Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide
In this study, a methanolic extract derived from a marine organism was investigated for the effect on the growth of MRSA resistant to b-lactam antibiotics. The nucleotide sequence changes of essential genes inclusive of mecA, mecR1, 16sRNA, mprF and msR of the inhibited MRSA strains were determined...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2007
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| Online Access: | http://psasir.upm.edu.my/id/eprint/7269/ |
| _version_ | 1848840548573511680 |
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| author | Shamsudin, M. Mohamed Alipiah, Norfarrah Neela, Vasantha Kumari Md Yusoff, Fatimah Arshad, Aziz |
| author_facet | Shamsudin, M. Mohamed Alipiah, Norfarrah Neela, Vasantha Kumari Md Yusoff, Fatimah Arshad, Aziz |
| author_sort | Shamsudin, M. |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | In this study, a methanolic extract derived from a marine
organism was investigated for the effect on the growth of MRSA resistant to b-lactam antibiotics. The nucleotide sequence changes of essential genes inclusive of mecA, mecR1, 16sRNA, mprF and msR of the inhibited MRSA strains were determined. A potential antibacterial peptide with activity on permeabilising the membrane of MRSA strains
was investigated through a cellular bioassay. |
| first_indexed | 2025-11-15T07:29:06Z |
| format | Article |
| id | upm-7269 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T07:29:06Z |
| publishDate | 2007 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-72692010-07-30T04:27:44Z http://psasir.upm.edu.my/id/eprint/7269/ Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide Shamsudin, M. Mohamed Alipiah, Norfarrah Neela, Vasantha Kumari Md Yusoff, Fatimah Arshad, Aziz In this study, a methanolic extract derived from a marine organism was investigated for the effect on the growth of MRSA resistant to b-lactam antibiotics. The nucleotide sequence changes of essential genes inclusive of mecA, mecR1, 16sRNA, mprF and msR of the inhibited MRSA strains were determined. A potential antibacterial peptide with activity on permeabilising the membrane of MRSA strains was investigated through a cellular bioassay. Elsevier 2007 Article PeerReviewed Shamsudin, M. and Mohamed Alipiah, Norfarrah and Neela, Vasantha Kumari and Md Yusoff, Fatimah and Arshad, Aziz (2007) Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide. International Journal of Antimicrobial Agents, 29 (suppl.2). S634. ISSN 0924-8579 http://dx.doi.org/10.1016/S0924-8579(07)72030-7 English |
| spellingShingle | Shamsudin, M. Mohamed Alipiah, Norfarrah Neela, Vasantha Kumari Md Yusoff, Fatimah Arshad, Aziz Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide |
| title | Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide |
| title_full | Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide |
| title_fullStr | Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide |
| title_full_unstemmed | Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide |
| title_short | Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide |
| title_sort | analysis of essential gene changes in mrsa and non-mrsa strains inhibited by methanolic extract correlated to membrane permeabilising peptide |
| url | http://psasir.upm.edu.my/id/eprint/7269/ http://psasir.upm.edu.my/id/eprint/7269/ |