Modelling the influence of ligand binding towards the structure and dynamics of protein arginine deiminase IV

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Modelling the influence of ligand binding towards the structure and dynamics of protein arginine deiminase IV

An enzyme called Protein Arginine Deiminase IV (PAD4) has gained tremendous attention due to its role in rheumatoid arthritis (RA). It catalyses the citrullination reaction, whose products was reported to be dysregulated in the RA patients. Therefore, modulation of PAD4 activities is considered as a...

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Bibliographic Details
Main Author:	Ibrahim, Zalikha
Format:	Thesis
Language:	English
Published:	2017
Subjects:	Ligand binding (Biochemistry) Arginine Proteins
Online Access:	http://psasir.upm.edu.my/id/eprint/71030/ http://psasir.upm.edu.my/id/eprint/71030/1/FS%202017%2082%20-%20IR%2843%29edited.pdf

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