Identification of Phosphoprotien : Phosphoprotien and Phosphoprotien : Nucleocapsid Protein Interaction Domains of New Castle Disease Virus

Summary : The yeast two hybrid system has been used to identify domains of the Newcastle disease virus ( NDV ) phosphoprotien (P) involved in self –association and interaction with the nucleocapsid protein (NP). Deletion analysis was used to map the domain (s) of the P protein involved in P:P and P...

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Main Authors: Jahanshiri, Fatemeh, Eshaghi, Majid, Yusoff, Khatijah
Format: Article
Language:English
English
Published: Springer Wien 2004
Online Access:http://psasir.upm.edu.my/id/eprint/696/
http://psasir.upm.edu.my/id/eprint/696/1/Identification%20of%20Phosphoprotien.pdf
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author Jahanshiri, Fatemeh
Eshaghi, Majid
Yusoff, Khatijah
author_facet Jahanshiri, Fatemeh
Eshaghi, Majid
Yusoff, Khatijah
author_sort Jahanshiri, Fatemeh
building UPM Institutional Repository
collection Online Access
description Summary : The yeast two hybrid system has been used to identify domains of the Newcastle disease virus ( NDV ) phosphoprotien (P) involved in self –association and interaction with the nucleocapsid protein (NP). Deletion analysis was used to map the domain (s) of the P protein involved in P:P and P:NP interactions. The C- terminal 45 amino acids (residues 247-291) were shown to play a major role in both of interaction. Comparison of these finding with other report suggests that paramyxoviruses are different with respect to interaction domain(s) between these two essential viral proteins involved in genome replication.
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institution Universiti Putra Malaysia
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language English
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publishDate 2004
publisher Springer Wien
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spelling upm-6962015-10-21T00:40:00Z http://psasir.upm.edu.my/id/eprint/696/ Identification of Phosphoprotien : Phosphoprotien and Phosphoprotien : Nucleocapsid Protein Interaction Domains of New Castle Disease Virus Jahanshiri, Fatemeh Eshaghi, Majid Yusoff, Khatijah Summary : The yeast two hybrid system has been used to identify domains of the Newcastle disease virus ( NDV ) phosphoprotien (P) involved in self –association and interaction with the nucleocapsid protein (NP). Deletion analysis was used to map the domain (s) of the P protein involved in P:P and P:NP interactions. The C- terminal 45 amino acids (residues 247-291) were shown to play a major role in both of interaction. Comparison of these finding with other report suggests that paramyxoviruses are different with respect to interaction domain(s) between these two essential viral proteins involved in genome replication. Springer Wien 2004 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/696/1/Identification%20of%20Phosphoprotien.pdf Jahanshiri, Fatemeh and Eshaghi, Majid and Yusoff, Khatijah (2004) Identification of Phosphoprotien : Phosphoprotien and Phosphoprotien : Nucleocapsid Protein Interaction Domains of New Castle Disease Virus. Archives of Virology, 150 (3). pp. 611-618. ISSN 0304-8608 http://dx.doi.org/10.1007/s00705-004-0439-z English
spellingShingle Jahanshiri, Fatemeh
Eshaghi, Majid
Yusoff, Khatijah
Identification of Phosphoprotien : Phosphoprotien and Phosphoprotien : Nucleocapsid Protein Interaction Domains of New Castle Disease Virus
title Identification of Phosphoprotien : Phosphoprotien and Phosphoprotien : Nucleocapsid Protein Interaction Domains of New Castle Disease Virus
title_full Identification of Phosphoprotien : Phosphoprotien and Phosphoprotien : Nucleocapsid Protein Interaction Domains of New Castle Disease Virus
title_fullStr Identification of Phosphoprotien : Phosphoprotien and Phosphoprotien : Nucleocapsid Protein Interaction Domains of New Castle Disease Virus
title_full_unstemmed Identification of Phosphoprotien : Phosphoprotien and Phosphoprotien : Nucleocapsid Protein Interaction Domains of New Castle Disease Virus
title_short Identification of Phosphoprotien : Phosphoprotien and Phosphoprotien : Nucleocapsid Protein Interaction Domains of New Castle Disease Virus
title_sort identification of phosphoprotien : phosphoprotien and phosphoprotien : nucleocapsid protein interaction domains of new castle disease virus
url http://psasir.upm.edu.my/id/eprint/696/
http://psasir.upm.edu.my/id/eprint/696/
http://psasir.upm.edu.my/id/eprint/696/1/Identification%20of%20Phosphoprotien.pdf