Carboxymethyl sago starch based hydrogel for drug delivery application
Chemically modified sago starch into carboxymethyl sago starch (CMSS) was done by using carboxymethylation reaction. The reaction times are varied to determine the optimum degree of substitution (DS) and reaction efficiency (RE). CMSS prepared via carboxymethylation for 3 hours show the highest DS a...
| Main Authors: | , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/64411/ http://psasir.upm.edu.my/id/eprint/64411/1/MST%20poster%20111117%206.pdf |
| _version_ | 1848854994563891200 |
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| author | Nordin, Nurul Aida Abdul Rahman, Norizah |
| author_facet | Nordin, Nurul Aida Abdul Rahman, Norizah |
| author_sort | Nordin, Nurul Aida |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Chemically modified sago starch into carboxymethyl sago starch (CMSS) was done by using carboxymethylation reaction. The reaction times are varied to determine the optimum degree of substitution (DS) and reaction efficiency (RE). CMSS prepared via carboxymethylation for 3 hours show the highest DS and RE. The CMSS hydrogel was prepared using citric acid as cross-linker. The effects of the preparation condition of CMSS hydrogel such as the percentage of citric acid (w/w), cross-linking periods and cross-linking temperature on the gel fraction were investigated. The swelling study was carried out in distilled water, acidic, neutral and alkaline medium. The release behaviour of methylene blue (MB) as the drug model demonstrates that CMSS hydrogel has potential to be use in drug delivery applications. |
| first_indexed | 2025-11-15T11:18:43Z |
| format | Conference or Workshop Item |
| id | upm-64411 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:18:43Z |
| publishDate | 2017 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-644112018-07-05T09:29:29Z http://psasir.upm.edu.my/id/eprint/64411/ Carboxymethyl sago starch based hydrogel for drug delivery application Nordin, Nurul Aida Abdul Rahman, Norizah Chemically modified sago starch into carboxymethyl sago starch (CMSS) was done by using carboxymethylation reaction. The reaction times are varied to determine the optimum degree of substitution (DS) and reaction efficiency (RE). CMSS prepared via carboxymethylation for 3 hours show the highest DS and RE. The CMSS hydrogel was prepared using citric acid as cross-linker. The effects of the preparation condition of CMSS hydrogel such as the percentage of citric acid (w/w), cross-linking periods and cross-linking temperature on the gel fraction were investigated. The swelling study was carried out in distilled water, acidic, neutral and alkaline medium. The release behaviour of methylene blue (MB) as the drug model demonstrates that CMSS hydrogel has potential to be use in drug delivery applications. 2017 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/64411/1/MST%20poster%20111117%206.pdf Nordin, Nurul Aida and Abdul Rahman, Norizah (2017) Carboxymethyl sago starch based hydrogel for drug delivery application. In: 5th International Symposium on Applied Engineering and Sciences (SAES2017), 14-15 Nov. 2017, Universiti Putra Malaysia. (p. 6). |
| spellingShingle | Nordin, Nurul Aida Abdul Rahman, Norizah Carboxymethyl sago starch based hydrogel for drug delivery application |
| title | Carboxymethyl sago starch based hydrogel for drug delivery application |
| title_full | Carboxymethyl sago starch based hydrogel for drug delivery application |
| title_fullStr | Carboxymethyl sago starch based hydrogel for drug delivery application |
| title_full_unstemmed | Carboxymethyl sago starch based hydrogel for drug delivery application |
| title_short | Carboxymethyl sago starch based hydrogel for drug delivery application |
| title_sort | carboxymethyl sago starch based hydrogel for drug delivery application |
| url | http://psasir.upm.edu.my/id/eprint/64411/ http://psasir.upm.edu.my/id/eprint/64411/1/MST%20poster%20111117%206.pdf |