Improved in vivo efficacy of anti-hypertensive biopeptides encapsulated in chitosan nanoparticles fabricated by ionotropic gelation on spontaneously hypertensive rats

QR Code

Improved in vivo efficacy of anti-hypertensive biopeptides encapsulated in chitosan nanoparticles fabricated by ionotropic gelation on spontaneously hypertensive rats

Recent biotechnological advances in the food industry have led to the enzymatic production of angiotensin I-converting enzyme (ACE)-inhibitory biopeptides with a strong blood pressure lowering effect from different food proteins. However, the safe oral administration of biopeptides is impeded by the...

Full description

Bibliographic Details
Main Authors:	Auwal, Shehu Muhammad, Zarei, Mohammad, Tan, Chin Ping, Basri, Mahiran, Saari, Nazamid
Format:	Article
Language:	English
Published:	MDPI 2017
Online Access:	http://psasir.upm.edu.my/id/eprint/62117/ http://psasir.upm.edu.my/id/eprint/62117/1/Improved%20in%20vivo%20efficacy.pdf

Similar Items

Enhanced physicochemical stability and efficacy of angiotensin I-converting enzyme (ACE) - inhibitory biopeptides by chitosan nanoparticles optimized using Box-Behnken design
by: Auwal, Shehu Muhammad, et al.
Published: (2018)

Safety and efficacy of oral epigallocatechin gallate in attenuating hypertension in spontaneously hypertensive rats via modulation of the intrarenal renin-angiotensin system
by: Parn, Kim Wai
Published: (2023)

The antihypertensive efficacy of Piper sarmentosum aqueous extract as compared to perindopril in spontaneously hypertensive rats
by: Hashim Fauzy, Fatimatuzzahra, et al.
Published: (2019)

Syzygium polyanthum protects against hypertensive induced kidney damage in spontaneous hypertensive rat model
by: Liza Noordin,, et al.
Published: (2021)

Evaluation of aqueous extract of syzygium polyanthum leaves as anti-hypertensive agent in spontaneous hypertensive rat (SHR)
by: Ramli, Nurul Syahida
Published: (2021)

The role of oxidative stress and the effect of antioxidant (vitamin e & melatonin) in the development of hypertension in spontaneously hypertensive rats
by: Sirajudeen, K.N.S.
Published: (2012)

Effects of cross-fostering and Melatonin supplementation on the Development of hypertension and Renal antioxidant/oxidant system in Spontaneously hypertensive rats.
by: Lee, Siew Keah
Published: (2011)

Time-restricted feeding attenuated hypertension-induced cardiac remodeling by modulating autophagy levels in spontaneously hypertensive rats
by: Yi, Xin, et al.
Published: (2025)

Effects of durian fruit on blood pressure of spontaneously hypertensive rats
by: Malina Jasamai,, et al.
Published: (2018)

The effects of antihypertensive drugs and antioxidant supplement on the development and progression of hypertension, renal oxidative stress and damage in spontaneously hypertensive rats
by: Govindasamy , Chandran
Published: (2017)

Recent advances in food biopeptides: production, biological functionalities and therapeutic applications
by: Saadi, Sami, et al.
Published: (2015)

Recent advances in food biopeptides: production, biological functionalities and threapeutic applications
by: Saadi, Sami, et al.
Published: (2015)

Amelioration of aorta morphology in spontaneous hypertensive rat (SHR) by syzygium polyanthum
by: Ismail, Azlini, et al.
Published: (2018)

Morphological evaluation of aortic vessel in Spontaneously Hypertensive Rat (SHR) Models
by: Ramli, Nurul Syahida, et al.
Published: (2019)

Association of 8-isoprostanes level and renal impairment in spontaneously hypertensive rats
by: Wahab, Nor Akmal
Published: (2004)

Association of malondialdehyde(mda) level and renal impairment in spontaneously hypertensive rats
by: Wahab, Nor Akmal
Published: (2004)

Mechanism of anti-hypertensive effect of standardised aqueous ethanolic extract of Ficus deltoidea Trengganuensis in spontaneously hypertensive rats / Zurain Radjeni
by: Radjeni, Zurain
Published: (2019)

Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
by: Sundaram , Arunkumar
Published: (2010)

