Quantification of standardised uptake value for ¹⁸F-FDG positron emission tomography in Malaysia

The role of Positron Emission Tomography/Computed Tomography (PET/CT) modalities is becoming more important concomitantly with the increase of oncology cases in Malaysia. Thus, it is the perfect time to perform a study to standardise the PET/CT image quality in Malaysia. This study aimed to compa...

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Main Author: Hanafi, Muhammad Hafiz
Format: Thesis
Language:English
Published: 2017
Subjects:
Online Access:http://psasir.upm.edu.my/id/eprint/68328/
http://psasir.upm.edu.my/id/eprint/68328/1/FPSK%28m%29%202018%208.pdf
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author Hanafi, Muhammad Hafiz
author_facet Hanafi, Muhammad Hafiz
author_sort Hanafi, Muhammad Hafiz
building UPM Institutional Repository
collection Online Access
description The role of Positron Emission Tomography/Computed Tomography (PET/CT) modalities is becoming more important concomitantly with the increase of oncology cases in Malaysia. Thus, it is the perfect time to perform a study to standardise the PET/CT image quality in Malaysia. This study aimed to compare the quantification of image quality of PET/CT with a standardised uptake value (SUV) parameter. In general, this study was carried out with the purpose of identifying the standardisation of quantification of standardised uptake value, SUVcontrolled for 18F-FDG PET between two independent PET modalities at two different institutions. The analysis was done on the SUVcontrolled of technical techniques (PET phantom) as a control standard for the validation of the PET-CT images of selected subjects with Fasting Blood Glucose index as the adjusted index to synchronise the two independent data sets. It was found that the SUVcontrolled was a potential conversion marker to validate the in vivo standardisation techniques for the two independent PET/CT modality systems based on the reference standard of the matched FBS and the in vitro 18F-FDG phantom. This study confirmed that the two independent PET modalities at paired-centre could potentially be standardised on the independent image quality based on the SUVmax quantification as the two independent measured were insignificantly different.
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format Thesis
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institution Universiti Putra Malaysia
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language English
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publishDate 2017
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spelling upm-683282025-06-04T04:56:13Z http://psasir.upm.edu.my/id/eprint/68328/ Quantification of standardised uptake value for ¹⁸F-FDG positron emission tomography in Malaysia Hanafi, Muhammad Hafiz The role of Positron Emission Tomography/Computed Tomography (PET/CT) modalities is becoming more important concomitantly with the increase of oncology cases in Malaysia. Thus, it is the perfect time to perform a study to standardise the PET/CT image quality in Malaysia. This study aimed to compare the quantification of image quality of PET/CT with a standardised uptake value (SUV) parameter. In general, this study was carried out with the purpose of identifying the standardisation of quantification of standardised uptake value, SUVcontrolled for 18F-FDG PET between two independent PET modalities at two different institutions. The analysis was done on the SUVcontrolled of technical techniques (PET phantom) as a control standard for the validation of the PET-CT images of selected subjects with Fasting Blood Glucose index as the adjusted index to synchronise the two independent data sets. It was found that the SUVcontrolled was a potential conversion marker to validate the in vivo standardisation techniques for the two independent PET/CT modality systems based on the reference standard of the matched FBS and the in vitro 18F-FDG phantom. This study confirmed that the two independent PET modalities at paired-centre could potentially be standardised on the independent image quality based on the SUVmax quantification as the two independent measured were insignificantly different. 2017-11 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/68328/1/FPSK%28m%29%202018%208.pdf Hanafi, Muhammad Hafiz (2017) Quantification of standardised uptake value for ¹⁸F-FDG positron emission tomography in Malaysia. Masters thesis, Universiti Putra Malaysia. Positron-Emission Tomography - Malaysia Fluorodeoxyglucose F18
spellingShingle Positron-Emission Tomography - Malaysia
Fluorodeoxyglucose F18
Hanafi, Muhammad Hafiz
Quantification of standardised uptake value for ¹⁸F-FDG positron emission tomography in Malaysia
title Quantification of standardised uptake value for ¹⁸F-FDG positron emission tomography in Malaysia
title_full Quantification of standardised uptake value for ¹⁸F-FDG positron emission tomography in Malaysia
title_fullStr Quantification of standardised uptake value for ¹⁸F-FDG positron emission tomography in Malaysia
title_full_unstemmed Quantification of standardised uptake value for ¹⁸F-FDG positron emission tomography in Malaysia
title_short Quantification of standardised uptake value for ¹⁸F-FDG positron emission tomography in Malaysia
title_sort quantification of standardised uptake value for ¹⁸f-fdg positron emission tomography in malaysia
topic Positron-Emission Tomography - Malaysia
Fluorodeoxyglucose F18
url http://psasir.upm.edu.my/id/eprint/68328/
http://psasir.upm.edu.my/id/eprint/68328/1/FPSK%28m%29%202018%208.pdf