Rare occurrence of type lll membranoproliferative glomerulonephritis in a patient with hepatitis C in sustained virologic response phase

Hepatitis C virus (HCV) infection is known to cause acute and chronic active hepatitis. In addition, HCV also has systemic disorder involvement that links to various extra-hepatic complications. We report a case of a patient which has been diagnosed to have Hepatitis C Genotype 3A who has been start...

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Main Authors: Tan, Yi Jun, Then, Ru Fah, Lim, Christopher Thiam Seong
Format: Article
Language:English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019
Online Access:http://psasir.upm.edu.my/id/eprint/69561/
http://psasir.upm.edu.my/id/eprint/69561/1/2019060311385920_MJMHS_June_2019.pdf
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author Tan, Yi Jun
Then, Ru Fah
Lim, Christopher Thiam Seong
author_facet Tan, Yi Jun
Then, Ru Fah
Lim, Christopher Thiam Seong
author_sort Tan, Yi Jun
building UPM Institutional Repository
collection Online Access
description Hepatitis C virus (HCV) infection is known to cause acute and chronic active hepatitis. In addition, HCV also has systemic disorder involvement that links to various extra-hepatic complications. We report a case of a patient which has been diagnosed to have Hepatitis C Genotype 3A who has been started on antiviral. He achieved end treatment response and sustained virologic response. During routine follow up, he experienced acute kidney injury. Renal biopsy showed type III membranoproliferative glomerulonephritis. His proteinuria improved greatly with the addition of angiotensin converting enzyme inhibitor. This case highlights the possibility of appearance of HCV related glomerulonephritis in patient who has sustained virological response.
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spelling upm-695612019-07-04T04:59:41Z http://psasir.upm.edu.my/id/eprint/69561/ Rare occurrence of type lll membranoproliferative glomerulonephritis in a patient with hepatitis C in sustained virologic response phase Tan, Yi Jun Then, Ru Fah Lim, Christopher Thiam Seong Hepatitis C virus (HCV) infection is known to cause acute and chronic active hepatitis. In addition, HCV also has systemic disorder involvement that links to various extra-hepatic complications. We report a case of a patient which has been diagnosed to have Hepatitis C Genotype 3A who has been started on antiviral. He achieved end treatment response and sustained virologic response. During routine follow up, he experienced acute kidney injury. Renal biopsy showed type III membranoproliferative glomerulonephritis. His proteinuria improved greatly with the addition of angiotensin converting enzyme inhibitor. This case highlights the possibility of appearance of HCV related glomerulonephritis in patient who has sustained virological response. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/69561/1/2019060311385920_MJMHS_June_2019.pdf Tan, Yi Jun and Then, Ru Fah and Lim, Christopher Thiam Seong (2019) Rare occurrence of type lll membranoproliferative glomerulonephritis in a patient with hepatitis C in sustained virologic response phase. Malaysian Journal of Medicine and Health Sciences, 15 (2). pp. 148-150. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2019060311385920_MJMHS_June_2019.pdf
spellingShingle Tan, Yi Jun
Then, Ru Fah
Lim, Christopher Thiam Seong
Rare occurrence of type lll membranoproliferative glomerulonephritis in a patient with hepatitis C in sustained virologic response phase
title Rare occurrence of type lll membranoproliferative glomerulonephritis in a patient with hepatitis C in sustained virologic response phase
title_full Rare occurrence of type lll membranoproliferative glomerulonephritis in a patient with hepatitis C in sustained virologic response phase
title_fullStr Rare occurrence of type lll membranoproliferative glomerulonephritis in a patient with hepatitis C in sustained virologic response phase
title_full_unstemmed Rare occurrence of type lll membranoproliferative glomerulonephritis in a patient with hepatitis C in sustained virologic response phase
title_short Rare occurrence of type lll membranoproliferative glomerulonephritis in a patient with hepatitis C in sustained virologic response phase
title_sort rare occurrence of type lll membranoproliferative glomerulonephritis in a patient with hepatitis c in sustained virologic response phase
url http://psasir.upm.edu.my/id/eprint/69561/
http://psasir.upm.edu.my/id/eprint/69561/
http://psasir.upm.edu.my/id/eprint/69561/1/2019060311385920_MJMHS_June_2019.pdf