Neuro-therapeutic benefits of Centella asiatica on some neurodegenerative diseases: a review
Medicinal herbalism has become popular because of its documented efficacy, synergistic interactions against complex conditions and lesser side effects. CA (CA) is a traditional Ayurveda medicine widely used in India, China, and Malaysia and across countries in south-eastern Asia for treating a range...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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RJPBCS
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/62523/ http://psasir.upm.edu.my/id/eprint/62523/1/NEURO.pdf |
| _version_ | 1848854635806195712 |
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| author | Chiroma, Samaila Musa Mohd Moklas, Mohamad Aris Mat Taib, Che Norma Baharuldin, Mohamad Taufik Hidayat Jagadeesan, Saravanan Amom, Zulkhairi Ibrahim, Bulama |
| author_facet | Chiroma, Samaila Musa Mohd Moklas, Mohamad Aris Mat Taib, Che Norma Baharuldin, Mohamad Taufik Hidayat Jagadeesan, Saravanan Amom, Zulkhairi Ibrahim, Bulama |
| author_sort | Chiroma, Samaila Musa |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Medicinal herbalism has become popular because of its documented efficacy, synergistic interactions against complex conditions and lesser side effects. CA (CA) is a traditional Ayurveda medicine widely used in India, China, and Malaysia and across countries in south-eastern Asia for treating a range of diseases. The whole plant or its parts (leaf or roots) are used for medicinal purpose and its chemical constituents have been proven scientifically to have neuro-protective, wound healing, anti-inflammatory and antioxidants activities. In this review we have retrieved and evaluated available literatures on neuro-therapeutic properties of CA on neurotoxic and transgenic models of Alzheimer’s diseases (AD), Parkinson’s disease (PD) and Huntington’s disease (HD). The extract was found to have neuroprotective ability through modifying a key signaling pathways and events concerned with neuro-degeneration. Further research is required to discover more bioactive compounds of CA and their exact mode of action. |
| first_indexed | 2025-11-15T11:13:00Z |
| format | Article |
| id | upm-62523 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:13:00Z |
| publishDate | 2017 |
| publisher | RJPBCS |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-625232020-12-03T20:37:59Z http://psasir.upm.edu.my/id/eprint/62523/ Neuro-therapeutic benefits of Centella asiatica on some neurodegenerative diseases: a review Chiroma, Samaila Musa Mohd Moklas, Mohamad Aris Mat Taib, Che Norma Baharuldin, Mohamad Taufik Hidayat Jagadeesan, Saravanan Amom, Zulkhairi Ibrahim, Bulama Medicinal herbalism has become popular because of its documented efficacy, synergistic interactions against complex conditions and lesser side effects. CA (CA) is a traditional Ayurveda medicine widely used in India, China, and Malaysia and across countries in south-eastern Asia for treating a range of diseases. The whole plant or its parts (leaf or roots) are used for medicinal purpose and its chemical constituents have been proven scientifically to have neuro-protective, wound healing, anti-inflammatory and antioxidants activities. In this review we have retrieved and evaluated available literatures on neuro-therapeutic properties of CA on neurotoxic and transgenic models of Alzheimer’s diseases (AD), Parkinson’s disease (PD) and Huntington’s disease (HD). The extract was found to have neuroprotective ability through modifying a key signaling pathways and events concerned with neuro-degeneration. Further research is required to discover more bioactive compounds of CA and their exact mode of action. RJPBCS 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/62523/1/NEURO.pdf Chiroma, Samaila Musa and Mohd Moklas, Mohamad Aris and Mat Taib, Che Norma and Baharuldin, Mohamad Taufik Hidayat and Jagadeesan, Saravanan and Amom, Zulkhairi and Ibrahim, Bulama (2017) Neuro-therapeutic benefits of Centella asiatica on some neurodegenerative diseases: a review. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 8 (6). 549 - 556. ISSN 0975-8585 https://www.researchgate.net/publication/331356684_Neuro-therapeutic_Benefits_of_Centella_asiatica_on_Some_Neurodegenerative_Diseases_A_Review/link/5c7577ca458515831f728cbc/download |
| spellingShingle | Chiroma, Samaila Musa Mohd Moklas, Mohamad Aris Mat Taib, Che Norma Baharuldin, Mohamad Taufik Hidayat Jagadeesan, Saravanan Amom, Zulkhairi Ibrahim, Bulama Neuro-therapeutic benefits of Centella asiatica on some neurodegenerative diseases: a review |
| title | Neuro-therapeutic benefits of Centella asiatica on some neurodegenerative diseases: a review |
| title_full | Neuro-therapeutic benefits of Centella asiatica on some neurodegenerative diseases: a review |
| title_fullStr | Neuro-therapeutic benefits of Centella asiatica on some neurodegenerative diseases: a review |
| title_full_unstemmed | Neuro-therapeutic benefits of Centella asiatica on some neurodegenerative diseases: a review |
| title_short | Neuro-therapeutic benefits of Centella asiatica on some neurodegenerative diseases: a review |
| title_sort | neuro-therapeutic benefits of centella asiatica on some neurodegenerative diseases: a review |
| url | http://psasir.upm.edu.my/id/eprint/62523/ http://psasir.upm.edu.my/id/eprint/62523/ http://psasir.upm.edu.my/id/eprint/62523/1/NEURO.pdf |