Systematic review on the accuracy of positron emission tomography/computed tomography and positron emission tomography/magnetic resonance imaging in the management of ovarian cancer: is functional information really needed?
Ovarian cancer (OC) often presents at an advanced stage with frequent relapses despite optimal treatment; thus, accurate staging and restaging are required for improving treatment outcomes and prognostication. Conventionally, staging of OC is performed using contrast-enhanced computed tomography (CT...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Medknow Publications
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/63376/ http://psasir.upm.edu.my/id/eprint/63376/1/Systematic%20Review%20on%20the%20Accuracy%20of%20Positron.pdf |
| _version_ | 1848854773496807424 |
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| author | Suppiah, Subapriya Wing, Liong Chang Hassan, Hasyma Abu Kaewput, Chalermrat Asri, Andi Anggeriana Andi Saad, Fathinul Fikri Ahmad Nordin, Abdul Jalil Vinjamuri, Sobhan |
| author_facet | Suppiah, Subapriya Wing, Liong Chang Hassan, Hasyma Abu Kaewput, Chalermrat Asri, Andi Anggeriana Andi Saad, Fathinul Fikri Ahmad Nordin, Abdul Jalil Vinjamuri, Sobhan |
| author_sort | Suppiah, Subapriya |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Ovarian cancer (OC) often presents at an advanced stage with frequent relapses despite optimal treatment; thus, accurate staging and restaging are required for improving treatment outcomes and prognostication. Conventionally, staging of OC is performed using contrast-enhanced computed tomography (CT). Nevertheless, recent advances in the field of hybrid imaging have made positron emission tomography/CT (PET/CT) and PET/magnetic resonance imaging (PET/MRI) as emerging potential noninvasive imaging tools for improved management of OC. Several studies have championed the role of PET/CT for the detection of recurrence and prognostication of OC. We provide a systematic review and meta-analysis of the latest publications regarding the role of molecular imaging in the management of OC. We retrieved 57 original research articles with one article having overlap in both diagnosis and staging; 10 articles (734 patients) regarding the role of PET/CT in diagnosis of OC; 12 articles (604 patients) regarding staging of OC; 22 studies (1429 patients) for detection of recurrence; and 13 articles for prognostication and assessment of treatment response. We calculated pooled sensitivity and specificity of PET/CT performance in various aspects of imaging of OC. We also discussed the emerging role of PET/MRI in the management of OC. We aim to give the readers and objective overview on the role of molecular imaging in the management of OC. |
| first_indexed | 2025-11-15T11:15:12Z |
| format | Article |
| id | upm-63376 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:15:12Z |
| publishDate | 2017 |
| publisher | Medknow Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-633762018-10-16T09:25:04Z http://psasir.upm.edu.my/id/eprint/63376/ Systematic review on the accuracy of positron emission tomography/computed tomography and positron emission tomography/magnetic resonance imaging in the management of ovarian cancer: is functional information really needed? Suppiah, Subapriya Wing, Liong Chang Hassan, Hasyma Abu Kaewput, Chalermrat Asri, Andi Anggeriana Andi Saad, Fathinul Fikri Ahmad Nordin, Abdul Jalil Vinjamuri, Sobhan Ovarian cancer (OC) often presents at an advanced stage with frequent relapses despite optimal treatment; thus, accurate staging and restaging are required for improving treatment outcomes and prognostication. Conventionally, staging of OC is performed using contrast-enhanced computed tomography (CT). Nevertheless, recent advances in the field of hybrid imaging have made positron emission tomography/CT (PET/CT) and PET/magnetic resonance imaging (PET/MRI) as emerging potential noninvasive imaging tools for improved management of OC. Several studies have championed the role of PET/CT for the detection of recurrence and prognostication of OC. We provide a systematic review and meta-analysis of the latest publications regarding the role of molecular imaging in the management of OC. We retrieved 57 original research articles with one article having overlap in both diagnosis and staging; 10 articles (734 patients) regarding the role of PET/CT in diagnosis of OC; 12 articles (604 patients) regarding staging of OC; 22 studies (1429 patients) for detection of recurrence; and 13 articles for prognostication and assessment of treatment response. We calculated pooled sensitivity and specificity of PET/CT performance in various aspects of imaging of OC. We also discussed the emerging role of PET/MRI in the management of OC. We aim to give the readers and objective overview on the role of molecular imaging in the management of OC. Medknow Publications 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/63376/1/Systematic%20Review%20on%20the%20Accuracy%20of%20Positron.pdf Suppiah, Subapriya and Wing, Liong Chang and Hassan, Hasyma Abu and Kaewput, Chalermrat and Asri, Andi Anggeriana Andi and Saad, Fathinul Fikri Ahmad and Nordin, Abdul Jalil and Vinjamuri, Sobhan (2017) Systematic review on the accuracy of positron emission tomography/computed tomography and positron emission tomography/magnetic resonance imaging in the management of ovarian cancer: is functional information really needed? World Journal of Nuclear Medicine, 16 (3). pp. 176-185. ISSN 1450-1147; ESSN: 1607-3312 http://www.wjnm.org/article.asp?issn=1450-1147;year=2017;volume=16;issue=3;spage=176;epage=185;aulast=Suppiah 10.4103/wjnm.WJNM_31_1 |
| spellingShingle | Suppiah, Subapriya Wing, Liong Chang Hassan, Hasyma Abu Kaewput, Chalermrat Asri, Andi Anggeriana Andi Saad, Fathinul Fikri Ahmad Nordin, Abdul Jalil Vinjamuri, Sobhan Systematic review on the accuracy of positron emission tomography/computed tomography and positron emission tomography/magnetic resonance imaging in the management of ovarian cancer: is functional information really needed? |
| title | Systematic review on the accuracy of positron emission tomography/computed tomography and positron emission tomography/magnetic resonance imaging in the management of ovarian cancer: is functional information really needed? |
| title_full | Systematic review on the accuracy of positron emission tomography/computed tomography and positron emission tomography/magnetic resonance imaging in the management of ovarian cancer: is functional information really needed? |
| title_fullStr | Systematic review on the accuracy of positron emission tomography/computed tomography and positron emission tomography/magnetic resonance imaging in the management of ovarian cancer: is functional information really needed? |
| title_full_unstemmed | Systematic review on the accuracy of positron emission tomography/computed tomography and positron emission tomography/magnetic resonance imaging in the management of ovarian cancer: is functional information really needed? |
| title_short | Systematic review on the accuracy of positron emission tomography/computed tomography and positron emission tomography/magnetic resonance imaging in the management of ovarian cancer: is functional information really needed? |
| title_sort | systematic review on the accuracy of positron emission tomography/computed tomography and positron emission tomography/magnetic resonance imaging in the management of ovarian cancer: is functional information really needed? |
| url | http://psasir.upm.edu.my/id/eprint/63376/ http://psasir.upm.edu.my/id/eprint/63376/ http://psasir.upm.edu.my/id/eprint/63376/ http://psasir.upm.edu.my/id/eprint/63376/1/Systematic%20Review%20on%20the%20Accuracy%20of%20Positron.pdf |