Curcumin derivative, 2,6-bis(2-fluorobenzylidene)cyclohexanone (MS65) inhibits interleukin-6 production through suppression of NF-κB and MAPK pathways in histamine-induced human keratinocytes cell (HaCaT)

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Curcumin derivative, 2,6-bis(2-fluorobenzylidene)cyclohexanone (MS65) inhibits interleukin-6 production through suppression of NF-κB and MAPK pathways in histamine-induced human keratinocytes cell (HaCaT)

Background: Histamine is a well-known mediator involved in skin allergic responses through up-regulation of pro-inflammatory cytokines. Antihistamines remain the mainstay of allergy treatment, but they were found limited in efficacy and associated with several common side effects. Therefore, alterna...

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Bibliographic Details
Main Authors:	Razali, Nurul Atika, Nazarudin, Nur Amiza, Lai, Kok Song, Abas, Faridah, Ahmad, Syahida
Format:	Article
Language:	English
Published:	BioMed Central 2018
Online Access:	http://psasir.upm.edu.my/id/eprint/72155/ http://psasir.upm.edu.my/id/eprint/72155/1/Curcumin%20derivative.pdf

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