Zebrafish phenotypic screen identifies novel Notch antagonists
Zebrafish represents a powerful in vivo model for phenotype-based drug discovery to identify clinically relevant small molecules. By utilizing this model, we evaluated natural product derived compounds that could potentially modulate Notch signaling that is important in both zebrafish embryogenesis...
| Main Authors: | Velaithan, Vithya, Okuda, Kazuhide Shaun, Mei, Fong Ng, Samat, Norazwana, Sze, Wei Leong, Faudzi, Siti Munirah Mohd, Abas, Faridah, Shaari, Khozirah, Sok, Ching Cheong, Pei, Jean Tan, Patel, Vyomesh |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2017
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/63740/ http://psasir.upm.edu.my/id/eprint/63740/1/Zebrafish%20phenotypic%20screen%20identifies%20novel%20Notch%20antagonists.pdf |
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