Fused multivariate empirical mode decomposition (MEMD) and inverse solution method for EEG source localization

EEG source localization is determining possible cortical sources of brain activities with scalp EEG. Generally, every step of the data processing sequence affects the accuracy of EEG source localization. In this paper, we introduce a fused multivariate empirical mode decomposing (MEMD) and inverse s...

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Main Authors: Khosropanah, Pegah, Ramli, Abdul Rahman, Lim, Kheng Seang, Marhaban, Mohammad Hamiruce, Ahmedov, Anvarjon
Format: Article
Language:English
Published: De Gruyter 2018
Online Access:http://psasir.upm.edu.my/id/eprint/72809/
http://psasir.upm.edu.my/id/eprint/72809/1/Fused%20multivariate%20empirical%20mode%20decomposition.pdf
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author Khosropanah, Pegah
Ramli, Abdul Rahman
Lim, Kheng Seang
Marhaban, Mohammad Hamiruce
Ahmedov, Anvarjon
author_facet Khosropanah, Pegah
Ramli, Abdul Rahman
Lim, Kheng Seang
Marhaban, Mohammad Hamiruce
Ahmedov, Anvarjon
author_sort Khosropanah, Pegah
building UPM Institutional Repository
collection Online Access
description EEG source localization is determining possible cortical sources of brain activities with scalp EEG. Generally, every step of the data processing sequence affects the accuracy of EEG source localization. In this paper, we introduce a fused multivariate empirical mode decomposing (MEMD) and inverse solution algorithm with an embedded unsupervised eye blink remover in order to localize the epileptogenic zone accurately. For this purpose, we constructed realistic forward models using MRI and boundary element method (BEM) for each patient to obtain results that are more realistic. We also developed an unsupervised algorithm utilizing a wavelet method to remove eye blink artifacts. Additionally, we applied MEMD, which is one of the recent and suitable feature extraction methods for non-linear, non-stationary, and multivariate signals such as EEG, to extract the signal of interest. We examined the localization results using the two most reliable linear distributed inverse methods in the literature: weighted minimum norm estimation (wMN) and standardized low resolution tomography (sLORETA). Results affirm the success of the proposed algorithm with the highest agreement compared to MRI reference by a specialist. Fusion of MEMD and sLORETA results in approximately zero localization error in terms of spatial difference with the validated MRI reference. High accuracy results of proposed algorithm using non-invasive and low-resolution EEG provide the potential of using this work for pre-surgical evaluation towards epileptogenic zone localization in clinics.
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spelling upm-728092021-02-11T11:12:59Z http://psasir.upm.edu.my/id/eprint/72809/ Fused multivariate empirical mode decomposition (MEMD) and inverse solution method for EEG source localization Khosropanah, Pegah Ramli, Abdul Rahman Lim, Kheng Seang Marhaban, Mohammad Hamiruce Ahmedov, Anvarjon EEG source localization is determining possible cortical sources of brain activities with scalp EEG. Generally, every step of the data processing sequence affects the accuracy of EEG source localization. In this paper, we introduce a fused multivariate empirical mode decomposing (MEMD) and inverse solution algorithm with an embedded unsupervised eye blink remover in order to localize the epileptogenic zone accurately. For this purpose, we constructed realistic forward models using MRI and boundary element method (BEM) for each patient to obtain results that are more realistic. We also developed an unsupervised algorithm utilizing a wavelet method to remove eye blink artifacts. Additionally, we applied MEMD, which is one of the recent and suitable feature extraction methods for non-linear, non-stationary, and multivariate signals such as EEG, to extract the signal of interest. We examined the localization results using the two most reliable linear distributed inverse methods in the literature: weighted minimum norm estimation (wMN) and standardized low resolution tomography (sLORETA). Results affirm the success of the proposed algorithm with the highest agreement compared to MRI reference by a specialist. Fusion of MEMD and sLORETA results in approximately zero localization error in terms of spatial difference with the validated MRI reference. High accuracy results of proposed algorithm using non-invasive and low-resolution EEG provide the potential of using this work for pre-surgical evaluation towards epileptogenic zone localization in clinics. De Gruyter 2018-07 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/72809/1/Fused%20multivariate%20empirical%20mode%20decomposition.pdf Khosropanah, Pegah and Ramli, Abdul Rahman and Lim, Kheng Seang and Marhaban, Mohammad Hamiruce and Ahmedov, Anvarjon (2018) Fused multivariate empirical mode decomposition (MEMD) and inverse solution method for EEG source localization. Biomedical Engineering-Biomedizinische Technik, 63 (4). 467 - 479. ISSN 0013-5585; ESSN: 1862-278X https://pubmed.ncbi.nlm.nih.gov/28734112/ 10.1515/bmt-2017-0011
spellingShingle Khosropanah, Pegah
Ramli, Abdul Rahman
Lim, Kheng Seang
Marhaban, Mohammad Hamiruce
Ahmedov, Anvarjon
Fused multivariate empirical mode decomposition (MEMD) and inverse solution method for EEG source localization
title Fused multivariate empirical mode decomposition (MEMD) and inverse solution method for EEG source localization
title_full Fused multivariate empirical mode decomposition (MEMD) and inverse solution method for EEG source localization
title_fullStr Fused multivariate empirical mode decomposition (MEMD) and inverse solution method for EEG source localization
title_full_unstemmed Fused multivariate empirical mode decomposition (MEMD) and inverse solution method for EEG source localization
title_short Fused multivariate empirical mode decomposition (MEMD) and inverse solution method for EEG source localization
title_sort fused multivariate empirical mode decomposition (memd) and inverse solution method for eeg source localization
url http://psasir.upm.edu.my/id/eprint/72809/
http://psasir.upm.edu.my/id/eprint/72809/
http://psasir.upm.edu.my/id/eprint/72809/
http://psasir.upm.edu.my/id/eprint/72809/1/Fused%20multivariate%20empirical%20mode%20decomposition.pdf