Group B adenovirus enadenotucirev infects polarised colorectal cancer cells efficiently from the basolateral surface expected to be encountered during intravenous delivery to treat disseminated cancer

Group B adenovirus enadenotucirev infects polarised colorectal cancer cells efficiently from the basolateral surface expected to be encountered during intravenous delivery to treat disseminated cancer

Enadenotucirev (EnAd) is a group B oncolytic adenovirus developed for systemic delivery and currently undergoing clinical evaluation for advanced cancer therapy. For differentiated carcinomas, systemic delivery would likely expose virus particles to the basolateral surface of cancer cells rather tha...

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Bibliographic Details
Main Authors: Chia, Suet Lin, Lei, Janet, Ferguson, David J. P., Dyer, Arthur, Fishera, Kerry D., Seymour, Leonard W.
Format: Article
Language:English
Published: Elsevier 2017
Online Access:http://psasir.upm.edu.my/id/eprint/61987/
http://psasir.upm.edu.my/id/eprint/61987/1/Group%20B%20adenovirus%20enadenotucirev%20infects%20polarised%20colorectal%20cancer%20cells%20.pdf

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