Airway remodeling blockade with an orally active geranyl acetophenone

QR Code

Airway remodeling blockade with an orally active geranyl acetophenone

n the last few decades, structural changes of airways in asthma has gained huge attention from both clinicians and scientists as current therapeutic approaches are inadequate in attenuating airway remodeling, especially in severe asthma patients. Airway remodeling includes subepithelial fibrosis, th...

Full description

Bibliographic Details
Main Author:	Lee, Yu Zhao
Format:	Thesis
Language:	English
Published:	2017
Subjects:	Asthma - physiopathology Respiratory System Airway Obstruction
Online Access:	http://psasir.upm.edu.my/id/eprint/70696/ http://psasir.upm.edu.my/id/eprint/70696/1/FPSK%28P%29%202017%2022%20-%20IR.pdf

Similar Items

Mathematical Models of Pro-remodelling Growth Factor Activation in Asthmatic Airways
by: Pybus, Hannah J.
Published: (2020)

An in vitro and in silico study of altered airway smooth muscle structure and function in a remodelled asthmatic airway
by: Brown, Sarah
Published: (2023)

Matrix metalloproteinase-1 mediated extra-cellular matrix remodelling contributes to airway smooth muscle growth and asthma severity
by: Naveed, Shams-un-nisa
Published: (2018)

Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthma
by: Donovan, G.M., et al.
Published: (2020)

MMP-1 activation contributes to airway smooth muscle growth and asthma severity
by: Naveed, Shams-un-nisa, et al.
Published: (2017)

Burden of disease and benefits of exercise in fixed airway obstruction asthma
by: Turner, Sian Elizabeth
Published: (2009)

Ochrobactrum anthropi induced retropharyngeal abscess with mediastinal extension complicating airway obstruction: A case report.
by: Al-naami, A., et al.
Published: (2014)

Blockade of eosinophil-induced bronchial epithelial-mesenchymal transition with a geranyl acetophenone in a coculture model
by: Lee, Yu Zhao, et al.
Published: (2017)

Effects of 2,4,6-trihydroxy-3-geranyl acetophenone on growth factor-induced human bronchial smooth muscle cell proliferation in asthma
by: Yap, Hui Min
Published: (2018)

A prebiotic galactooligosaccharide mixture reduces severity of hyperpnoea-induced bronchoconstriction and markers of airway inflammation
by: Williams, Neil C., et al.
Published: (2016)

The differential effects of azithromycin on the airway epithelium in vitro and in vivo
by: Slater, Mariel, et al.
Published: (2016)

In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss
by: Chernyavsky, Igor L., et al.
Published: (2018)

Developing platforms for tissue engineering of the airways
by: Ramis, Jopeth
Published: (2020)

Aberrant DNA methylation and its regulation of gene expression in airway smooth muscle cells of individuals with asthma
by: Clifford, Rachel Louise
Published: (2023)

Prevalence, clinico-epidemiological characteristics and risk factors of intestinal microsporidiosis in children with malignancy in the Institute of Pediatric, Kuala Lumpur, Malaysia
by: Ithnin, Nur Raihana
Published: (2013)

Modelling cell–matrix interactions in airway smooth muscle cells
by: Irons, Linda
Published: (2019)

The role of histone arginine methylation in cytokine/chemokine gene expression in airway smooth muscle cells in asthma
by: Kaczmarek, Klaudia
Published: (2019)

The use of non-bronchoscopic brushings to study the paediatric airway
by: Lane, C., et al.
Published: (2005)

Indoor air pollutants in schools and their relationship with airway inflammation, respiratory and allergic symptoms among school children in Hulu Langat, Malaysia
by: Mohd Isa, Khairul Nizam
Published: (2021)

Effect of cigarette smoke extract on inflammatory cytokine production and corticosteroid insensitivity in human airway smooth muscle cells
by: Alahmari, Mushabbab
Published: (2022)

Investigating the symptoms of airways disease
by: Martin, Matthew J.
Published: (2017)

Utility of the precision cut lung slice model to investigate airway smooth muscle contraction
by: Fox, Jane
Published: (2011)

Comparison of techniques for obtaining lower airway epithelial cells from children
by: McNamara, P.S., et al.
Published: (2008)

URO protective effect of Luteolin Nano Suspension on Cyclophosphamide-Induced Hemorrhagic Cystitis in rats
by: Harikumar, Ravindran Pillai
Published: (2016)

Effect of the velopharynx on intraluminal pressures in reconstructed pharynges derived from individuals with and without sleep apnea
by: Cisonni, Julien, et al.
Published: (2013)

Regulation of ige-mediated mast cell degranulation in allergy by geranyl acetophenone
by: Tan, Ji Wei
Published: (2017)

Oral and topical administration of a geranyl acetophenone attenuates DNCB-induced atopic dermatitis-like skin lesions in BALB/c mice
by: Mohd Kasim, Vivi Nur Khalieda, et al.
Published: (2024)

Oral and topical administration of a geranyl acetophenone attenuates DNCB‑induced atopic dermatitis‑like skin lesions in BALB/c mice
by: Mohd Kasim, Vivi Nur Khalieda, et al.
Published: (2024)

Assessing the unified airway hypothesis in children via transcriptional profiling of the airway epithelium
by: Kicic, Anthony, et al.
Published: (2020)

Confounding effects of gavage in mice: Impaired respiratory structure and function
by: Larcombe, Alexander, et al.
Published: (2019)

Peripheral killer cells do not differentiate between asthma patients with or without fixed airway obstruction
by: Tubby, Carolyn, et al.
Published: (2016)

Characterization of candidate proteins involved in calreticulin-dependent invasion using breast cancer tissue biopsies
by: Noudehi, Zahra Yekta Moghaddam
Published: (2012)

GEOGENIC DUST IMPACTS CELL VIABILITY AND INFLAMMATORY CYTOKINES IN HUMAN AIRWAY EPITHELIAL CELLS
by: Clifford, H., et al.
Published: (2014)

In vitro airway epithelial cell models differ in their functional response to neutrophil elastase exposure
by: Garratt, L., et al.
Published: (2013)

CULTURING SUCCESS OF CF AIRWAY EPITHELIAL CELLS (AEC) IS ASSOCIATED WITH DISEASE SPECIFIC FACTORS
by: Garratt, L., et al.
Published: (2013)

The effects of endocannabinoids and phytocannabinoids on bronchial epithelial permeability
by: Shang, Valerie C.M.
Published: (2016)

DYSREGULATED REPAIR AND EPITHELIAL INJURY IN SMALL AND LARGE AIRWAYS OF LUNG TRANSPLANT PATIENTS IS AMELIORATED BY AZITHROMYCIN
by: Kicic, Anthony, et al.
Published: (2014)

BIODIESEL EXHAUST INDUCED CYTOTOXICITY AND PRO-INFLAMMATORY MEDIATOR PRODUCTION IN HEALTHY HUMAN AIRWAY EPITHELIAL CELLS
by: Larcombe, A., et al.
Published: (2014)

Investigating a role for heterotrimeric G-proteins in activating TGFβ in asthma
by: Middlewick, Robert James
Published: (2020)

HUMAN RHINOVIRUS INFECTION OF ASTHMATIC AIRWAY EPITHELIAL CELLS CAUSES TIGHT JUNCTION DISASSEMBLY RESULTING IN INCREASED PERMEABILITY
by: Looi, K., et al.
Published: (2013)