Molecular cloning and expression analysis of Ganoderma boninense cyclophilins at different growth and infection stages

Oil palm is subjected to various diseases including Basal Stem Rot (BSR) which is mainly caused by the basidiomycetes fungi, Ganoderma. However, studies on the fungal infection mechanism especially at molecular level and the biological processes involved are still very limited. Fungal cyclophilin (C...

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Main Authors: Lim, Fook Hwa, Iskandar, Nor Fakhrana, Abd Rasid, Omar, Idris, Abu Seman, Ho, Chai Ling, Shaharuddin, Noor Azmi, Ahmad Parveez, Ghulam Kadir
Format: Article
Language:English
Published: Academic Press 2017
Online Access:http://psasir.upm.edu.my/id/eprint/62468/
http://psasir.upm.edu.my/id/eprint/62468/1/BASAL.pdf
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author Lim, Fook Hwa
Iskandar, Nor Fakhrana
Abd Rasid, Omar
Idris, Abu Seman
Ho, Chai Ling
Shaharuddin, Noor Azmi
Ahmad Parveez, Ghulam Kadir
author_facet Lim, Fook Hwa
Iskandar, Nor Fakhrana
Abd Rasid, Omar
Idris, Abu Seman
Ho, Chai Ling
Shaharuddin, Noor Azmi
Ahmad Parveez, Ghulam Kadir
author_sort Lim, Fook Hwa
building UPM Institutional Repository
collection Online Access
description Oil palm is subjected to various diseases including Basal Stem Rot (BSR) which is mainly caused by the basidiomycetes fungi, Ganoderma. However, studies on the fungal infection mechanism especially at molecular level and the biological processes involved are still very limited. Fungal cyclophilin (CYP) has been reported to be involved in fungal pathogenicity but involvement of CYP in the pathogenicity of Ganoderma boninense has not been revealed yet. The main objective of this study is to isolate cDNAs encoding CYP and to profile the expression level of these transcripts during infection stages of G. boninense. In this study, five full-length cDNAs encoding CYP were successfully isolated from G. boninense. They were classified as different family members of CYP because significant differences could be observed on their coding, 5′ or 3′ un-translated regions (UTRs). The expression of these five CYP transcripts in different type of G. boninense tissues and the infecting mycelia tissues was studied using real time quantitative PCR (qPCR). Based on the expression results and analysis, the potential functions of these CYP transcripts were predicted to be involved in the development of fruiting body (GbCYP201) and fungal stress response or pathogenicity (GbCYP203 and GbCYP205).
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spelling upm-624682021-04-30T05:48:42Z http://psasir.upm.edu.my/id/eprint/62468/ Molecular cloning and expression analysis of Ganoderma boninense cyclophilins at different growth and infection stages Lim, Fook Hwa Iskandar, Nor Fakhrana Abd Rasid, Omar Idris, Abu Seman Ho, Chai Ling Shaharuddin, Noor Azmi Ahmad Parveez, Ghulam Kadir Oil palm is subjected to various diseases including Basal Stem Rot (BSR) which is mainly caused by the basidiomycetes fungi, Ganoderma. However, studies on the fungal infection mechanism especially at molecular level and the biological processes involved are still very limited. Fungal cyclophilin (CYP) has been reported to be involved in fungal pathogenicity but involvement of CYP in the pathogenicity of Ganoderma boninense has not been revealed yet. The main objective of this study is to isolate cDNAs encoding CYP and to profile the expression level of these transcripts during infection stages of G. boninense. In this study, five full-length cDNAs encoding CYP were successfully isolated from G. boninense. They were classified as different family members of CYP because significant differences could be observed on their coding, 5′ or 3′ un-translated regions (UTRs). The expression of these five CYP transcripts in different type of G. boninense tissues and the infecting mycelia tissues was studied using real time quantitative PCR (qPCR). Based on the expression results and analysis, the potential functions of these CYP transcripts were predicted to be involved in the development of fruiting body (GbCYP201) and fungal stress response or pathogenicity (GbCYP203 and GbCYP205). Academic Press 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/62468/1/BASAL.pdf Lim, Fook Hwa and Iskandar, Nor Fakhrana and Abd Rasid, Omar and Idris, Abu Seman and Ho, Chai Ling and Shaharuddin, Noor Azmi and Ahmad Parveez, Ghulam Kadir (2017) Molecular cloning and expression analysis of Ganoderma boninense cyclophilins at different growth and infection stages. Physiological and Molecular Plant Pathology, 99. 31 - 40. ISSN 0885-5765; ESSN: 1096-1178 https://www.sciencedirect.com/science/article/pii/S0885576516300601 10.1016/j.pmpp.2016.05.005
spellingShingle Lim, Fook Hwa
Iskandar, Nor Fakhrana
Abd Rasid, Omar
Idris, Abu Seman
Ho, Chai Ling
Shaharuddin, Noor Azmi
Ahmad Parveez, Ghulam Kadir
Molecular cloning and expression analysis of Ganoderma boninense cyclophilins at different growth and infection stages
title Molecular cloning and expression analysis of Ganoderma boninense cyclophilins at different growth and infection stages
title_full Molecular cloning and expression analysis of Ganoderma boninense cyclophilins at different growth and infection stages
title_fullStr Molecular cloning and expression analysis of Ganoderma boninense cyclophilins at different growth and infection stages
title_full_unstemmed Molecular cloning and expression analysis of Ganoderma boninense cyclophilins at different growth and infection stages
title_short Molecular cloning and expression analysis of Ganoderma boninense cyclophilins at different growth and infection stages
title_sort molecular cloning and expression analysis of ganoderma boninense cyclophilins at different growth and infection stages
url http://psasir.upm.edu.my/id/eprint/62468/
http://psasir.upm.edu.my/id/eprint/62468/
http://psasir.upm.edu.my/id/eprint/62468/
http://psasir.upm.edu.my/id/eprint/62468/1/BASAL.pdf