CpG-free plasmid DNA exhibits limited in vitro reporter gene expression due to transcriptional incongruity
The use of efficient vector is essential in gene therapy, which has the promising potential to treat not only genetic diseases but also acquired diseases. Although plasmid DNAs (pDNA) have been shown to be a much safer alternative compared to viral vectors, limitations, like detrimental inflammatory...
| Main Author: | Habib Rahuman, Muhammad Omar |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2017
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/70927/ http://psasir.upm.edu.my/id/eprint/70927/1/FPSK%28M%29%202017%2010%20-%20IR.pdf |
Similar Items
Limited expression of non-integrating CpG-free plasmid is associated with increased nucleosome enrichment
by: Habib, Omar, et al.
Published: (2020)
by: Habib, Omar, et al.
Published: (2020)
CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.
by: Hyde, Stephen C., et al.
Published: (2008)
by: Hyde, Stephen C., et al.
Published: (2008)
Effects of CpG islands DNA methylation on the human choline kinase alpha promoter activity
by: Sa'dom, Siti Aisyah Faten Mohamed
Published: (2021)
by: Sa'dom, Siti Aisyah Faten Mohamed
Published: (2021)
Transgene expression from CpG-reduced lentiviral gene delivery vectors in vitro
by: Low, Poh Tee, et al.
Published: (2014)
by: Low, Poh Tee, et al.
Published: (2014)
Differential patterns of methylation of the IFN promoter at CpG and non-CpG sites underlie differences in IFN gene expression between human neonatal and adult CD45RO- T-cells
by: White, Greg, et al.
Published: (2002)
by: White, Greg, et al.
Published: (2002)
Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia.
by: Roels, Juliette, et al.
Published: (2020)
by: Roels, Juliette, et al.
Published: (2020)
Testing the FMR1 promoter for mosaicism in DNA methylation among CpG sites, strands, and cells in FMR1-expressing males with fragile X syndrome
by: Stöger, Reinhard, et al.
Published: (2011)
by: Stöger, Reinhard, et al.
Published: (2011)
CpG Methylation patterns in the IFN promoter in naive T cells: Variations during Th1 and Th2 differentiation and between atopics and non-atopics
by: White, Greg, et al.
Published: (2006)
by: White, Greg, et al.
Published: (2006)
The effect of budesonide and 5-azacytidine on the levels of methylation at the CpG islands of human choline kinase alpha (ckα) and beta (ckβ) promoter
by: Rahman, Muhammad Al Bunyamin Abdul
Published: (2017)
by: Rahman, Muhammad Al Bunyamin Abdul
Published: (2017)
Purification of transcriptionally active multimeric plasmid DNA using zwitterionic detergent and carbonate apatite nano-particles.
by: Lau, Khye Tee, et al.
Published: (2011)
by: Lau, Khye Tee, et al.
Published: (2011)
Method for preparing plasmid DNA
by: Mohamed, Farahidah, et al.
Published: (2015)
by: Mohamed, Farahidah, et al.
Published: (2015)
Incongruent restricted disjoint covering systems
by: Myerson, G., et al.
Published: (2009)
by: Myerson, G., et al.
Published: (2009)
Removal of endotoxins from plasmid DNA: Analysis of aggregative interaction of mobile divalent metal cations with endotoxins and plasmid DNA
by: Ongkudon, C., et al.
Published: (2012)
by: Ongkudon, C., et al.
Published: (2012)
DNA free CRISPR/DCAS9 based transcriptional activation system for UGT76G1 gene in Stevia rebaudiana Bertoni protoplasts
by: Ghose, Asish Kumar, et al.
Published: (2022)
by: Ghose, Asish Kumar, et al.
Published: (2022)
Turning to the Visitor's Body: Affective Exhibition and the Limits of Representation
by: Harris, Jennifer
Published: (2012)
by: Harris, Jennifer
Published: (2012)
Inferring Kangaroo Phylogeny from Incongruent Nuclearand Mitochondrial Genes
by: Phillips, M., et al.
Published: (2013)
by: Phillips, M., et al.
Published: (2013)
Successful transfer of plasmid DNA into in vitro cells transfected with an inorganic plasmidMg/Al-LDH nanobiocomposite material as a vector for gene expression
by: Masarudin, Mas Jaffri, et al.
Published: (2009)
by: Masarudin, Mas Jaffri, et al.
Published: (2009)
A chloroplast DNA (cpDNA) extraction protocol for diversity analysis of oil palm (Elaeis sp.)
by: Ho, Carl Miew, et al.
Published: (2015)
by: Ho, Carl Miew, et al.
Published: (2015)
Interfacial partition of plasmid DNA in aqueous two-phase systems
by: Luechau, Frank, et al.
Published: (2009)
by: Luechau, Frank, et al.
