Antimicrobial properties and brine shrimp toxicity of anti-cancer herbs : Pereskia bleo, Pereskia grandifolia and Strobilanthes crispus
Pereskia bleo, Pereskia grandifolia and Strobilanthes crispus are widely recognized as anti-cancer herbs among local community. The antimicrobial properties and toxicity of these herbs were analyzed. Aqueous extraction using both blending and decoction methods were used to obtain the herbal crude ex...
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| Format: | Conference or Workshop Item |
| Language: | English |
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Sarawak Biodiversity Centre
2008
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| Online Access: | http://psasir.upm.edu.my/id/eprint/64271/ http://psasir.upm.edu.my/id/eprint/64271/1/PROCEEDING_100719-9.pdf |
| _version_ | 1848854954941349888 |
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| author | Siew, Keng Yew Wong, Sing King |
| author_facet | Siew, Keng Yew Wong, Sing King |
| author_sort | Siew, Keng Yew |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Pereskia bleo, Pereskia grandifolia and Strobilanthes crispus are widely recognized as anti-cancer herbs among local community. The antimicrobial properties and toxicity of these herbs were analyzed. Aqueous extraction using both blending and decoction methods were used to obtain the herbal crude extracts. Antibacterial susceptible testing of the extracts was done using disc diffusion and minimum inhibition concentration (MIC) techniques. Toxicity test against brine shrimps was performed to determine the lethal dose (LD50) of those plant extracts. All the crude extracts of P. bleo, P. grandifolia and S. crispus did not show any antibacterial activities against Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Pseudomonas aeruginosa at amount up to 1000 ppm for MIC and 200 μg in disc diffusion. P. bleo and S. crispus showed LC50 values beyond 1000 ppm. The LC50 value of blended and decocted extracts of P. grandifolia was 13.34 μg/ml and 66.07 μg/ml respectively. |
| first_indexed | 2025-11-15T11:18:05Z |
| format | Conference or Workshop Item |
| id | upm-64271 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:18:05Z |
| publishDate | 2008 |
| publisher | Sarawak Biodiversity Centre |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-642712018-07-04T02:31:45Z http://psasir.upm.edu.my/id/eprint/64271/ Antimicrobial properties and brine shrimp toxicity of anti-cancer herbs : Pereskia bleo, Pereskia grandifolia and Strobilanthes crispus Siew, Keng Yew Wong, Sing King Pereskia bleo, Pereskia grandifolia and Strobilanthes crispus are widely recognized as anti-cancer herbs among local community. The antimicrobial properties and toxicity of these herbs were analyzed. Aqueous extraction using both blending and decoction methods were used to obtain the herbal crude extracts. Antibacterial susceptible testing of the extracts was done using disc diffusion and minimum inhibition concentration (MIC) techniques. Toxicity test against brine shrimps was performed to determine the lethal dose (LD50) of those plant extracts. All the crude extracts of P. bleo, P. grandifolia and S. crispus did not show any antibacterial activities against Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Pseudomonas aeruginosa at amount up to 1000 ppm for MIC and 200 μg in disc diffusion. P. bleo and S. crispus showed LC50 values beyond 1000 ppm. The LC50 value of blended and decocted extracts of P. grandifolia was 13.34 μg/ml and 66.07 μg/ml respectively. Sarawak Biodiversity Centre 2008 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/64271/1/PROCEEDING_100719-9.pdf Siew, Keng Yew and Wong, Sing King (2008) Antimicrobial properties and brine shrimp toxicity of anti-cancer herbs : Pereskia bleo, Pereskia grandifolia and Strobilanthes crispus. In: Biodiversity and Biotechnology Symposium 2008, 19-21 Nov. 2008, Kuching, Sarawak, Malaysia. (pp. 268-271). |
| spellingShingle | Siew, Keng Yew Wong, Sing King Antimicrobial properties and brine shrimp toxicity of anti-cancer herbs : Pereskia bleo, Pereskia grandifolia and Strobilanthes crispus |
| title | Antimicrobial properties and brine shrimp toxicity of anti-cancer herbs : Pereskia bleo, Pereskia grandifolia and Strobilanthes crispus |
| title_full | Antimicrobial properties and brine shrimp toxicity of anti-cancer herbs : Pereskia bleo, Pereskia grandifolia and Strobilanthes crispus |
| title_fullStr | Antimicrobial properties and brine shrimp toxicity of anti-cancer herbs : Pereskia bleo, Pereskia grandifolia and Strobilanthes crispus |
| title_full_unstemmed | Antimicrobial properties and brine shrimp toxicity of anti-cancer herbs : Pereskia bleo, Pereskia grandifolia and Strobilanthes crispus |
| title_short | Antimicrobial properties and brine shrimp toxicity of anti-cancer herbs : Pereskia bleo, Pereskia grandifolia and Strobilanthes crispus |
| title_sort | antimicrobial properties and brine shrimp toxicity of anti-cancer herbs : pereskia bleo, pereskia grandifolia and strobilanthes crispus |
| url | http://psasir.upm.edu.my/id/eprint/64271/ http://psasir.upm.edu.my/id/eprint/64271/1/PROCEEDING_100719-9.pdf |