Synthesis and characterization of new cholinium-based ionic liquids for antimicrobial application

A series of new cholinium-based ionic liquids (ILs) was synthesized by using simple neutralization reaction. The synthesized ILs were choline 3,5-dinitrosalicylate, choline gallate, choline s-(+)-2-(4-isobutylphenyl)propionate, choline behenate and choline peracetate. All the synthesized cholinium-b...

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Main Authors: Jumbri, Khairulazhar, Mah Noh, Nor Suzy Farahana, Ahmad, Nur Afiqah, Abdul Rahman, Mohd Basyaruddin, Ahmad, Haslina
Format: Article
Published: Akademia Baru 2018
Online Access:http://psasir.upm.edu.my/id/eprint/74051/
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author Jumbri, Khairulazhar
Mah Noh, Nor Suzy Farahana
Ahmad, Nur Afiqah
Abdul Rahman, Mohd Basyaruddin
Ahmad, Haslina
author_facet Jumbri, Khairulazhar
Mah Noh, Nor Suzy Farahana
Ahmad, Nur Afiqah
Abdul Rahman, Mohd Basyaruddin
Ahmad, Haslina
author_sort Jumbri, Khairulazhar
building UPM Institutional Repository
collection Online Access
description A series of new cholinium-based ionic liquids (ILs) was synthesized by using simple neutralization reaction. The synthesized ILs were choline 3,5-dinitrosalicylate, choline gallate, choline s-(+)-2-(4-isobutylphenyl)propionate, choline behenate and choline peracetate. All the synthesized cholinium-based ILs were characterized by using FT-IR, 1 H and 13C NMR, mass spectrometry, thermogravimetric and differential scanning calorimetry. Result obtained from all characterization techniques confirmed the formation of these cholinium-based ILs. These ILs were then tested for their antimicrobial properties. Anti-microbial test was carried out towards seven types of bacteria which consist of three Gram-positive bacteria, Bacillus subtilis (B29), Staphylococcus aureus (S276), Staphylococcus epidermidis (S273), two Gram-negative bacteria, Pseudomonas aeruginosa (ATCC 15442) and Escherichia coli (E266) and two types of yeasts, Candida albicans (9002) and Candida tropicalis (A3). Streptomycin and Nystatin were used for all bacteria as standard. There is one cholinium-based IL shows excellent inhibition of microbes from growth. Choline peracetate was found to inhibit Candida albicans (9002) as good as the standard, Streptomycin which perform highest of inhibition zone diameter, 25 mm.
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institution Universiti Putra Malaysia
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last_indexed 2025-11-15T11:57:19Z
publishDate 2018
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spelling upm-740512023-05-29T02:09:28Z http://psasir.upm.edu.my/id/eprint/74051/ Synthesis and characterization of new cholinium-based ionic liquids for antimicrobial application Jumbri, Khairulazhar Mah Noh, Nor Suzy Farahana Ahmad, Nur Afiqah Abdul Rahman, Mohd Basyaruddin Ahmad, Haslina A series of new cholinium-based ionic liquids (ILs) was synthesized by using simple neutralization reaction. The synthesized ILs were choline 3,5-dinitrosalicylate, choline gallate, choline s-(+)-2-(4-isobutylphenyl)propionate, choline behenate and choline peracetate. All the synthesized cholinium-based ILs were characterized by using FT-IR, 1 H and 13C NMR, mass spectrometry, thermogravimetric and differential scanning calorimetry. Result obtained from all characterization techniques confirmed the formation of these cholinium-based ILs. These ILs were then tested for their antimicrobial properties. Anti-microbial test was carried out towards seven types of bacteria which consist of three Gram-positive bacteria, Bacillus subtilis (B29), Staphylococcus aureus (S276), Staphylococcus epidermidis (S273), two Gram-negative bacteria, Pseudomonas aeruginosa (ATCC 15442) and Escherichia coli (E266) and two types of yeasts, Candida albicans (9002) and Candida tropicalis (A3). Streptomycin and Nystatin were used for all bacteria as standard. There is one cholinium-based IL shows excellent inhibition of microbes from growth. Choline peracetate was found to inhibit Candida albicans (9002) as good as the standard, Streptomycin which perform highest of inhibition zone diameter, 25 mm. Akademia Baru 2018-12-01 Article PeerReviewed Jumbri, Khairulazhar and Mah Noh, Nor Suzy Farahana and Ahmad, Nur Afiqah and Abdul Rahman, Mohd Basyaruddin and Ahmad, Haslina (2018) Synthesis and characterization of new cholinium-based ionic liquids for antimicrobial application. Journal of Advanced Research in Fluid Mechanics and Thermal Sciences, 42 (1). 16 - 23. ISSN 2289 - 7879 https://akademiabaru.com/submit/index.php/arfmts/article/view/2134
spellingShingle Jumbri, Khairulazhar
Mah Noh, Nor Suzy Farahana
Ahmad, Nur Afiqah
Abdul Rahman, Mohd Basyaruddin
Ahmad, Haslina
Synthesis and characterization of new cholinium-based ionic liquids for antimicrobial application
title Synthesis and characterization of new cholinium-based ionic liquids for antimicrobial application
title_full Synthesis and characterization of new cholinium-based ionic liquids for antimicrobial application
title_fullStr Synthesis and characterization of new cholinium-based ionic liquids for antimicrobial application
title_full_unstemmed Synthesis and characterization of new cholinium-based ionic liquids for antimicrobial application
title_short Synthesis and characterization of new cholinium-based ionic liquids for antimicrobial application
title_sort synthesis and characterization of new cholinium-based ionic liquids for antimicrobial application
url http://psasir.upm.edu.my/id/eprint/74051/
http://psasir.upm.edu.my/id/eprint/74051/