Recent development of SPR spectroscopy as potential method for diagnosis of dengue virus E-protein
Purpose: This paper aims to review the potential application of surface plasmon resonance (SPR) in diagnosis of dengue virus (DENV-2) E-protein and the development of SPR to become an alternative DENV sensor. Design/methodology/approach: In this review, the existing standard laboratory techniques to...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Emerald
2018
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| Online Access: | http://psasir.upm.edu.my/id/eprint/73717/ http://psasir.upm.edu.my/id/eprint/73717/1/PROTEIN.pdf |
| _version_ | 1848857344663879680 |
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| author | Sheh Omar, Nur Alia Yap, Wing Fen |
| author_facet | Sheh Omar, Nur Alia Yap, Wing Fen |
| author_sort | Sheh Omar, Nur Alia |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Purpose: This paper aims to review the potential application of surface plasmon resonance (SPR) in diagnosis of dengue virus (DENV-2) E-protein and the development of SPR to become an alternative DENV sensor. Design/methodology/approach: In this review, the existing standard laboratory techniques to diagnosis of DENV are discussed, together with their drawbacks. To overcome these drawbacks, SPR has been aimed to be a valuable optical biosensor for identification of antibodies to the DENV antigen. The review also includes the future studies on three-dimensional poly(amidoamine) (PAMAM) dendrimer-surface-assembled monolayer (SAM)-Au multilayer thin films, which are envisaged to have high potential sensitive and selective detection ability toward target E-proteins. Findings: Application of SPR in diagnosis of DENV emerged over recent years. A wide range of immobilized biorecognition molecules have been developed to combine with SPR as an effective sensor. The detection limit, sensitivity and selectivity of SPR sensing in DENV have been enhanced from time to time, until the present. Originality/value:
The main purpose of this review is to provide authors with up-to-date and useful information on sensing DENV using SPR and to introduce a novel three-dimensional PAMAM-SAM-Au multilayer thin films for future research on SPR sensing applications. |
| first_indexed | 2025-11-15T11:56:04Z |
| format | Article |
| id | upm-73717 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:56:04Z |
| publishDate | 2018 |
| publisher | Emerald |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-737172021-07-15T23:42:17Z http://psasir.upm.edu.my/id/eprint/73717/ Recent development of SPR spectroscopy as potential method for diagnosis of dengue virus E-protein Sheh Omar, Nur Alia Yap, Wing Fen Purpose: This paper aims to review the potential application of surface plasmon resonance (SPR) in diagnosis of dengue virus (DENV-2) E-protein and the development of SPR to become an alternative DENV sensor. Design/methodology/approach: In this review, the existing standard laboratory techniques to diagnosis of DENV are discussed, together with their drawbacks. To overcome these drawbacks, SPR has been aimed to be a valuable optical biosensor for identification of antibodies to the DENV antigen. The review also includes the future studies on three-dimensional poly(amidoamine) (PAMAM) dendrimer-surface-assembled monolayer (SAM)-Au multilayer thin films, which are envisaged to have high potential sensitive and selective detection ability toward target E-proteins. Findings: Application of SPR in diagnosis of DENV emerged over recent years. A wide range of immobilized biorecognition molecules have been developed to combine with SPR as an effective sensor. The detection limit, sensitivity and selectivity of SPR sensing in DENV have been enhanced from time to time, until the present. Originality/value: The main purpose of this review is to provide authors with up-to-date and useful information on sensing DENV using SPR and to introduce a novel three-dimensional PAMAM-SAM-Au multilayer thin films for future research on SPR sensing applications. Emerald 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/73717/1/PROTEIN.pdf Sheh Omar, Nur Alia and Yap, Wing Fen (2018) Recent development of SPR spectroscopy as potential method for diagnosis of dengue virus E-protein. Sensor Review, 38 (1). 106 - 116. ISSN 0260-2288 https://www.emerald.com/insight/content/doi/10.1108/SR-07-2017-0130/full/html 10.1108/SR-07-2017-0130 |
| spellingShingle | Sheh Omar, Nur Alia Yap, Wing Fen Recent development of SPR spectroscopy as potential method for diagnosis of dengue virus E-protein |
| title | Recent development of SPR spectroscopy as potential method for diagnosis of dengue virus E-protein |
| title_full | Recent development of SPR spectroscopy as potential method for diagnosis of dengue virus E-protein |
| title_fullStr | Recent development of SPR spectroscopy as potential method for diagnosis of dengue virus E-protein |
| title_full_unstemmed | Recent development of SPR spectroscopy as potential method for diagnosis of dengue virus E-protein |
| title_short | Recent development of SPR spectroscopy as potential method for diagnosis of dengue virus E-protein |
| title_sort | recent development of spr spectroscopy as potential method for diagnosis of dengue virus e-protein |
| url | http://psasir.upm.edu.my/id/eprint/73717/ http://psasir.upm.edu.my/id/eprint/73717/ http://psasir.upm.edu.my/id/eprint/73717/ http://psasir.upm.edu.my/id/eprint/73717/1/PROTEIN.pdf |