Numerical modelling of blood cells distribution in flow through cerebral artery aneurysm

Recent aneurysm studies have focused on the correlation between different parameters and rupture risk; however, there have been conflicting findings. Computational fluid dynamics (CFD) allows for better visualization but idealized aneurysm models may neglect important variables such as aneurysm shap...

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Main Authors: Arshad, Syazatul Aniza, Sabir, Osama, Huang, Joanne, Ly, Kevin, Nguyen, Angela, Tuan Ya, Tuan Mohammad Yusoff Shah, Muda, Ahmad Sobri, Mohammad Razi, Adli Azam, Shuib, Anis Suhaila
Format: Article
Language:English
Published: Penerbit UTM Press 2018
Online Access:http://psasir.upm.edu.my/id/eprint/64088/
http://psasir.upm.edu.my/id/eprint/64088/1/Numerical%20modelling%20of%20blood%20cells%20distribution%20in%20flow%20through%20cerebral%20artery%20aneurysm.pdf
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author Arshad, Syazatul Aniza
Sabir, Osama
Huang, Joanne
Ly, Kevin
Nguyen, Angela
Tuan Ya, Tuan Mohammad Yusoff Shah
Muda, Ahmad Sobri
Mohammad Razi, Adli Azam
Shuib, Anis Suhaila
author_facet Arshad, Syazatul Aniza
Sabir, Osama
Huang, Joanne
Ly, Kevin
Nguyen, Angela
Tuan Ya, Tuan Mohammad Yusoff Shah
Muda, Ahmad Sobri
Mohammad Razi, Adli Azam
Shuib, Anis Suhaila
author_sort Arshad, Syazatul Aniza
building UPM Institutional Repository
collection Online Access
description Recent aneurysm studies have focused on the correlation between different parameters and rupture risk; however, there have been conflicting findings. Computational fluid dynamics (CFD) allows for better visualization but idealized aneurysm models may neglect important variables such as aneurysm shape and blood flow conditions. In this paper, one case of an aneurysm was studied with CFD using a non-Newtonian Power Law Model to investigate the correlation between wall shear stress and blood cells distribution. Results show that velocity of blood flow decreased as it entered the aneurysm and the neck of the aneurysm experienced a greater magnitude of wall shear stress than the remainder of the cerebral artery. Besides, the blood cells generally begin at low velocities and increase after the first curve of the artery. Findings and further studies with larger cases of patients will improve treatment and prevention of aneurysm ruptures.
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institution Universiti Putra Malaysia
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publisher Penerbit UTM Press
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spelling upm-640882018-06-11T08:17:50Z http://psasir.upm.edu.my/id/eprint/64088/ Numerical modelling of blood cells distribution in flow through cerebral artery aneurysm Arshad, Syazatul Aniza Sabir, Osama Huang, Joanne Ly, Kevin Nguyen, Angela Tuan Ya, Tuan Mohammad Yusoff Shah Muda, Ahmad Sobri Mohammad Razi, Adli Azam Shuib, Anis Suhaila Recent aneurysm studies have focused on the correlation between different parameters and rupture risk; however, there have been conflicting findings. Computational fluid dynamics (CFD) allows for better visualization but idealized aneurysm models may neglect important variables such as aneurysm shape and blood flow conditions. In this paper, one case of an aneurysm was studied with CFD using a non-Newtonian Power Law Model to investigate the correlation between wall shear stress and blood cells distribution. Results show that velocity of blood flow decreased as it entered the aneurysm and the neck of the aneurysm experienced a greater magnitude of wall shear stress than the remainder of the cerebral artery. Besides, the blood cells generally begin at low velocities and increase after the first curve of the artery. Findings and further studies with larger cases of patients will improve treatment and prevention of aneurysm ruptures. Penerbit UTM Press 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/64088/1/Numerical%20modelling%20of%20blood%20cells%20distribution%20in%20flow%20through%20cerebral%20artery%20aneurysm.pdf Arshad, Syazatul Aniza and Sabir, Osama and Huang, Joanne and Ly, Kevin and Nguyen, Angela and Tuan Ya, Tuan Mohammad Yusoff Shah and Muda, Ahmad Sobri and Mohammad Razi, Adli Azam and Shuib, Anis Suhaila (2018) Numerical modelling of blood cells distribution in flow through cerebral artery aneurysm. Malaysian Journal of Fundamental and Applied Sciences, 14 (1). pp. 127-132. ISSN 2289-5981; ESSN: 2289-599X https://mjfas.utm.my/index.php/mjfas/article/view/915 10.11113/mjfas.v14n1.915
spellingShingle Arshad, Syazatul Aniza
Sabir, Osama
Huang, Joanne
Ly, Kevin
Nguyen, Angela
Tuan Ya, Tuan Mohammad Yusoff Shah
Muda, Ahmad Sobri
Mohammad Razi, Adli Azam
Shuib, Anis Suhaila
Numerical modelling of blood cells distribution in flow through cerebral artery aneurysm
title Numerical modelling of blood cells distribution in flow through cerebral artery aneurysm
title_full Numerical modelling of blood cells distribution in flow through cerebral artery aneurysm
title_fullStr Numerical modelling of blood cells distribution in flow through cerebral artery aneurysm
title_full_unstemmed Numerical modelling of blood cells distribution in flow through cerebral artery aneurysm
title_short Numerical modelling of blood cells distribution in flow through cerebral artery aneurysm
title_sort numerical modelling of blood cells distribution in flow through cerebral artery aneurysm
url http://psasir.upm.edu.my/id/eprint/64088/
http://psasir.upm.edu.my/id/eprint/64088/
http://psasir.upm.edu.my/id/eprint/64088/
http://psasir.upm.edu.my/id/eprint/64088/1/Numerical%20modelling%20of%20blood%20cells%20distribution%20in%20flow%20through%20cerebral%20artery%20aneurysm.pdf