Response surface optimization of high antioxidative extraction from Curcuma zedoaria leaves
Response surface methodology (RSM) has been fully utilized in this study to model and optimize the extraction conditions for maximum antioxidant compounds activity from Curcuma zedoaria leaves. This work was carried out based on three factor/5 level of central composite rotatable design (CCRD) and t...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Penerbit Akademia Baru
2018
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/73778/ http://psasir.upm.edu.my/id/eprint/73778/1/Response%20surface%20optimization%20of%20high%20antioxidative%20extraction%20from%20Curcuma%20zedoaria%20leaves.pdf |
| _version_ | 1848857357867548672 |
|---|---|
| author | Abd Gani, Siti Salwa Azahar, Nur Fauwizah Mokhtar, Nor Fadzillah |
| author_facet | Abd Gani, Siti Salwa Azahar, Nur Fauwizah Mokhtar, Nor Fadzillah |
| author_sort | Abd Gani, Siti Salwa |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Response surface methodology (RSM) has been fully utilized in this study to model and optimize the extraction conditions for maximum antioxidant compounds activity from Curcuma zedoaria leaves. This work was carried out based on three factor/5 level of central composite rotatable design (CCRD) and three independent variables, namely extraction temperature (60-80 ο C), processing time (80-120min) and solvent concentration (70-90 v/v %). The experimental data was subjected to total antioxidant activity measured by the 1, 1-diphenyl-2-picrylhdrazyl (DPPH)-radical scavenging, β-carotene bleaching (BCB) inhibition as well as ferric ion reducing antioxidant power (FRAP). By using the desirability functions, the optimal conditions were found to be at temperature 75 ο C, 92 min and (90:10 v/v%) ethanol concentration for the highest total antioxidants values for DPPH, BCB and FRAP were 85.76%, 81.35 % and 5.08 mM Fe 2+ g/DW respectively, which closely agreed with the predicted values of 87.59%, 82.29%, 5.25 mM Fe 2+ g/DW respectively. Thus, indicating the suitability of the model employed in RSM to optimizing the extraction conditions. |
| first_indexed | 2025-11-15T11:56:16Z |
| format | Article |
| id | upm-73778 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:56:16Z |
| publishDate | 2018 |
| publisher | Penerbit Akademia Baru |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-737782020-05-08T16:10:48Z http://psasir.upm.edu.my/id/eprint/73778/ Response surface optimization of high antioxidative extraction from Curcuma zedoaria leaves Abd Gani, Siti Salwa Azahar, Nur Fauwizah Mokhtar, Nor Fadzillah Response surface methodology (RSM) has been fully utilized in this study to model and optimize the extraction conditions for maximum antioxidant compounds activity from Curcuma zedoaria leaves. This work was carried out based on three factor/5 level of central composite rotatable design (CCRD) and three independent variables, namely extraction temperature (60-80 ο C), processing time (80-120min) and solvent concentration (70-90 v/v %). The experimental data was subjected to total antioxidant activity measured by the 1, 1-diphenyl-2-picrylhdrazyl (DPPH)-radical scavenging, β-carotene bleaching (BCB) inhibition as well as ferric ion reducing antioxidant power (FRAP). By using the desirability functions, the optimal conditions were found to be at temperature 75 ο C, 92 min and (90:10 v/v%) ethanol concentration for the highest total antioxidants values for DPPH, BCB and FRAP were 85.76%, 81.35 % and 5.08 mM Fe 2+ g/DW respectively, which closely agreed with the predicted values of 87.59%, 82.29%, 5.25 mM Fe 2+ g/DW respectively. Thus, indicating the suitability of the model employed in RSM to optimizing the extraction conditions. Penerbit Akademia Baru 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/73778/1/Response%20surface%20optimization%20of%20high%20antioxidative%20extraction%20from%20Curcuma%20zedoaria%20leaves.pdf Abd Gani, Siti Salwa and Azahar, Nur Fauwizah and Mokhtar, Nor Fadzillah (2018) Response surface optimization of high antioxidative extraction from Curcuma zedoaria leaves. Journal of Advanced Research in Fluid Mechanics and Thermal Sciences, 43 (1). 90 - 103. ISSN 2289-7879 http://www.akademiabaru.com/arfmts.html |
| spellingShingle | Abd Gani, Siti Salwa Azahar, Nur Fauwizah Mokhtar, Nor Fadzillah Response surface optimization of high antioxidative extraction from Curcuma zedoaria leaves |
| title | Response surface optimization of high antioxidative extraction from Curcuma zedoaria leaves |
| title_full | Response surface optimization of high antioxidative extraction from Curcuma zedoaria leaves |
| title_fullStr | Response surface optimization of high antioxidative extraction from Curcuma zedoaria leaves |
| title_full_unstemmed | Response surface optimization of high antioxidative extraction from Curcuma zedoaria leaves |
| title_short | Response surface optimization of high antioxidative extraction from Curcuma zedoaria leaves |
| title_sort | response surface optimization of high antioxidative extraction from curcuma zedoaria leaves |
| url | http://psasir.upm.edu.my/id/eprint/73778/ http://psasir.upm.edu.my/id/eprint/73778/ http://psasir.upm.edu.my/id/eprint/73778/1/Response%20surface%20optimization%20of%20high%20antioxidative%20extraction%20from%20Curcuma%20zedoaria%20leaves.pdf |