Role of herbal medicines in vitiligo treatment - current status and future perspectives

Vitiligo is a depigmentation disorder with complex causes. Nonetheless, recent progress has been made to unravel the pathophysiology of vitiligo. In this review, we provide an overview of the currently known herbal medicine for vitiligo treatment and also highlighted the herbs that have been used in...

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Main Authors: Narayanaswamy, Radhakrishnan, Ismail, Intan Safinar
Format: Article
Language:English
Published: Innovare Academic Sciences 2018
Online Access:http://psasir.upm.edu.my/id/eprint/73818/
http://psasir.upm.edu.my/id/eprint/73818/1/Role%20of%20herbal%20medicines%20in%20vitiligo%20treatment%20-%20current%20status%20and%20future%20perspectives.pdf
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author Narayanaswamy, Radhakrishnan
Ismail, Intan Safinar
author_facet Narayanaswamy, Radhakrishnan
Ismail, Intan Safinar
author_sort Narayanaswamy, Radhakrishnan
building UPM Institutional Repository
collection Online Access
description Vitiligo is a depigmentation disorder with complex causes. Nonetheless, recent progress has been made to unravel the pathophysiology of vitiligo. In this review, we provide an overview of the currently known herbal medicine for vitiligo treatment and also highlighted the herbs that have been used in clinical trials. In view of traditional uses, herbs such as Ammi visnaga L., Angelica sinensis, Eclipta alba L, Ginkgo biloba, Picrorhiza kurroa Royle Ex Benth, and Psoralea corylifolia L, have been highlighted. Enormous efforts in vitiligo drug discovery are currently needed. Interleukin-17 inhibition, tumor necrosis factor-alpha inhibition, heat shock protein-70i (HSP70i) inhibition, keratinocyte turnover modulators, and regulatory T cells (Tregs) modulators have been discussed as promising new targets for vitiligo drug development. Thus, we strongly believe that this review may be useful for rationalize new herbal drug for vitiligo treatment.
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spelling upm-738182020-05-06T18:36:20Z http://psasir.upm.edu.my/id/eprint/73818/ Role of herbal medicines in vitiligo treatment - current status and future perspectives Narayanaswamy, Radhakrishnan Ismail, Intan Safinar Vitiligo is a depigmentation disorder with complex causes. Nonetheless, recent progress has been made to unravel the pathophysiology of vitiligo. In this review, we provide an overview of the currently known herbal medicine for vitiligo treatment and also highlighted the herbs that have been used in clinical trials. In view of traditional uses, herbs such as Ammi visnaga L., Angelica sinensis, Eclipta alba L, Ginkgo biloba, Picrorhiza kurroa Royle Ex Benth, and Psoralea corylifolia L, have been highlighted. Enormous efforts in vitiligo drug discovery are currently needed. Interleukin-17 inhibition, tumor necrosis factor-alpha inhibition, heat shock protein-70i (HSP70i) inhibition, keratinocyte turnover modulators, and regulatory T cells (Tregs) modulators have been discussed as promising new targets for vitiligo drug development. Thus, we strongly believe that this review may be useful for rationalize new herbal drug for vitiligo treatment. Innovare Academic Sciences 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/73818/1/Role%20of%20herbal%20medicines%20in%20vitiligo%20treatment%20-%20current%20status%20and%20future%20perspectives.pdf Narayanaswamy, Radhakrishnan and Ismail, Intan Safinar (2018) Role of herbal medicines in vitiligo treatment - current status and future perspectives. Asian Journal of Pharmaceutical and Clinical Research, 11 (9). 19 - 23. ISSN 0974-2441; ESSN 2455-3891 https://innovareacademics.in/journals/index.php/ajpcr/article/view/26830 10.22159/ajpcr.2018.v11i9.26830
spellingShingle Narayanaswamy, Radhakrishnan
Ismail, Intan Safinar
Role of herbal medicines in vitiligo treatment - current status and future perspectives
title Role of herbal medicines in vitiligo treatment - current status and future perspectives
title_full Role of herbal medicines in vitiligo treatment - current status and future perspectives
title_fullStr Role of herbal medicines in vitiligo treatment - current status and future perspectives
title_full_unstemmed Role of herbal medicines in vitiligo treatment - current status and future perspectives
title_short Role of herbal medicines in vitiligo treatment - current status and future perspectives
title_sort role of herbal medicines in vitiligo treatment - current status and future perspectives
url http://psasir.upm.edu.my/id/eprint/73818/
http://psasir.upm.edu.my/id/eprint/73818/
http://psasir.upm.edu.my/id/eprint/73818/
http://psasir.upm.edu.my/id/eprint/73818/1/Role%20of%20herbal%20medicines%20in%20vitiligo%20treatment%20-%20current%20status%20and%20future%20perspectives.pdf