Identification of Protein Kinase Inhibitory Activities Fromstreptomyces Strain H7372 for Potential Use As Anti-Canceragent
Aberrations in the phospbatidylinositol3-kinase (PI3K)IAkt pathway have been found in a wide spectrum of human cancers. Activation of Akt and inactivation of the downstream substrates such as GSK-3P, BAD and Forkhead family (FKHR) proteins are relevant to promote cell survival, proliferation and...
| Main Author: | Hassan, Masriana |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2007
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/6438/ http://psasir.upm.edu.my/id/eprint/6438/1/FPSK%28M%29_2007_18.pdf |
Similar Items
Anti-proliferative and anti-invasive properties of a purified fraction from Streptomyces sp. H7372.
by: Yip, Wai Kien, et al.
Published: (2010)
by: Yip, Wai Kien, et al.
Published: (2010)
Three new amides from Streptomyces sp. H7372
by: Cheenpracha, Sarot, et al.
Published: (2011)
by: Cheenpracha, Sarot, et al.
Published: (2011)
Isolation of a potential anticancer agent with protein phosphatase inhibitory activity from soil-derived Penicillium sp. strain H9318
by: Ooi, S. C., et al.
Published: (2016)
by: Ooi, S. C., et al.
Published: (2016)
Identification of anti-proliferative kinase inhibitors as potential therapeutic agents to treat canine osteosarcoma
by: Mauchle, Ulrike, et al.
Published: (2015)
by: Mauchle, Ulrike, et al.
Published: (2015)
Enzymology method to determine the anti-inflammatory potentials: hyaluronidase inhibitory activity bioassay
by: Abdullah, Nor Hayati, et al.
Published: (2015)
by: Abdullah, Nor Hayati, et al.
Published: (2015)
Phosphorylation And Regulation
Of Human Choline Kinase Beta
By Protein Kinase A
by: Chang , Ching Ching
Published: (2015)
by: Chang , Ching Ching
Published: (2015)
Phosphorylation And Regulation
Of Human Choline Kinase Beta
By Protein Kinase A
by: Chang , Ching Ching
Published: (2015)
by: Chang , Ching Ching
Published: (2015)
Anti–elastase, anti–tyrosinase and matrix metalloproteinase–1 inhibitory activity of earthworm extracts as potential new anti–aging agent
by: Azmi, Nurhazirah, et al.
Published: (2014)
by: Azmi, Nurhazirah, et al.
Published: (2014)
Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase
by: Mor, I., et al.
Published: (2012)
by: Mor, I., et al.
Published: (2012)
Analysis of phosphorylation sites of protein kinases in Cryptosporidium
by: Barudin, Mohd Aiman, et al.
Published: (2018)
by: Barudin, Mohd Aiman, et al.
Published: (2018)
Differential time course of glycogen synthase kinase-3 inhibition in experimental autoimmune encephalomyelitis
by: Al-Zaidi, Ahmed Salam, et al.
Published: (2021)
by: Al-Zaidi, Ahmed Salam, et al.
Published: (2021)
Extraction And Identification Of Elastase Inhibitory Peptides From Digested Ovalbumin As Skin Anti-Aging
Therapeutics Agent
by: Chok, Wen Xin
Published: (2020)
by: Chok, Wen Xin
Published: (2020)
Effects of protein kinase a phosphorylation on
the biochemical properties and subcellular
location of human choline kinase beta
by: Cun, See Too Wei
Published: (2016)
by: Cun, See Too Wei
Published: (2016)
Characterisation of inhibitory activity of metabolites produced by six strains of Lactobacillus plantarum.
by: Foo, Hooi Ling, et al.
by: Foo, Hooi Ling, et al.
Molecular dynamics simulations of DARPins as potential inhibitors against cancer associated protein kinases / Vertika Gautam
by: Vertika , Gautam
Published: (2021)
by: Vertika , Gautam
Published: (2021)
Dissecting the role of histidine kinase and Hog1 mitogen-activated protein kinase signalling in stress tolerance and pathogenicity of Parastagonospora nodorum on wheat.
by: John, E., et al.
Published: (2016)
by: John, E., et al.
Published: (2016)
Bioactive compounds, antioxidant, xanthine oxidase inhibitory, tyrosinase inhibitory and anti-inflammatory activities of selected agro-industrial by-products
by: Oskoueian, Ehsan, et al.
Published: (2011)
by: Oskoueian, Ehsan, et al.
Published: (2011)
Akt/protein kinase B in skeletal muscle physiology and pathology
by: Wu, M., et al.
Published: (2011)
by: Wu, M., et al.
Published: (2011)
Clinicopathological and prognostic significance of mitogen-activated protein kinases (MAPK) in breast cancers
by: Ahmad, Dena Akram Jerjees, et al.
Published: (2016)
by: Ahmad, Dena Akram Jerjees, et al.
Published: (2016)
LIM kinase function and renal growth: potential role for LIM kinases in fetal programming of kidney development
by: Sparrow, Alexander J., et al.
Published: (2017)
by: Sparrow, Alexander J., et al.
Published: (2017)
Mechanisms of disordered neurodegenerative function: concepts and facts about the different roles of the protein kinase RNA-like endoplasmic reticulum kinase (PERK)
by: Taalab, Yasmeen M., et al.
