Primary focal segmental glomerulossclerosis and minimal change disease as one spectrum of disease
Minimal Change Disease (MCD) and Focal Segmental Glomerulosclerosis (FSGS) are common causes of nephrotic syndrome. These two conditions are similar in their presentations but differentiated via their histopathological features and responsiveness to corticosteroids. There are ongoing debates whether...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2018
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| Online Access: | http://psasir.upm.edu.my/id/eprint/66135/ http://psasir.upm.edu.my/id/eprint/66135/1/2018092410535113_MJMHS_Oct_2018.pdf |
| _version_ | 1848855481287704576 |
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| author | Then, Ru Fah Tan, Yi Jun Lim, Christopher Thiam Seong |
| author_facet | Then, Ru Fah Tan, Yi Jun Lim, Christopher Thiam Seong |
| author_sort | Then, Ru Fah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Minimal Change Disease (MCD) and Focal Segmental Glomerulosclerosis (FSGS) are common causes of nephrotic syndrome. These two conditions are similar in their presentations but differentiated via their histopathological features and responsiveness to corticosteroids. There are ongoing debates whether MCD and FSGS are at the same spectrum of disease rather than separate entities. FSGS has been postulated to be the severe end of the spectrum of MCD. We have reported a case that has primary FSGS after years of poorly controlled MCD, which supports both conditions are the same spectrum of disease. |
| first_indexed | 2025-11-15T11:26:27Z |
| format | Article |
| id | upm-66135 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:26:27Z |
| publishDate | 2018 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-661352019-02-11T03:55:37Z http://psasir.upm.edu.my/id/eprint/66135/ Primary focal segmental glomerulossclerosis and minimal change disease as one spectrum of disease Then, Ru Fah Tan, Yi Jun Lim, Christopher Thiam Seong Minimal Change Disease (MCD) and Focal Segmental Glomerulosclerosis (FSGS) are common causes of nephrotic syndrome. These two conditions are similar in their presentations but differentiated via their histopathological features and responsiveness to corticosteroids. There are ongoing debates whether MCD and FSGS are at the same spectrum of disease rather than separate entities. FSGS has been postulated to be the severe end of the spectrum of MCD. We have reported a case that has primary FSGS after years of poorly controlled MCD, which supports both conditions are the same spectrum of disease. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/66135/1/2018092410535113_MJMHS_Oct_2018.pdf Then, Ru Fah and Tan, Yi Jun and Lim, Christopher Thiam Seong (2018) Primary focal segmental glomerulossclerosis and minimal change disease as one spectrum of disease. Malaysian Journal of Medicine and Health Sciences, 14 (3). pp. 64-66. ISSN 1675-8544; ESSN: 2636-9346 http://www.medic.upm.edu.my/upload/dokumen/2018092410535113_MJMHS_Oct_2018.pdf |
| spellingShingle | Then, Ru Fah Tan, Yi Jun Lim, Christopher Thiam Seong Primary focal segmental glomerulossclerosis and minimal change disease as one spectrum of disease |
| title | Primary focal segmental glomerulossclerosis and minimal change disease as one spectrum of disease |
| title_full | Primary focal segmental glomerulossclerosis and minimal change disease as one spectrum of disease |
| title_fullStr | Primary focal segmental glomerulossclerosis and minimal change disease as one spectrum of disease |
| title_full_unstemmed | Primary focal segmental glomerulossclerosis and minimal change disease as one spectrum of disease |
| title_short | Primary focal segmental glomerulossclerosis and minimal change disease as one spectrum of disease |
| title_sort | primary focal segmental glomerulossclerosis and minimal change disease as one spectrum of disease |
| url | http://psasir.upm.edu.my/id/eprint/66135/ http://psasir.upm.edu.my/id/eprint/66135/ http://psasir.upm.edu.my/id/eprint/66135/1/2018092410535113_MJMHS_Oct_2018.pdf |