Extract On Huh-7 Cell Line
by: Chuah, Jia Jun
Published: (2017)

Protein expression patterns in HEK-blue-cells treated with Clinacanthus nutans extracts
by: Yang, Shun Kai, et al.
Published: (2020)

Transcriptome Analysis Of Cervical Cancer Cells (Hela) Treated With Clinacanthus Nutans Extract
by: Haron, Nor Hasyimah
Published: (2021)

Anti-angiogenic effect of Ardisia crispa root in human umbilical vein endothelial cells (HUVECS)
by: Lim, Wen Jun, et al.
Published: (2015)

Conditioned Medium From Bone Marrow-Derived Mesenchymal Stem Cells For Ex Vivo Expansion Of Cardiac Stem Cells
by: Umar Fuaad, Mimi Zulaikha
Published: (2016)

Antioxidants, endothelial dysfunction, and DCS: In vitro and in vivo study
by: Wang, Q., et al.
Published: (2015)

Anti-angiogenic effect of Ardisia crispa root invitro and in vivo and its potential pathway(s)
by: Abd Hamid @ Abdul Razak, Roslida, et al.
Published: (2016)

Typhonium flagelliforme inhibits the proliferation of murine leukemia WEHI-3 cells in vitro and induces apoptosis in vivo
by: Mohan, Syam, et al.
Published: (2010)

Preparation of Biomaterials Using Fish Collagen and Seaweed Alginate to Promote in-vivo Cell Growth and Proliferation Activity
by: Woo, Mun Jeng
Published: (2019)

NMR and LCMS analytical platforms exhibited the nephroprotective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity in the in vitro condition
by: Mahmod, Ilya Iryani, et al.
Published: (2020)

Cytotoxicity of Clinacanthus Nutans Extracts on Human Hepatoma (HepG2) Cell Line
by: Hazrulrizawati, Hamid, et al.
Published: (2016)

Clinacanthus nutans extracts are antioxidant with antiproliferative effect on cultured human cancer cell lines
by: Yong, Yoke Keong, et al.
Published: (2013)

Clinacanthus nutans Extracts Are Antioxidant with Antiproliferative Effect on Cultured Human Cancer Cell Lines
by: Yoke, Keong Yong, et al.
Published: (2013)

Infrared drying of Clinacanthus nutans leaves
by: Abdullah, Sriyana, et al.
Published: (2022)

Chlorogenic acid improves ex vivo vessel function and protects endothelial cells against HOCl-induced oxidative damage, via increased production of nitric oxide and induction of Hmox-1
by: Jiang, R., et al.
Published: (2016)

Chemical constituents from the butanol fraction of Clinacanthus nutans leaves
by: Zolkeflee, Nur Khaleeda Zulaikha, et al.
Published: (2022)

Ex-vivo expression of chemokine receptors on cells surrounding cutaneous nerves in patients with HIV-Associated sensory neuropathy
by: Mountford, Jenjira, et al.
Published: (2018)

Effect of vascular endothelial growth factor on stem cell and angiogenic gene markers of stem cell from human extracted deciduous teeth
by: Md Hashim, Siti Nurnasihah, et al.
Published: (2016)

Physicochemical characterisation of sunflower seed oil bodies ex-vivo
by: Fisk, Ian
Published: (2007)

Building an ex vivo model of breast cancer lung metastasis
by: Grey, James F.E.
Published: (2019)

Effects of light illumination and subculture frequency on biomass production in cell suspension cultures of Clinacanthus nutans
by: Bong, Fui Joo, et al.
Published: (2021)

Antiproliferative And Apoptosis Effects Of Clinacanthus Nutans Leaf Extract On Breast Cancer Cell (Mcf7)
by: Ismail, Noor Zafirah
Published: (2023)

Silver nanoparticles Clinacanthus nutans leaves extract induced apoptosis towards oral squamous cell carcinoma cell lines
by: Yakop, Fahmi, et al.
Published: (2019)

Eurycoma longifolia extract exhibits anti-atherosclerotic effects in an in-vivo model
by: A. J., Fakhria, et al.
Published: (2015)

Viability and topographical analysis of microencapsulated ß-cells exposed to a biotransformed tertiary bile acid: An ex vivo study
by: Mooranian, Armin, et al.
Published: (2016)

Ex-vivo generation of full term human amniotic fluid mesenchymal stem cells in xeno- and serum-free condition
by: Karrupiah, Thilakavathy, et al.
Published: (2015)