Optimization, physicochemical stability and in vivo study of alginate-chitosan composites as nanocarriers for low molecular weight angiotensin I-converting enzyme (ACE)-inhibitory peptide
by: Auwal, Shehu Muhammad, et al.
Published: (2024)

Amelioration of aorta morphology in a spontaneous hypertensive rat (shr) by Syzygium polyanthum
by: Ismail, Azlini, et al.
Published: (2018)

Antihypertensive and vasoprotective effects of epigallocatechin-3-gallate(EGCG) in spontaneously hypertensive rats
by: Khor, Yucinda Yee Yan
Published: (2024)

Efficacy and adverse effects of doxazosin in the treatment of hypertension
by: Sirisinghe, Roland G.
Published: (1999)

Antihypertensive activities of standardised Moringa oleifera Lam. (Merunggai) extracts in spontaneously hypertensive rats
by: Endang Kumolosasi,, et al.
Published: (2021)

S. polyanthum leaves aqueous extracts as potential antihypertensive agent in spontaneous hypertensive rat model
by: Baharun, Bibi Nur Bazlini
Published: (2018)

Peripheral Antihypertensive Mechanisms Of Zing/Ber Officinale Var. Rubrumin Spontaneously Hypertensive Rats
by: Razali, Nadiah
Published: (2022)

Lifestyle management of hypertension: International Society of Hypertension position paper endorsed by the World Hypertension League and European Society of Hypertension
by: Charchar, Fadi J., et al.
Published: (2024)

Potentiality of self-cloned Lactobacillus plantarum Taj-Apis362 for enhancing GABA production in yogurt under glucose induction: optimization and its cardiovascular effect on spontaneous hypertensive rats
by: Hussin, Farah Salina, et al.
Published: (2020)

The use of piper sarmentosum leaves aqueous extract (kadukmy™) as antihypertensive agent in spontaneous hypertensive rats
by: Mohd Zainudin, Maizura, et al.
Published: (2015)

Piper sarmentosum leaves aqueous extract attenuates vascular endothelial dysfunction in spontaneously hypertensive rats
by: Hashim Fauzy, Fatimatuzzahra, et al.
Published: (2019)

The effect of chronic 1,2,3,4-Tetrahydroisoquinolines administration in young spontaneously hypertensive rats
by: Abdullah, Aszrin, et al.
Published: (2011)

Effect of Clonidine (an Antihypertensive Drug) Treatment on Oxidative Stress Markers in the Heart of Spontaneously Hypertensive Rats
by: Nik Yusoff, Nik Syamimi, et al.
Published: (2013)

Investigation of the mechanism underlying the vasoprotective effects of red yeast rice extract in spontaneously hypertensive rats
by: Tan, Jiunn Jye
Published: (2024)

Antihypertensive And Renoprotective Effects Of Hibiscus Sabdariffa Extracts On Doca-Salt Induced And Spontaneously Hypertensive Rats
by: Ho, Yoke Mei
Published: (2022)

Efficacy of cupping in the treatment of hypertension disease using graph colouring
by: Elizabeth, Marta, et al.
Published: (2019)

Winged bean [Psophorcarpus tetragonolobus (L.) DC] seeds as an underutilised plant source of bifunctional proteolysate and biopeptides
by: Chay, Shyan Yea, et al.
Published: (2014)

Effects of different types of Syzygium Polyanthum leaves extracts on blood pressure of anaesthetized Spontaneously Hypertensive rats
by: Ismail, Azlini, et al.
Published: (2017)

Antihypertensive effect of fractions derived from an aqueous extract of Syzygium polyanthum on anaesthetized spontaneously hypertensive rats
by: Abd Rahim, Erlena Nor Asmira, et al.
Published: (2018)

Antihypertensive effect of fractions derived from aqueous extract of syzygium polyanthum on anaesthetized spontaneously hypertensive rats
by: Abd Rahim, Erlena Nor Asmira, et al.
Published: (2018)

Factors regulating nitric oxide production in spontaneously hypertensive rats treated with piper sarmentosum aqueous extract
by: Mohd Zainudin, Maizura, et al.
Published: (2019)

Effects of different types of Syzygium Polyanthum leaves extracts on blood pressure of anaesthetized Spontaneously Hypertensive rats
by: Ismail, Azlini, et al.
Published: (2019)