Superparamagnetic iron oxide and quantum dots for biomedical applications
Nanomaterials has become insanely popular in biomedical field ranging from contrast agent applications in medical imaging to carriers in gene and drug delivery. Nanomaterials have unique properties that distinguish them from bulk materials in term of size, chemical reactivity, energy absorption and...
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| Format: | Conference or Workshop Item |
| Language: | English |
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2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/64418/ http://psasir.upm.edu.my/id/eprint/64418/1/MST%20poster%20111117%2017.pdf |
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| author | Zainon, Nur Khalida Rahayu Che Abdullah, Che Azurahanim Abdul Rahman, Mohd Basyaruddin Masarudin, Mas Jaffri |
| author_facet | Zainon, Nur Khalida Rahayu Che Abdullah, Che Azurahanim Abdul Rahman, Mohd Basyaruddin Masarudin, Mas Jaffri |
| author_sort | Zainon, Nur Khalida Rahayu |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Nanomaterials has become insanely popular in biomedical field ranging from contrast agent applications in medical imaging to carriers in gene and drug delivery. Nanomaterials have unique properties that distinguish them from bulk materials in term of size, chemical reactivity, energy absorption and biological mobility. Magnetic nanoparticles (Fe3O4) posses superparamagnetic properties, which is widely known for its application as a contrast agent in MRI and as nanocarrier in targeted drug delivery. Semiconductor quantum dots (CdSe-ZnS) have strong fluorescent properties and the wavelength emitted depend sensitively on particle size. It have extensive applications in organic light emitting diode (OLED), sensor, and fluorescent biological labels. Current work are focusing on synthesis and characterization of biocompatible magnetic nanoparticles and fluorescence quantum dots, as well as toxicity of the nanomaterials for the biomedical application and gene therapy specifically. Magnetic nanoparticles (Fe3O4) and semiconductor quantum dots (CdSe-ZnS) are both synthesized using co-precipitation method and microwave irradiation technique respectively. The synthesized nanoparticles were characterized with X-Ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Transmission Electron Microscopy (TEM), and Vibrating Sample Magnetometry (VSM). The toxicity of both type of nanoparticles were tested on 2 different cell line; A549 human lung carcinoma and MRC5 human lung fibroblast using MTT assay. This research explores the potentials of these two types of nanomaterials in biomedical applications. |
| first_indexed | 2025-11-15T11:18:44Z |
| format | Conference or Workshop Item |
| id | upm-64418 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:18:44Z |
| publishDate | 2017 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-644182018-07-05T09:28:30Z http://psasir.upm.edu.my/id/eprint/64418/ Superparamagnetic iron oxide and quantum dots for biomedical applications Zainon, Nur Khalida Rahayu Che Abdullah, Che Azurahanim Abdul Rahman, Mohd Basyaruddin Masarudin, Mas Jaffri Nanomaterials has become insanely popular in biomedical field ranging from contrast agent applications in medical imaging to carriers in gene and drug delivery. Nanomaterials have unique properties that distinguish them from bulk materials in term of size, chemical reactivity, energy absorption and biological mobility. Magnetic nanoparticles (Fe3O4) posses superparamagnetic properties, which is widely known for its application as a contrast agent in MRI and as nanocarrier in targeted drug delivery. Semiconductor quantum dots (CdSe-ZnS) have strong fluorescent properties and the wavelength emitted depend sensitively on particle size. It have extensive applications in organic light emitting diode (OLED), sensor, and fluorescent biological labels. Current work are focusing on synthesis and characterization of biocompatible magnetic nanoparticles and fluorescence quantum dots, as well as toxicity of the nanomaterials for the biomedical application and gene therapy specifically. Magnetic nanoparticles (Fe3O4) and semiconductor quantum dots (CdSe-ZnS) are both synthesized using co-precipitation method and microwave irradiation technique respectively. The synthesized nanoparticles were characterized with X-Ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Transmission Electron Microscopy (TEM), and Vibrating Sample Magnetometry (VSM). The toxicity of both type of nanoparticles were tested on 2 different cell line; A549 human lung carcinoma and MRC5 human lung fibroblast using MTT assay. This research explores the potentials of these two types of nanomaterials in biomedical applications. 2017 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/64418/1/MST%20poster%20111117%2017.pdf Zainon, Nur Khalida Rahayu and Che Abdullah, Che Azurahanim and Abdul Rahman, Mohd Basyaruddin and Masarudin, Mas Jaffri (2017) Superparamagnetic iron oxide and quantum dots for biomedical applications. In: 5th International Symposium on Applied Engineering and Sciences (SAES2017), 14-15 Nov. 2017, Universiti Putra Malaysia. (p. 17). |
| spellingShingle | Zainon, Nur Khalida Rahayu Che Abdullah, Che Azurahanim Abdul Rahman, Mohd Basyaruddin Masarudin, Mas Jaffri Superparamagnetic iron oxide and quantum dots for biomedical applications |
| title | Superparamagnetic iron oxide and quantum dots for biomedical applications |
| title_full | Superparamagnetic iron oxide and quantum dots for biomedical applications |
| title_fullStr | Superparamagnetic iron oxide and quantum dots for biomedical applications |
| title_full_unstemmed | Superparamagnetic iron oxide and quantum dots for biomedical applications |
| title_short | Superparamagnetic iron oxide and quantum dots for biomedical applications |
| title_sort | superparamagnetic iron oxide and quantum dots for biomedical applications |
| url | http://psasir.upm.edu.my/id/eprint/64418/ http://psasir.upm.edu.my/id/eprint/64418/1/MST%20poster%20111117%2017.pdf |