Mechanisms of interferon-gamma (IFN-y)-induced hyperpermeability changes in human umbilical vein endothelial cells

QR Code

Mechanisms of interferon-gamma (IFN-y)-induced hyperpermeability changes in human umbilical vein endothelial cells

Endothelial dysfunction, characterized by increased endothelial permeability, is the initiating step in the pathogenesis of vascular diseases such as atherosclerosis. Interferon-gamma (IFN-γ), a pro-inflammatory cytokine, has been reported to impair the endothelial barrier and thus, increases vascul...

Full description

Bibliographic Details
Main Author:	Ng, Chin Theng
Format:	Thesis
Language:	English
Published:	2017
Subjects:	Endothelial Cells
Online Access:	http://psasir.upm.edu.my/id/eprint/70621/ http://psasir.upm.edu.my/id/eprint/70621/1/FPSK%28P%29%202017%209%20-%20IR.pdf

Similar Items

Properties of asiaticoside in suppressing hyperpermeability in human umbilical vein endothelial cells induced by interferon-gamma
by: Khairudin, Nurnabila Huda
Published: (2016)

Effects of omentin on endothelial disruption and hydrogen peroxide-induced inflammation in vascular endothelial cell monolayer
by: Kamaruddin, Nur Aqilah
Published: (2022)

In vitro protective effects of 2,4,6-trihydroxy-3-geranyl acetophenone on junctional protein disruption and the underlying signaling pathways in lipopolysaccharide-induced endothelial hyperpermeability
by: Chan, Yee Han
Published: (2022)

Varying magnesium concentration elicits changes in inflammatory response in human umbilical vein endothelial cells (HUVECs)
by: Almousa, Lujain A., et al.
Published: (2018)

Dynamics of cytokine induced E-selectin expression in endothelial cells
by: Ogrodzinski, Lydia
Published: (2023)

The Effect of Carbon Disulfide on Oxidative Injury in Vein Endothelial Cells
by: Chen, S., et al.
Published: (2006)

In vitro anti-atherogenic effects of asiatic acid in human aortic endothelial cells
by: Fong, Lai Yen
Published: (2016)

Interferon-gamma (IFN-γ): reviewing its mechanisms and signaling pathways on the regulation of endothelial barrier function
by: Ng, Chin Theng, et al.
Published: (2023)

Identification of long non-coding RNAs in serum exosomes from colorectal cancer patients and effects of exosomes on tube formation by endothelial cells
by: Ng, Chin Tat
Published: (2019)

The relationship between in-vitro endothelial permeability and molecules of the intercellular junction
by: Budworth, Rachel Ann
Published: (2003)

Malaysian Tualang honey inhibits hydrogen peroxide-induced endothelial hyperpermeability
by: Devasvaran, Kogilavanee, et al.
Published: (2019)

Expression profiling of genes related to endothelial cell function in pre-diabetes and type 2 diabetes subjects
by: Moradipoor, Sara
Published: (2016)

Asiaticoside inhibits TNF-alpha-induced endothelial hyperpermeability of human aortic endothelial cells
by: Lai, Yen Fong, et al.
Published: (2015)

Transendothelial migration of human umbilical mesenchymal stem cells across uterine endothelial monolayers: junctional dynamics and putative mechanisms
by: Ebrahim, Neven A., et al.
Published: (2016)

Experimental review on the Substance P-enhanced endothelial permeability in human umbilical vein endothelial cells (HUVECS)
by: N. N. H., Khairudin, et al.
Published: (2017)

The effect of gestational diabetes on human umbilical mesenchymal stem cells and their ability to influence endothelial permeability
by: Salem, Samar
Published: (2023)

Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt the vascular maturation in infantile haemangioma
by: Ye, Xi, et al.
Published: (2016)

Cellular and molecular mechanisms underlying extravasation of human Wharton’s jelly mesenchymal stem cells across fetal and adult endothelial cell monolayers
by: Ebrahim, Neven
Published: (2016)

The role of outgrowth endothelial cells as therapeutics for ischaemic injury-mediated cerebrovascular damage: impact of NOX2 inhibitor
by: Alwjwaj, Mansour
Published: (2022)

Expression profiling of genes related to endothelial cells biology in patients with type 2 diabetes and patients with pre-diabetes
by: Moradipoor, Sara, et al.
Published: (2016)

Vitexin promotes nitric oxide production in human umbilical vein endothelial cells
by: Azizah Ugusman,, et al.
Published: (2025)

Identification of genes and pathways regulated by the PRH/HHEX transcription factor in endothelial and lymphatic cells
by: Dahhan, Rania
Published: (2024)

Biphasic effects of autophagy on decompression bubble-induced endothelial injury
by: Wang, M., et al.
Published: (2019)

The impacts of endothelial cell senescence on ageing-related blood-brain barrier dysfunction and the potential therapeutic strategies
by: Ya, Jingyuan
Published: (2025)

Pre-eclampsia: the role of vascular endothelial growth factor and its interaction with the vascular endothelium
by: Brockelsby, Jeremy Charles
Published: (2001)

Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain
by: Ved, Nikita, et al.
Published: (2018)

Isolation methods and culture conditions of human umbilical vein endothelial cells from Malaysian women
by: Raja Nor Suhaila,, et al.
Published: (2017)

Anti-angiogenic effect of Ardisia crispa root in human umbilical vein endothelial cells (HUVECS)
by: Lim, Wen Jun, et al.
Published: (2015)

The diverse effects of substance P on brain microvascular endothelial cells and related molecular mechanism
by: Gao, Xin
Published: (2024)

Temporal studies into attachment, VE-cadherin perturbation, and paracellular migration of human umbilical mesenchymal stem cells across umbilical vein endothelial monolayers
by: Ebrahim, Neven A., et al.
Published: (2015)

Development of a human induced pluripotent stem cells (hiPSCs)-derived, universal platform, for generation of immunocompetent multi-tissue organoids
by: Azis, Rizal
Published: (2024)

Blood-Brain Barrier on-a-chip model for the study of drug permeability into the brain
by: Whitehouse, Chloe Ann
Published: (2022)

Bixa orellana leaf extract suppress histamine-induced endothelial hyperpermeability via the PLC-NO-cGMP signaling cascade
by: Yong, Yoke Keong, et al.
Published: (2015)

Effect of FGF-2 and PDGF-BB on a co-culture of human gingival fibroblasts and umbilical vein endothelial cells
by: Min Allah, Nasar Um, et al.
Published: (2020)

Effect of fibroblast and platelet-derived growth factors on co-culture of human gingival fibroblasts and umbilical vein endothelial cells
by: Allah, Nasar Um Min
Published: (2018)

Osteocalcin and the vasculature
by: Millar, Sophie
Published: (2020)

Methicillin resistant Staphylococcus aureus adhesion to human umbilical vein endothelial cells demonstrates wall shear stress dependent behaviour
by: Viegas, K., et al.
Published: (2011)

Antioxidants attenuate hyperglycaemia-mediated brain endothelial cell dysfunction and blood–brain barrier hyperpermeability
by: Allen, C.L., et al.
Published: (2009)

Antioxidant properties of aqueous and methanol extract from Tinospora crispa and its ability to Attenuate Hydrogen Peroxide-induced stress injury in human umbilical Vein Endothelial cells.
by: S.K., Ihsan, et al.
Published: (2011)

Non-viral transfection of bone marrow-derived mesenchymal stem cell with human interferon-gamma gene and in vitro efficiency against chronic myeloid leukaemia cells
by: Liew, Lee Chuen
Published: (2013)