Histological evaluation on burns wound healing treated with nenas (Ananas comosus spp.) and gelam (Melaleuca spp.) honey

The efficacy of topical application of Malaysian honeys on burns wound healing in Sprague-Dawley rats was investigated on the basis of histological changes. A total of 45 Sprague Dawley male rats weighing 200-300 g were used in this study. Deep partial skin thickness burns were inflicted on the dors...

Full description

Bibliographic Details
Main Authors: Mohd Zohdi, Rozaini, Abu Bakar @ Zakaria, Md Zuki, Mohamed Mustapha, Noordin, Yusof, Norimah, Abdullah, Muhammad Nazrul Hakim
Format: Conference or Workshop Item
Language:English
Published: Universiti Putra Malaysia Press 2004
Online Access:http://psasir.upm.edu.my/id/eprint/65120/
http://psasir.upm.edu.my/id/eprint/65120/1/71-37.pdf
_version_ 1848855197483270144
author Mohd Zohdi, Rozaini
Abu Bakar @ Zakaria, Md Zuki
Mohamed Mustapha, Noordin
Yusof, Norimah
Abdullah, Muhammad Nazrul Hakim
author_facet Mohd Zohdi, Rozaini
Abu Bakar @ Zakaria, Md Zuki
Mohamed Mustapha, Noordin
Yusof, Norimah
Abdullah, Muhammad Nazrul Hakim
author_sort Mohd Zohdi, Rozaini
building UPM Institutional Repository
collection Online Access
description The efficacy of topical application of Malaysian honeys on burns wound healing in Sprague-Dawley rats was investigated on the basis of histological changes. A total of 45 Sprague Dawley male rats weighing 200-300 g were used in this study. Deep partial skin thickness burns were inflicted on the dorsal part of each animal. Two types of local honeys (nenas and gelam) were applied twice a day in a quantity of 0.5 ml for each application, while control animals received no treatment. The rats were serially euthanatized at 3, 7, 14, 21 and 28 days post treatment for histological study. Histological examination showed a significant decreased in the number of inflammatory cells and increased vascularity in the honey Gelam-treated wounds as compared to the honey Nenas-treated wounds and control group. This study showed that there was a significant acceleration of the dermal repair in wound healing treated with Gelam honey compared to control and honey Nenas-treated groups.
first_indexed 2025-11-15T11:21:56Z
format Conference or Workshop Item
id upm-65120
institution Universiti Putra Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T11:21:56Z
publishDate 2004
publisher Universiti Putra Malaysia Press
recordtype eprints
repository_type Digital Repository
spelling upm-651202018-09-04T04:04:21Z http://psasir.upm.edu.my/id/eprint/65120/ Histological evaluation on burns wound healing treated with nenas (Ananas comosus spp.) and gelam (Melaleuca spp.) honey Mohd Zohdi, Rozaini Abu Bakar @ Zakaria, Md Zuki Mohamed Mustapha, Noordin Yusof, Norimah Abdullah, Muhammad Nazrul Hakim The efficacy of topical application of Malaysian honeys on burns wound healing in Sprague-Dawley rats was investigated on the basis of histological changes. A total of 45 Sprague Dawley male rats weighing 200-300 g were used in this study. Deep partial skin thickness burns were inflicted on the dorsal part of each animal. Two types of local honeys (nenas and gelam) were applied twice a day in a quantity of 0.5 ml for each application, while control animals received no treatment. The rats were serially euthanatized at 3, 7, 14, 21 and 28 days post treatment for histological study. Histological examination showed a significant decreased in the number of inflammatory cells and increased vascularity in the honey Gelam-treated wounds as compared to the honey Nenas-treated wounds and control group. This study showed that there was a significant acceleration of the dermal repair in wound healing treated with Gelam honey compared to control and honey Nenas-treated groups. Universiti Putra Malaysia Press 2004 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/65120/1/71-37.pdf Mohd Zohdi, Rozaini and Abu Bakar @ Zakaria, Md Zuki and Mohamed Mustapha, Noordin and Yusof, Norimah and Abdullah, Muhammad Nazrul Hakim (2004) Histological evaluation on burns wound healing treated with nenas (Ananas comosus spp.) and gelam (Melaleuca spp.) honey. In: 11th International Conference of the Association of Institutions for Tropical Veterinary Medicine and 16th Veterinary Association Malaysia Congress, 23-27 Aug. 2004, Sunway Pyramid Convention Centre, Petaling Jaya, Malaysia. (pp. 381-383).
spellingShingle Mohd Zohdi, Rozaini
Abu Bakar @ Zakaria, Md Zuki
Mohamed Mustapha, Noordin
Yusof, Norimah
Abdullah, Muhammad Nazrul Hakim
Histological evaluation on burns wound healing treated with nenas (Ananas comosus spp.) and gelam (Melaleuca spp.) honey
title Histological evaluation on burns wound healing treated with nenas (Ananas comosus spp.) and gelam (Melaleuca spp.) honey
title_full Histological evaluation on burns wound healing treated with nenas (Ananas comosus spp.) and gelam (Melaleuca spp.) honey
title_fullStr Histological evaluation on burns wound healing treated with nenas (Ananas comosus spp.) and gelam (Melaleuca spp.) honey
title_full_unstemmed Histological evaluation on burns wound healing treated with nenas (Ananas comosus spp.) and gelam (Melaleuca spp.) honey
title_short Histological evaluation on burns wound healing treated with nenas (Ananas comosus spp.) and gelam (Melaleuca spp.) honey
title_sort histological evaluation on burns wound healing treated with nenas (ananas comosus spp.) and gelam (melaleuca spp.) honey
url http://psasir.upm.edu.my/id/eprint/65120/
http://psasir.upm.edu.my/id/eprint/65120/1/71-37.pdf