Published: (2018)
by: Taalab, Yasmeen M., et al.
Published: (2018)
Potentially bioactive metabolites from pineapple waste extracts and their antioxidant and α-glucosidase inhibitory activities by 1H NMR
by: Azizan, Awanis, et al.
Published: (2020)
by: Azizan, Awanis, et al.
Published: (2020)
Cyclin dependent Kinases as potential therapeutic targets for atherosclerosis
by: Rostam, Muhamad Ashraf, et al.
Published: (2015)
by: Rostam, Muhamad Ashraf, et al.
Published: (2015)
Growth inhibitory potential and anti-metastatic effect of camel urine on 4T1 cell line in vitro and in vivo
by: Romli, Muhammad Firdaus
Published: (2016)
by: Romli, Muhammad Firdaus
Published: (2016)
Inhibitory property of metabolite combinations produced from Lactobacillus plantarum strains
by: Choe, Di Wei, et al.
Published: (2013)
by: Choe, Di Wei, et al.
Published: (2013)
Investigating the role of calcium/calmodulin-dependent protein kinases in Stagonospora nodorum
by: Solomon, P., et al.
Published: (2006)
by: Solomon, P., et al.
Published: (2006)
The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets
by: Canobbio, I., et al.
Published: (2015)
by: Canobbio, I., et al.
Published: (2015)
Inhibitory activity and organic acid concentrations of metabolite combinations produced by various strains of Lactobacillus plantarum
by: Thu, Tran Van, et al.
Published: (2011)
by: Thu, Tran Van, et al.
Published: (2011)
Inhibitory activity of metabolites produced by strains of Lactobacillus plantarum isolated from Malaysian fermented food.
by: Nguyen, Tien Thanh, et al.
Published: (2010)
by: Nguyen, Tien Thanh, et al.
Published: (2010)
Inhibitory activity of postbiotic produced by strains of Lactobacillus plantarum using reconstituted media supplemented with inulin
by: Kareem, Karwan Yassen, et al.
Published: (2014)
by: Kareem, Karwan Yassen, et al.
Published: (2014)
Angiotensin-I converting enzyme (ACE) inhibitory and anti-hypertensive effect of protein hydrolysate from Actinopyga Iecanora (sea cucumber) in rats
by: Vishkaei, Mahdokht Sadegh, et al.
Published: (2016)
by: Vishkaei, Mahdokht Sadegh, et al.
Published: (2016)
Phenolic composition, antioxidant, anti-wrinkles and tyrosinase inhibitory activities of cocoa pod extract
by: Abdul Karim, Azila, et al.
Published: (2014)
by: Abdul Karim, Azila, et al.
Published: (2014)
Protein kinase G-induced activation of KATP channels reduces contractility of human prostate tissue
by: Haynes, J., et al.
Published: (2006)
by: Haynes, J., et al.
Published: (2006)
Targeted RNAi of the mitogen-activated protein kinase pathway
genes in acute myeloid leukemia cells
by: Mohd Hafiz, M.R., et al.
Published: (2013)
by: Mohd Hafiz, M.R., et al.
Published: (2013)
Alpha-amylase inhibitory activity of inhibitor proteins in
different types of commercial rice
by: Ramli, Nur Syazila, et al.
Published: (2018)
by: Ramli, Nur Syazila, et al.
Published: (2018)
Protein Kinase C-Delta C2 Domain Interactions in Breast Cancer
by: Khader, Rasha
Published: (2023)
by: Khader, Rasha
Published: (2023)
Chronic activation of AMP-activated protein kinase prevents 20-hydroxyeicosatetraenoic acid-induced endothelial dysfunction
by: Ward, Natalie, et al.
Published: (2011)
by: Ward, Natalie, et al.
Published: (2011)
Identification of potential plasma protein markers for gestational diabetes mellitus
by: Sangaran, Puspha Gandi
Published: (2012)
by: Sangaran, Puspha Gandi
Published: (2012)
In silico homology modelling and identification of Tousled-like kinase 1 inhibitors for glioblastoma therapy via high throughput virtual screening protein-ligand docking
by: Kamariah Ibrahim,, et al.
Published: (2018)
by: Kamariah Ibrahim,, et al.
Published: (2018)
Mitogen-activated protein/extracellular signal-regulated kinase kinase 1act/tubulin interaction is an important determinant of mitotic stability in cultured HT1080 human fibrosarcoma cells.
by: Cao, Jia-ning, et al.
Published: (2010)
by: Cao, Jia-ning, et al.
Published: (2010)
Similar Items
-
Anti-proliferative and anti-invasive properties of a purified fraction from Streptomyces sp. H7372.
by: Yip, Wai Kien, et al.
Published: (2010) -
Three new amides from Streptomyces sp. H7372
by: Cheenpracha, Sarot, et al.
Published: (2011) -
Isolation of a potential anticancer agent with protein phosphatase inhibitory activity from soil-derived Penicillium sp. strain H9318
by: Ooi, S. C., et al.
Published: (2016) -
Identification of anti-proliferative kinase inhibitors as potential therapeutic agents to treat canine osteosarcoma
by: Mauchle, Ulrike, et al.
Published: (2015) -
Enzymology method to determine the anti-inflammatory potentials: hyaluronidase inhibitory activity bioassay
by: Abdullah, Nor Hayati, et al.
Published: (2015)