Zn2+ cross-linked sodium alginate-g-allylamine-mannose polymeric carrier of rifampicin for macrophage targeting tuberculosis nanotherapy
Our aim was to evaluate the capacity of polymeric nanoparticles (PNPs) to selectively deliver an antituberculosis drug (rifampicin; RF) to alveolar macrophages. Anionic biodegradable copolymer sodium alginate-g-allylamine-mannose (SA-g-AA-M) was synthesized by atom transfer free radical polymerizati...
| Main Authors: | Praphakar, Rajendran Amarnath, Munusamy, Murugan A., Alarfaj, Abdullah A., Kumar, Suresh, Rajan, Mariappan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Royal Society of Chemistry
2017
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/63743/ http://psasir.upm.edu.my/id/eprint/63743/1/Zn2%2B%20cross-linked%20sodium%20alginate-g-allylamine-mannose%20polymeric%20carrier%20of%20rifampicin%20for%20macrophage%20targeting%20tuberculosis%20nanotherapy.pdf |
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