Seroprevalence of leptospiral antibodies among market workers and food handlers in the central state of Malaysia
Objective:The high prevalence of leptospirosis in humans is of great public health concern, particularly in tropical and subtropical regions. This study aimed to determine the seroprevalence of leptospiral antibodies and distribution of serovars, and to assess the usefulness of enzyme-linked immunos...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018
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| Online Access: | http://psasir.upm.edu.my/id/eprint/73872/ http://psasir.upm.edu.my/id/eprint/73872/1/Seroprevalence%20of%20leptospiral%20antibodies%20among%20market%20workers%20and%20food%20handlers%20in%20the%20central%20state%20of%20Malaysia.pdf |
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| author | S., Samsudin S. N. S., Sakinah Osman, Malina B. A., Norliza M. A., Noh A., Fairuz Tengku Jamaluddin, Tengku Zetty Maztura Awang Hamat, Rukman W. M., Zahiruddin S., Mohd Nazri S., Sukeri B. D., Aziah I., Zawaha A. W., Zainudin N. A., Munirah Mohd Desa, Mohd Nasir Neela, Vasantha Kumari Masri, Siti Norbaya |
| author_facet | S., Samsudin S. N. S., Sakinah Osman, Malina B. A., Norliza M. A., Noh A., Fairuz Tengku Jamaluddin, Tengku Zetty Maztura Awang Hamat, Rukman W. M., Zahiruddin S., Mohd Nazri S., Sukeri B. D., Aziah I., Zawaha A. W., Zainudin N. A., Munirah Mohd Desa, Mohd Nasir Neela, Vasantha Kumari Masri, Siti Norbaya |
| author_sort | S., Samsudin |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Objective:The high prevalence of leptospirosis in humans is of great public health concern, particularly in tropical and subtropical regions. This study aimed to determine the seroprevalence of leptospiral antibodies and distribution of serovars, and to assess the usefulness of enzyme-linked immunosorbent assay (ELISA) as a screening method for leptospiral antibodies in a high-risk healthy community. Methods: Cross-sectional study of 231 market workers and food handlers in wet markets and food premises from two localities in central Malaysia. Respondents' background information was obtained using a questionnaire. Serum samples were tested for leptospiral antibodies using ELISA and microscopic agglutination test (MAT). Results: Seroprevalence of leptospirosis among healthy workers was 46.3%. Detection of seropositivity was higher by MAT (46%) than ELISA (15%). We observed high seropositivity among local workers (49%), food handlers (49.5%), females (60.8%) and those aged 34 years and older (46.3%). Local strain LEP175 was the predominant serovar, followed by WHO strain Patoc. Conclusion: Overall seroprevalence among healthy food handlers and market workers was high in this study. The workplace places susceptible individuals at risk of leptospirosis. |
| first_indexed | 2025-11-15T11:56:42Z |
| format | Article |
| id | upm-73872 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:56:42Z |
| publishDate | 2018 |
| publisher | Wiley |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-738722020-04-29T20:11:22Z http://psasir.upm.edu.my/id/eprint/73872/ Seroprevalence of leptospiral antibodies among market workers and food handlers in the central state of Malaysia S., Samsudin S. N. S., Sakinah Osman, Malina B. A., Norliza M. A., Noh A., Fairuz Tengku Jamaluddin, Tengku Zetty Maztura Awang Hamat, Rukman W. M., Zahiruddin S., Mohd Nazri S., Sukeri B. D., Aziah I., Zawaha A. W., Zainudin N. A., Munirah Mohd Desa, Mohd Nasir Neela, Vasantha Kumari Masri, Siti Norbaya Objective:The high prevalence of leptospirosis in humans is of great public health concern, particularly in tropical and subtropical regions. This study aimed to determine the seroprevalence of leptospiral antibodies and distribution of serovars, and to assess the usefulness of enzyme-linked immunosorbent assay (ELISA) as a screening method for leptospiral antibodies in a high-risk healthy community. Methods: Cross-sectional study of 231 market workers and food handlers in wet markets and food premises from two localities in central Malaysia. Respondents' background information was obtained using a questionnaire. Serum samples were tested for leptospiral antibodies using ELISA and microscopic agglutination test (MAT). Results: Seroprevalence of leptospirosis among healthy workers was 46.3%. Detection of seropositivity was higher by MAT (46%) than ELISA (15%). We observed high seropositivity among local workers (49%), food handlers (49.5%), females (60.8%) and those aged 34 years and older (46.3%). Local strain LEP175 was the predominant serovar, followed by WHO strain Patoc. Conclusion: Overall seroprevalence among healthy food handlers and market workers was high in this study. The workplace places susceptible individuals at risk of leptospirosis. Wiley 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/73872/1/Seroprevalence%20of%20leptospiral%20antibodies%20among%20market%20workers%20and%20food%20handlers%20in%20the%20central%20state%20of%20Malaysia.pdf S., Samsudin and S. N. S., Sakinah and Osman, Malina and B. A., Norliza and M. A., Noh and A., Fairuz and Tengku Jamaluddin, Tengku Zetty Maztura and Awang Hamat, Rukman and W. M., Zahiruddin and S., Mohd Nazri and S., Sukeri and B. D., Aziah and I., Zawaha and A. W., Zainudin and N. A., Munirah and Mohd Desa, Mohd Nasir and Neela, Vasantha Kumari and Masri, Siti Norbaya (2018) Seroprevalence of leptospiral antibodies among market workers and food handlers in the central state of Malaysia. Tropical Medicine and International Health, 23 (3). 327 - 333. ISSN 1360-2276; ESSN: 1365-3156 https://onlinelibrary.wiley.com/doi/full/10.1111/tmi.13033 10.1111/tmi.13033 |
| spellingShingle | S., Samsudin S. N. S., Sakinah Osman, Malina B. A., Norliza M. A., Noh A., Fairuz Tengku Jamaluddin, Tengku Zetty Maztura Awang Hamat, Rukman W. M., Zahiruddin S., Mohd Nazri S., Sukeri B. D., Aziah I., Zawaha A. W., Zainudin N. A., Munirah Mohd Desa, Mohd Nasir Neela, Vasantha Kumari Masri, Siti Norbaya Seroprevalence of leptospiral antibodies among market workers and food handlers in the central state of Malaysia |
| title | Seroprevalence of leptospiral antibodies among market workers and food handlers in the central state of Malaysia |
| title_full | Seroprevalence of leptospiral antibodies among market workers and food handlers in the central state of Malaysia |
| title_fullStr | Seroprevalence of leptospiral antibodies among market workers and food handlers in the central state of Malaysia |
| title_full_unstemmed | Seroprevalence of leptospiral antibodies among market workers and food handlers in the central state of Malaysia |
| title_short | Seroprevalence of leptospiral antibodies among market workers and food handlers in the central state of Malaysia |
| title_sort | seroprevalence of leptospiral antibodies among market workers and food handlers in the central state of malaysia |
| url | http://psasir.upm.edu.my/id/eprint/73872/ http://psasir.upm.edu.my/id/eprint/73872/ http://psasir.upm.edu.my/id/eprint/73872/ http://psasir.upm.edu.my/id/eprint/73872/1/Seroprevalence%20of%20leptospiral%20antibodies%20among%20market%20workers%20and%20food%20handlers%20in%20the%20central%20state%20of%20Malaysia.pdf |