Therapeutic uses of epicatechin in diabetes and cancer

Epicatechin is a natural flavonoid found in green tea. It has been reported to possess an immense antioxidant effect which contributes to its therapeutic effect against a handful of ailments. In this review, we discuss its therapeutic role in the management of two of the most important human disease...

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Main Authors: Abdulkhaleq, Layth Abdulmajeed, Assi, Mohammed Abdulrazzaq, Noor, Mohd Hezmee Mohd, Abdullah, Rasedee, Saad, Mohd Zamri, Taufiq-Yap, Yun Hin
Format: Article
Language:English
Published: Veterinary World 2017
Online Access:http://psasir.upm.edu.my/id/eprint/63559/
http://psasir.upm.edu.my/id/eprint/63559/1/Therapeutic%20uses%20of%20epicatechin%20in%20diabetes%20and%20cancer.pdf
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author Abdulkhaleq, Layth Abdulmajeed
Assi, Mohammed Abdulrazzaq
Noor, Mohd Hezmee Mohd
Abdullah, Rasedee
Saad, Mohd Zamri
Taufiq-Yap, Yun Hin
author_facet Abdulkhaleq, Layth Abdulmajeed
Assi, Mohammed Abdulrazzaq
Noor, Mohd Hezmee Mohd
Abdullah, Rasedee
Saad, Mohd Zamri
Taufiq-Yap, Yun Hin
author_sort Abdulkhaleq, Layth Abdulmajeed
building UPM Institutional Repository
collection Online Access
description Epicatechin is a natural flavonoid found in green tea. It has been reported to possess an immense antioxidant effect which contributes to its therapeutic effect against a handful of ailments. In this review, we discuss its therapeutic role in the management of two of the most important human diseases; diabetes and cancer. The consumption of epicatechin has been shown to reduce blood glucose levels in diabetic patients, while is anticancer effect was attributed to its antioxidant properties, antiangiogenic and direct cytotoxicity to cancer cells. Although the exact mechanism of action of epicatechin is still being explored, there is no doubt that it is a promising candidate as an alternative. The significance of this review is to highlight the importance of the usage of natural products (in this case, epicatechin) as an alternative for the treatment of two potentially fatal diseases which is diabetes and cancer. The aim of this review is to educate the scientific community on the role of epicatechin in ameliorating the effects of diabetes and cancers on human while understanding the potential mechanisms of these aforementioned effects.
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spelling upm-635592018-11-05T03:24:22Z http://psasir.upm.edu.my/id/eprint/63559/ Therapeutic uses of epicatechin in diabetes and cancer Abdulkhaleq, Layth Abdulmajeed Assi, Mohammed Abdulrazzaq Noor, Mohd Hezmee Mohd Abdullah, Rasedee Saad, Mohd Zamri Taufiq-Yap, Yun Hin Epicatechin is a natural flavonoid found in green tea. It has been reported to possess an immense antioxidant effect which contributes to its therapeutic effect against a handful of ailments. In this review, we discuss its therapeutic role in the management of two of the most important human diseases; diabetes and cancer. The consumption of epicatechin has been shown to reduce blood glucose levels in diabetic patients, while is anticancer effect was attributed to its antioxidant properties, antiangiogenic and direct cytotoxicity to cancer cells. Although the exact mechanism of action of epicatechin is still being explored, there is no doubt that it is a promising candidate as an alternative. The significance of this review is to highlight the importance of the usage of natural products (in this case, epicatechin) as an alternative for the treatment of two potentially fatal diseases which is diabetes and cancer. The aim of this review is to educate the scientific community on the role of epicatechin in ameliorating the effects of diabetes and cancers on human while understanding the potential mechanisms of these aforementioned effects. Veterinary World 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/63559/1/Therapeutic%20uses%20of%20epicatechin%20in%20diabetes%20and%20cancer.pdf Abdulkhaleq, Layth Abdulmajeed and Assi, Mohammed Abdulrazzaq and Noor, Mohd Hezmee Mohd and Abdullah, Rasedee and Saad, Mohd Zamri and Taufiq-Yap, Yun Hin (2017) Therapeutic uses of epicatechin in diabetes and cancer. Veterinary World, 10 (8). 869 - 872. ISSN 0972-8988; ESSN: 2231-0916 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591471/pdf/VetWorld-10-869.pdf 10.14202/vetworld.2017.869-872
spellingShingle Abdulkhaleq, Layth Abdulmajeed
Assi, Mohammed Abdulrazzaq
Noor, Mohd Hezmee Mohd
Abdullah, Rasedee
Saad, Mohd Zamri
Taufiq-Yap, Yun Hin
Therapeutic uses of epicatechin in diabetes and cancer
title Therapeutic uses of epicatechin in diabetes and cancer
title_full Therapeutic uses of epicatechin in diabetes and cancer
title_fullStr Therapeutic uses of epicatechin in diabetes and cancer
title_full_unstemmed Therapeutic uses of epicatechin in diabetes and cancer
title_short Therapeutic uses of epicatechin in diabetes and cancer
title_sort therapeutic uses of epicatechin in diabetes and cancer
url http://psasir.upm.edu.my/id/eprint/63559/
http://psasir.upm.edu.my/id/eprint/63559/
http://psasir.upm.edu.my/id/eprint/63559/
http://psasir.upm.edu.my/id/eprint/63559/1/Therapeutic%20uses%20of%20epicatechin%20in%20diabetes%20and%20cancer.pdf