Prevalence and molecular characterisation of Schistosoma haematobium among primary school children in Kebbi State, Nigeria
Schistosomiasis is the major source of morbidity in Sub-Saharan Africa and Asia. It is estimated that 207 million people are infected, of which 97% are in Africa. The aim of this study was the determining of prevalence as well as the phylogeny of S. haematobium among school children in Argungu Emira...
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| Format: | Article |
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Polish Parasitological Society
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/62843/ http://psasir.upm.edu.my/id/eprint/62843/1/Prevalence%20and%20molecular%20.pdf |
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| author | Umar, Shuaibu Shinkafi, Saadatu Haruna Hudu, Shuaibu Abdullahi Neela, Vasantha Kumari Subbiah, Suresh Kumar Amin Nordin, Syafinaz Osman, Malina |
| author_facet | Umar, Shuaibu Shinkafi, Saadatu Haruna Hudu, Shuaibu Abdullahi Neela, Vasantha Kumari Subbiah, Suresh Kumar Amin Nordin, Syafinaz Osman, Malina |
| author_sort | Umar, Shuaibu |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Schistosomiasis is the major source of morbidity in Sub-Saharan Africa and Asia. It is estimated that 207 million people are infected, of which 97% are in Africa. The aim of this study was the determining of prevalence as well as the phylogeny of S. haematobium among school children in Argungu Emirate, Kebbi State Nigeria. A total of 325 urine samples was collected from school children between 7 to 14 years. S. heamatobium eggs was examined under dissecting microscope and DNA was extracted from urine sample and COX1 gene was amplified by nested PCR. The PCR products were purified, sequenced and analysed. This study showed a prevalence of 32.09%, with male pupils having the highest prevalence. S. haematobium infections in children who fetch water in the river have 24 times higher risk of being infected while those who bath in the river have 158 times higher risk of being infected. Our sequences were phylogenetically related to S. haematobium isolate U82266 from Kenya and consistence with the predominant species in Africa. This was the first S. haematobium and S. mansoni co-infection reported in Nigeria. S. haematobium infection is prevalent among school age and significantly associated with water contact. |
| first_indexed | 2025-11-15T11:13:40Z |
| format | Article |
| id | upm-62843 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:13:40Z |
| publishDate | 2017 |
| publisher | Polish Parasitological Society |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-628432022-11-21T01:46:07Z http://psasir.upm.edu.my/id/eprint/62843/ Prevalence and molecular characterisation of Schistosoma haematobium among primary school children in Kebbi State, Nigeria Umar, Shuaibu Shinkafi, Saadatu Haruna Hudu, Shuaibu Abdullahi Neela, Vasantha Kumari Subbiah, Suresh Kumar Amin Nordin, Syafinaz Osman, Malina Schistosomiasis is the major source of morbidity in Sub-Saharan Africa and Asia. It is estimated that 207 million people are infected, of which 97% are in Africa. The aim of this study was the determining of prevalence as well as the phylogeny of S. haematobium among school children in Argungu Emirate, Kebbi State Nigeria. A total of 325 urine samples was collected from school children between 7 to 14 years. S. heamatobium eggs was examined under dissecting microscope and DNA was extracted from urine sample and COX1 gene was amplified by nested PCR. The PCR products were purified, sequenced and analysed. This study showed a prevalence of 32.09%, with male pupils having the highest prevalence. S. haematobium infections in children who fetch water in the river have 24 times higher risk of being infected while those who bath in the river have 158 times higher risk of being infected. Our sequences were phylogenetically related to S. haematobium isolate U82266 from Kenya and consistence with the predominant species in Africa. This was the first S. haematobium and S. mansoni co-infection reported in Nigeria. S. haematobium infection is prevalent among school age and significantly associated with water contact. Polish Parasitological Society 2017-03 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/62843/1/Prevalence%20and%20molecular%20.pdf Umar, Shuaibu and Shinkafi, Saadatu Haruna and Hudu, Shuaibu Abdullahi and Neela, Vasantha Kumari and Subbiah, Suresh Kumar and Amin Nordin, Syafinaz and Osman, Malina (2017) Prevalence and molecular characterisation of Schistosoma haematobium among primary school children in Kebbi State, Nigeria. Annals of parasitology, 63 (2). 133 - 139. ISSN 2299-0631; ESSN: 2300-6706 https://www.annals-parasitology.eu/go.live.php/PL-H180/2017-vol-63-2.html 10.17420/ap6302.97 |
| spellingShingle | Umar, Shuaibu Shinkafi, Saadatu Haruna Hudu, Shuaibu Abdullahi Neela, Vasantha Kumari Subbiah, Suresh Kumar Amin Nordin, Syafinaz Osman, Malina Prevalence and molecular characterisation of Schistosoma haematobium among primary school children in Kebbi State, Nigeria |
| title | Prevalence and molecular characterisation of Schistosoma haematobium among primary school children in Kebbi State, Nigeria |
| title_full | Prevalence and molecular characterisation of Schistosoma haematobium among primary school children in Kebbi State, Nigeria |
| title_fullStr | Prevalence and molecular characterisation of Schistosoma haematobium among primary school children in Kebbi State, Nigeria |
| title_full_unstemmed | Prevalence and molecular characterisation of Schistosoma haematobium among primary school children in Kebbi State, Nigeria |
| title_short | Prevalence and molecular characterisation of Schistosoma haematobium among primary school children in Kebbi State, Nigeria |
| title_sort | prevalence and molecular characterisation of schistosoma haematobium among primary school children in kebbi state, nigeria |
| url | http://psasir.upm.edu.my/id/eprint/62843/ http://psasir.upm.edu.my/id/eprint/62843/ http://psasir.upm.edu.my/id/eprint/62843/ http://psasir.upm.edu.my/id/eprint/62843/1/Prevalence%20and%20molecular%20.pdf |