Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews
Background: Different diagnostic interviews are used as reference standards for major depression classification in research. Semi-structured interviews involve clinical judgement, whereas fully structured interviews are completely scripted. The Mini International Neuropsychiatric Interview (MINI), a...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2018
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| Online Access: | http://psasir.upm.edu.my/id/eprint/73642/ http://psasir.upm.edu.my/id/eprint/73642/1/Probability%20of%20major%20depression%20diagnostic%20classification%20using%20semi-structured%20versus%20fully%20structured%20diagnostic%20interviews.pdf |
| _version_ | 1848857324451528704 |
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| author | Levis, Brooke Benedetti, Andrea Riehm, Kira E. Saadat, Nazanin Levis, Alexander W. |
| author_facet | Levis, Brooke Benedetti, Andrea Riehm, Kira E. Saadat, Nazanin Levis, Alexander W. |
| author_sort | Levis, Brooke |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Background: Different diagnostic interviews are used as reference standards for major depression classification in research. Semi-structured interviews involve clinical judgement, whereas fully structured interviews are completely scripted. The Mini International Neuropsychiatric Interview (MINI), a brief fully structured interview, is also sometimes used. It is not known whether interview method is associated with probability of major depression classification.
Aims: To evaluate the association between interview method and odds of major depression classification, controlling for depressive symptom scores and participant characteristics.
Method: Data collected for an individual participant data meta-analysis of Patient Health Questionnaire-9 (PHQ-9) diagnostic accuracy were analyzed. Binomial Generalized Linear Mixed Models were fit.
Results: 17,158 participants (2,287 major depression cases) from 57 primary studies were analyzed. Among fully structured interviews, odds of major depression were higher for the MINI compared to the Composite International Diagnostic Interview (CIDI) [OR (95% CI) = 2.10 (1.15–3.87)]. Compared to semi-structured interviews, fully structured interviews (MINI
excluded) were non-significantly more likely to classify participants with low-level depressive
symptoms (PHQ-9 scores ≤6) as having major depression [OR (95% CI) = 3.13 (0.98–10.00)],
similarly likely for moderate-level symptoms (PHQ-9 scores 7–15) [OR (95% CI) = 0.96 (0.56–1.66)], and significantly less likely for high-level symptoms (PHQ-9 scores ≥16) [OR (95% CI) = 0.50 (0.26–0.97)]
Conclusions: The MINI may identify more depressed cases than the CIDI, and semi- and fully
structured interviews may not be interchangeable methods, but these results should be replicated. |
| first_indexed | 2025-11-15T11:55:44Z |
| format | Article |
| id | upm-73642 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:55:44Z |
| publishDate | 2018 |
| publisher | Cambridge University Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-736422022-03-03T03:06:48Z http://psasir.upm.edu.my/id/eprint/73642/ Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews Levis, Brooke Benedetti, Andrea Riehm, Kira E. Saadat, Nazanin Levis, Alexander W. Background: Different diagnostic interviews are used as reference standards for major depression classification in research. Semi-structured interviews involve clinical judgement, whereas fully structured interviews are completely scripted. The Mini International Neuropsychiatric Interview (MINI), a brief fully structured interview, is also sometimes used. It is not known whether interview method is associated with probability of major depression classification. Aims: To evaluate the association between interview method and odds of major depression classification, controlling for depressive symptom scores and participant characteristics. Method: Data collected for an individual participant data meta-analysis of Patient Health Questionnaire-9 (PHQ-9) diagnostic accuracy were analyzed. Binomial Generalized Linear Mixed Models were fit. Results: 17,158 participants (2,287 major depression cases) from 57 primary studies were analyzed. Among fully structured interviews, odds of major depression were higher for the MINI compared to the Composite International Diagnostic Interview (CIDI) [OR (95% CI) = 2.10 (1.15–3.87)]. Compared to semi-structured interviews, fully structured interviews (MINI excluded) were non-significantly more likely to classify participants with low-level depressive symptoms (PHQ-9 scores ≤6) as having major depression [OR (95% CI) = 3.13 (0.98–10.00)], similarly likely for moderate-level symptoms (PHQ-9 scores 7–15) [OR (95% CI) = 0.96 (0.56–1.66)], and significantly less likely for high-level symptoms (PHQ-9 scores ≥16) [OR (95% CI) = 0.50 (0.26–0.97)] Conclusions: The MINI may identify more depressed cases than the CIDI, and semi- and fully structured interviews may not be interchangeable methods, but these results should be replicated. Cambridge University Press 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/73642/1/Probability%20of%20major%20depression%20diagnostic%20classification%20using%20semi-structured%20versus%20fully%20structured%20diagnostic%20interviews.pdf Levis, Brooke and Benedetti, Andrea and Riehm, Kira E. and Saadat, Nazanin and Levis, Alexander W. (2018) Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews. British Journal of Psychiatry, 212 (6). 377 - 385. ISSN 0007-1250; ESSN: 1472-1465 https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/probability-of-major-depression-diagnostic-classification-using-semistructured-versus-fully-structured-diagnostic-interviews/C3EB93DB2EB50DE12D0C82F17A084CBC 10.1192/bjp.2018.54 |
| spellingShingle | Levis, Brooke Benedetti, Andrea Riehm, Kira E. Saadat, Nazanin Levis, Alexander W. Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews |
| title | Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews |
| title_full | Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews |
| title_fullStr | Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews |
| title_full_unstemmed | Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews |
| title_short | Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews |
| title_sort | probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews |
| url | http://psasir.upm.edu.my/id/eprint/73642/ http://psasir.upm.edu.my/id/eprint/73642/ http://psasir.upm.edu.my/id/eprint/73642/ http://psasir.upm.edu.my/id/eprint/73642/1/Probability%20of%20major%20depression%20diagnostic%20classification%20using%20semi-structured%20versus%20fully%20structured%20diagnostic%20interviews.pdf |