Cytotoxicity of SRJ23 and its derivatives, expression and SRJ23 binding of KRas G12V oncoprotein

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Cytotoxicity of SRJ23 and its derivatives, expression and SRJ23 binding of KRas G12V oncoprotein

Oncogenic KRas signaling is often associated with a poor prognosis of pancreatic cancer. Effort to target oncogenic KRas signaling persists for years but without much success due to its „undruggable‟ property. In recent years, several small-molecule KRas inhibitors such as SRJ23 were developed to in...

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Bibliographic Details
Main Author:	Tan, Michelle Siying
Format:	Thesis
Language:	English
Published:	2017
Subjects:	Pancreatic Neoplasms Oncogene Proteins
Online Access:	http://psasir.upm.edu.my/id/eprint/68578/ http://psasir.upm.edu.my/id/eprint/68578/1/FPSK%28M%29%202018%2013.pdf

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