Malignant melanoma of the uterus: a rare cause of postmenopausal bleeding

Background: Malignant melanoma of the uterus is a very rare disease entity bearing potentially serious consequences with an unpredictable and poor prognosis. Case: A 64-year-old woman who had a longstanding, slow-growing blackish mass of the right big toe for more than a decade, presented with postm...

Full description

Bibliographic Details
Main Authors: Abdul Hamid, Habibah, Raja Gopal, Navarasi S., Ibrahim, Maryasalwati, Awang Soh, Nor Hashliena, Wan Ghazali, Wan Ahmad Hazim
Format: Article
Language:English
Published: Mary Ann Liebert 2017
Online Access:http://psasir.upm.edu.my/id/eprint/62342/
http://psasir.upm.edu.my/id/eprint/62342/1/Malignant%20melanoma%20of%20the%20uterus.pdf
_version_ 1848854611112230912
author Abdul Hamid, Habibah
Raja Gopal, Navarasi S.
Ibrahim, Maryasalwati
Awang Soh, Nor Hashliena
Wan Ghazali, Wan Ahmad Hazim
author_facet Abdul Hamid, Habibah
Raja Gopal, Navarasi S.
Ibrahim, Maryasalwati
Awang Soh, Nor Hashliena
Wan Ghazali, Wan Ahmad Hazim
author_sort Abdul Hamid, Habibah
building UPM Institutional Repository
collection Online Access
description Background: Malignant melanoma of the uterus is a very rare disease entity bearing potentially serious consequences with an unpredictable and poor prognosis. Case: A 64-year-old woman who had a longstanding, slow-growing blackish mass of the right big toe for more than a decade, presented with postmenopausal bleeding. Histopathologic examination confirmed the diagnosis of a likely secondary malignant melanoma of the uterus. Results: She was treated successfully without any complications via total laparoscopic hysterectomy and bilateral salpingo-oophorectomy (TLHBSO). Even though malignant melanoma of the uterus has a poor prognosis, the patient was alive and disease-free at a 1-year regular follow-up. Conclusions: A malignant melanoma of the uterus is very rare and has a poor prognosis. However, laparoscopic excision of the uterus and adjacent organs in selected patients could be a superior option, especially in terms of rapid recovery and minimal tumor spillage. A combined multidisciplinary approach is highly recommended for dealing with malignant melanoma–related diseases for optimal care and a better clinical outcome.
first_indexed 2025-11-15T11:12:37Z
format Article
id upm-62342
institution Universiti Putra Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T11:12:37Z
publishDate 2017
publisher Mary Ann Liebert
recordtype eprints
repository_type Digital Repository
spelling upm-623422020-01-07T03:20:38Z http://psasir.upm.edu.my/id/eprint/62342/ Malignant melanoma of the uterus: a rare cause of postmenopausal bleeding Abdul Hamid, Habibah Raja Gopal, Navarasi S. Ibrahim, Maryasalwati Awang Soh, Nor Hashliena Wan Ghazali, Wan Ahmad Hazim Background: Malignant melanoma of the uterus is a very rare disease entity bearing potentially serious consequences with an unpredictable and poor prognosis. Case: A 64-year-old woman who had a longstanding, slow-growing blackish mass of the right big toe for more than a decade, presented with postmenopausal bleeding. Histopathologic examination confirmed the diagnosis of a likely secondary malignant melanoma of the uterus. Results: She was treated successfully without any complications via total laparoscopic hysterectomy and bilateral salpingo-oophorectomy (TLHBSO). Even though malignant melanoma of the uterus has a poor prognosis, the patient was alive and disease-free at a 1-year regular follow-up. Conclusions: A malignant melanoma of the uterus is very rare and has a poor prognosis. However, laparoscopic excision of the uterus and adjacent organs in selected patients could be a superior option, especially in terms of rapid recovery and minimal tumor spillage. A combined multidisciplinary approach is highly recommended for dealing with malignant melanoma–related diseases for optimal care and a better clinical outcome. Mary Ann Liebert 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/62342/1/Malignant%20melanoma%20of%20the%20uterus.pdf Abdul Hamid, Habibah and Raja Gopal, Navarasi S. and Ibrahim, Maryasalwati and Awang Soh, Nor Hashliena and Wan Ghazali, Wan Ahmad Hazim (2017) Malignant melanoma of the uterus: a rare cause of postmenopausal bleeding. Journal of Gynecologic Surgery, 33 (4). 149 - 152. ISSN 1042-4067; ESSN: 1557-7724 https://www.liebertpub.com/doi/10.1089/gyn.2016.0125 10.1089/gyn.2016.0125
spellingShingle Abdul Hamid, Habibah
Raja Gopal, Navarasi S.
Ibrahim, Maryasalwati
Awang Soh, Nor Hashliena
Wan Ghazali, Wan Ahmad Hazim
Malignant melanoma of the uterus: a rare cause of postmenopausal bleeding
title Malignant melanoma of the uterus: a rare cause of postmenopausal bleeding
title_full Malignant melanoma of the uterus: a rare cause of postmenopausal bleeding
title_fullStr Malignant melanoma of the uterus: a rare cause of postmenopausal bleeding
title_full_unstemmed Malignant melanoma of the uterus: a rare cause of postmenopausal bleeding
title_short Malignant melanoma of the uterus: a rare cause of postmenopausal bleeding
title_sort malignant melanoma of the uterus: a rare cause of postmenopausal bleeding
url http://psasir.upm.edu.my/id/eprint/62342/
http://psasir.upm.edu.my/id/eprint/62342/
http://psasir.upm.edu.my/id/eprint/62342/
http://psasir.upm.edu.my/id/eprint/62342/1/Malignant%20melanoma%20of%20the%20uterus.pdf