Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient

A 61-year-old Punjabi female patient presented with six months history of mild abdominal discomfort with bloody diarrhea. She did not have underlying chronic medical illness; she neither took steroid nor immunosuppressant. She was found anemic, thrombocytosis, and elevated C-reactive protein. Colono...

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Main Authors: Jin, Yu Chieng, Sugumaran, Yasotha, Adzman, Sellymiah, Yan, Pan
Format: Article
Language:English
Published: PAGEPress Publications 2017
Online Access:http://psasir.upm.edu.my/id/eprint/63349/
http://psasir.upm.edu.my/id/eprint/63349/1/Synchronous%20cytomegalovirus%20infection%20in%20a%20newly%20diagnosed%20ulcerative%20colitis%20patient.pdf
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author Jin, Yu Chieng
Sugumaran, Yasotha
Adzman, Sellymiah
Yan, Pan
author_facet Jin, Yu Chieng
Sugumaran, Yasotha
Adzman, Sellymiah
Yan, Pan
author_sort Jin, Yu Chieng
building UPM Institutional Repository
collection Online Access
description A 61-year-old Punjabi female patient presented with six months history of mild abdominal discomfort with bloody diarrhea. She did not have underlying chronic medical illness; she neither took steroid nor immunosuppressant. She was found anemic, thrombocytosis, and elevated C-reactive protein. Colonoscopy showed moderate left sided colitis, with histopathology evidence of ulcerative colitis (UC) with cytomegalovirus (CMV) infection. Her serum anti-CMV IgM antibody was detected. She was treated with intravenous ganciclovir, together with 5-ASA and tapering dose of steroid. Anemia was corrected. Subsequent clinic reviews and follow up endoscopies showed dramatically improvement. CMV colitis should be considered for the patients presenting with moderate to severe UC. Early prescription of antiviral would be beneficial in the treatment of flare of UC.
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spelling upm-633492018-10-16T00:32:46Z http://psasir.upm.edu.my/id/eprint/63349/ Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient Jin, Yu Chieng Sugumaran, Yasotha Adzman, Sellymiah Yan, Pan A 61-year-old Punjabi female patient presented with six months history of mild abdominal discomfort with bloody diarrhea. She did not have underlying chronic medical illness; she neither took steroid nor immunosuppressant. She was found anemic, thrombocytosis, and elevated C-reactive protein. Colonoscopy showed moderate left sided colitis, with histopathology evidence of ulcerative colitis (UC) with cytomegalovirus (CMV) infection. Her serum anti-CMV IgM antibody was detected. She was treated with intravenous ganciclovir, together with 5-ASA and tapering dose of steroid. Anemia was corrected. Subsequent clinic reviews and follow up endoscopies showed dramatically improvement. CMV colitis should be considered for the patients presenting with moderate to severe UC. Early prescription of antiviral would be beneficial in the treatment of flare of UC. PAGEPress Publications 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/63349/1/Synchronous%20cytomegalovirus%20infection%20in%20a%20newly%20diagnosed%20ulcerative%20colitis%20patient.pdf Jin, Yu Chieng and Sugumaran, Yasotha and Adzman, Sellymiah and Yan, Pan (2017) Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient. Gastroenterology Insights, 8 (1). 49 - 50. ISSN ISSN: 2036-7414; ESSN: 2036-7422 https://www.pagepress.org/journals/index.php/gi/article/view/6886 10.4081/gi.2017.6886
spellingShingle Jin, Yu Chieng
Sugumaran, Yasotha
Adzman, Sellymiah
Yan, Pan
Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient
title Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient
title_full Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient
title_fullStr Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient
title_full_unstemmed Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient
title_short Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient
title_sort synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient
url http://psasir.upm.edu.my/id/eprint/63349/
http://psasir.upm.edu.my/id/eprint/63349/
http://psasir.upm.edu.my/id/eprint/63349/
http://psasir.upm.edu.my/id/eprint/63349/1/Synchronous%20cytomegalovirus%20infection%20in%20a%20newly%20diagnosed%20ulcerative%20colitis%20patient.pdf