The 'checkmate' for iron between human host and invading bacteria: chess game analogy
Iron is an essential nutrient for all living organisms with critical roles in many biological processes. The mammalian host maintains the iron requirements by dietary intake, while the invading pathogenic bacteria compete with the host to obtain those absorbed irons. In order to limit the iron uptak...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Springer Verlag
2018
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| Online Access: | http://psasir.upm.edu.my/id/eprint/74104/ http://psasir.upm.edu.my/id/eprint/74104/1/The%20%27checkmate%27%20for%20iron%20between%20human%20host%20and%20invading%20bacteria%20chess%20game%20analogy.pdf |
| _version_ | 1848857433988923392 |
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| author | Kalidasan, V. Joseph, Narcisse Subbiah, Suresh Kumar Awang Hamat, Rukman Neela, Vasantha Kumari |
| author_facet | Kalidasan, V. Joseph, Narcisse Subbiah, Suresh Kumar Awang Hamat, Rukman Neela, Vasantha Kumari |
| author_sort | Kalidasan, V. |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Iron is an essential nutrient for all living organisms with critical roles in many biological processes. The mammalian host maintains the iron requirements by dietary intake, while the invading pathogenic bacteria compete with the host to obtain those absorbed irons. In order to limit the iron uptake by the bacteria, the human host employs numerous iron binding proteins and withholding defense mechanisms that capture iron from the microbial invaders. To counteract, the bacteria cope with the iron limitation imposed by the host by expressing various iron acquisition systems, allowing them to achieve effective iron homeostasis. The armamentarium used by the human host and invading bacteria, leads to the dilemma of who wins the ultimate war for iron. |
| first_indexed | 2025-11-15T11:57:29Z |
| format | Article |
| id | upm-74104 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:57:29Z |
| publishDate | 2018 |
| publisher | Springer Verlag |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-741042020-04-26T17:11:38Z http://psasir.upm.edu.my/id/eprint/74104/ The 'checkmate' for iron between human host and invading bacteria: chess game analogy Kalidasan, V. Joseph, Narcisse Subbiah, Suresh Kumar Awang Hamat, Rukman Neela, Vasantha Kumari Iron is an essential nutrient for all living organisms with critical roles in many biological processes. The mammalian host maintains the iron requirements by dietary intake, while the invading pathogenic bacteria compete with the host to obtain those absorbed irons. In order to limit the iron uptake by the bacteria, the human host employs numerous iron binding proteins and withholding defense mechanisms that capture iron from the microbial invaders. To counteract, the bacteria cope with the iron limitation imposed by the host by expressing various iron acquisition systems, allowing them to achieve effective iron homeostasis. The armamentarium used by the human host and invading bacteria, leads to the dilemma of who wins the ultimate war for iron. Springer Verlag 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/74104/1/The%20%27checkmate%27%20for%20iron%20between%20human%20host%20and%20invading%20bacteria%20chess%20game%20analogy.pdf Kalidasan, V. and Joseph, Narcisse and Subbiah, Suresh Kumar and Awang Hamat, Rukman and Neela, Vasantha Kumari (2018) The 'checkmate' for iron between human host and invading bacteria: chess game analogy. Indian Journal of Microbiology, 58 (3). 257 - 267. ISSN 0046-8991; ESSN: 0973-7715 10.1007/s12088-018-0740-2 |
| spellingShingle | Kalidasan, V. Joseph, Narcisse Subbiah, Suresh Kumar Awang Hamat, Rukman Neela, Vasantha Kumari The 'checkmate' for iron between human host and invading bacteria: chess game analogy |
| title | The 'checkmate' for iron between human host and invading bacteria: chess game analogy |
| title_full | The 'checkmate' for iron between human host and invading bacteria: chess game analogy |
| title_fullStr | The 'checkmate' for iron between human host and invading bacteria: chess game analogy |
| title_full_unstemmed | The 'checkmate' for iron between human host and invading bacteria: chess game analogy |
| title_short | The 'checkmate' for iron between human host and invading bacteria: chess game analogy |
| title_sort | 'checkmate' for iron between human host and invading bacteria: chess game analogy |
| url | http://psasir.upm.edu.my/id/eprint/74104/ http://psasir.upm.edu.my/id/eprint/74104/ http://psasir.upm.edu.my/id/eprint/74104/1/The%20%27checkmate%27%20for%20iron%20between%20human%20host%20and%20invading%20bacteria%20chess%20game%20analogy.pdf |