Published: (2009)
Cellulose acetate phthalate microencapsulation and delivery of plasmid DNA to the intestines
by: Hanafi, Aimi Melati, et al.
Published: (2013)
by: Hanafi, Aimi Melati, et al.
Published: (2013)
Ironic effect on emotional response and attitude: moderating role of incongruity degree.
by: Gu, junwen
Published: (2020)
by: Gu, junwen
Published: (2020)
The psycho-medical case against a gender incongruence of childhood diagnosis
by: Winter, Sam, et al.
Published: (2016)
by: Winter, Sam, et al.
Published: (2016)
Ironic effect on emotional response and attitude: moderating role of incongruity degree.
by: Gu, Junwen
Published: (2020)
by: Gu, Junwen
Published: (2020)
Incongruence of gender, leadership roles and underrepresentation of women in sport leadership positions
by: Aman, Mirian Pabatao, et al.
Published: (2016)
by: Aman, Mirian Pabatao, et al.
Published: (2016)
Incongruence of gender, leadership roles and underrepresentation of women in sport leadership positions
by: Aman, Mirian Pabatao
Published: (2019)
by: Aman, Mirian Pabatao
Published: (2019)
CPG-based control system for flexible snake robot locomotion
by: Khan, Md. Raisuddin, et al.
Published: (2014)
by: Khan, Md. Raisuddin, et al.
Published: (2014)
Integrated cathodic protection (CP) sensor network development of the CP sensor
by: Wold, K., et al.
Published: (2018)
by: Wold, K., et al.
Published: (2018)
Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator
by: Rajasekar, Karthik V., et al.
Published: (2016)
by: Rajasekar, Karthik V., et al.
Published: (2016)
Endotoxin removal and plasmid DNA recovery in various metal ion solutions
by: Ongkudon, C., et al.
Published: (2011)
by: Ongkudon, C., et al.
Published: (2011)
Gene transfer into the lung by nanoparticle dextran-spermine/plasmid DNA complexes.
by: Abdullah, Syahrilnizam, et al.
Published: (2010)
by: Abdullah, Syahrilnizam, et al.
Published: (2010)
Partition of plasmid DNA in polymer-salt aqueous two phase systems
by: Luechau, Frank, et al.
Published: (2009)
by: Luechau, Frank, et al.
Published: (2009)
Synthesis and characterization of chitosan-saponin nanoparticle for application in plasmid DNA delivery
by: Bande, Faruku, et al.
Published: (2015)
by: Bande, Faruku, et al.
Published: (2015)
Role incongruity and prejudice: barriers in Malay Muslim women managers’ career experiences
by: Rossenkhan, Zubeida, et al.
Published: (2024)
by: Rossenkhan, Zubeida, et al.
Published: (2024)
Interplay between DNA replication, transcription and repair
by: Trautinger, Brigitte W.
Published: (2002)
by: Trautinger, Brigitte W.
Published: (2002)
Co-encapsulation of NIgella sativa oil with plasmid DNA into biodegradable PLGA nanoparticle
by: Doolaane, Abd Monem, et al.
Published: (2013)
by: Doolaane, Abd Monem, et al.
Published: (2013)
In vivo evaluation of microencapsulated bicistronic plasmid DNA vaccine against Vibrio cholerae
by: Ahmad Zamri, Najwa
Published: (2021)
by: Ahmad Zamri, Najwa
Published: (2021)
Incongruity between pedagogy of authenticity and contemporary educational apparatus: person-centred phenomenological studies
by: Plust, Urszula
Published: (2023)
by: Plust, Urszula
Published: (2023)
Bio-inspired snake robot locomotion: a CPG-based control approach
by: Billah, Md. Masum, et al.
Published: (2015)
by: Billah, Md. Masum, et al.
Published: (2015)
Classification Of Cpg Island And Promoter Regions Using Rare K-Mer Motifs
by: Mohamed Hashim, Ezzeddin Kamil
Published: (2015)
by: Mohamed Hashim, Ezzeddin Kamil
Published: (2015)
Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker
by: Heap, John T., et al.
Published: (2012)
by: Heap, John T., et al.
Published: (2012)
Similar Items
-
Limited expression of non-integrating CpG-free plasmid is associated with increased nucleosome enrichment
by: Habib, Omar, et al.
Published: (2020) -
CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.
by: Hyde, Stephen C., et al.
Published: (2008) -
Effects of CpG islands DNA methylation on the human choline kinase alpha promoter activity
by: Sa'dom, Siti Aisyah Faten Mohamed
Published: (2021) -
Transgene expression from CpG-reduced lentiviral gene delivery vectors in vitro
by: Low, Poh Tee, et al.
Published: (2014) -
Differential patterns of methylation of the IFN promoter at CpG and non-CpG sites underlie differences in IFN gene expression between human neonatal and adult CD45RO- T-cells
by: White, Greg, et al.
Published: (2002)