Green microwave-assisted combustion synthesis of Zinc oxide nanoparticles with Citrullus colocynthis (L.) Schrad: characterization and biomedical applications
In this paper, a green microwave-assisted combustion approach to synthesize ZnO-NPs using zinc nitrate and Citrullus colocynthis (L.) Schrad (fruit, seed and pulp) extracts as bio-fuels is reported. The structure, optical, and colloidal properties of the synthesized ZnO-NP samples were studied. Resu...
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| Format: | Article |
| Language: | English |
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MDPI
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/61978/ http://psasir.upm.edu.my/id/eprint/61978/1/Green%20microwave-assisted%20combustion%20synthesis%20of%20Zinc%20oxide.pdf |
| _version_ | 1848854530410676224 |
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| author | Azizi, Susan Mohamad, Rosfarizan Shahri, Mahnaz Mahdavi |
| author_facet | Azizi, Susan Mohamad, Rosfarizan Shahri, Mahnaz Mahdavi |
| author_sort | Azizi, Susan |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | In this paper, a green microwave-assisted combustion approach to synthesize ZnO-NPs using zinc nitrate and Citrullus colocynthis (L.) Schrad (fruit, seed and pulp) extracts as bio-fuels is reported. The structure, optical, and colloidal properties of the synthesized ZnO-NP samples were studied. Results illustrate that the morphology and particle size of the ZnO samples are different and depend on the bio-fuel. The XRD results revealed that hexagonal wurtzite ZnO-NPs with mean particle size of 27–85 nm were produced by different bio-fuels. The optical band gap was increased from 3.25 to 3.40 eV with the decreasing of particle size. FTIR results showed some differences in the surface structures of the as-synthesized ZnO-NP samples. This led to differences in the zeta potential, hydrodynamic size, and more significantly, antioxidant activity through scavenging of 1, 1-Diphenyl-2-picrylhydrazyl (DPPH) free radicals. In in vitro cytotoxicity studies on 3T3 cells, a dose dependent toxicity with non-toxic effect of concentration below 0.26 mg/mL was shown for ZnO-NP samples. Furthermore, the as-synthesized ZnO-NPs inhibited the growth of medically significant pathogenic gram-positive (Bacillus subtilis and Methicillin-resistant Staphylococcus aurous) and gram-negative (Peseudomonas aeruginosa and Escherichia coli) bacteria. This study provides a simple, green and efficient approach to produce ZnO nanoparticles for various applications. |
| first_indexed | 2025-11-15T11:11:20Z |
| format | Article |
| id | upm-61978 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:11:20Z |
| publishDate | 2017 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-619782019-03-12T02:26:17Z http://psasir.upm.edu.my/id/eprint/61978/ Green microwave-assisted combustion synthesis of Zinc oxide nanoparticles with Citrullus colocynthis (L.) Schrad: characterization and biomedical applications Azizi, Susan Mohamad, Rosfarizan Shahri, Mahnaz Mahdavi In this paper, a green microwave-assisted combustion approach to synthesize ZnO-NPs using zinc nitrate and Citrullus colocynthis (L.) Schrad (fruit, seed and pulp) extracts as bio-fuels is reported. The structure, optical, and colloidal properties of the synthesized ZnO-NP samples were studied. Results illustrate that the morphology and particle size of the ZnO samples are different and depend on the bio-fuel. The XRD results revealed that hexagonal wurtzite ZnO-NPs with mean particle size of 27–85 nm were produced by different bio-fuels. The optical band gap was increased from 3.25 to 3.40 eV with the decreasing of particle size. FTIR results showed some differences in the surface structures of the as-synthesized ZnO-NP samples. This led to differences in the zeta potential, hydrodynamic size, and more significantly, antioxidant activity through scavenging of 1, 1-Diphenyl-2-picrylhydrazyl (DPPH) free radicals. In in vitro cytotoxicity studies on 3T3 cells, a dose dependent toxicity with non-toxic effect of concentration below 0.26 mg/mL was shown for ZnO-NP samples. Furthermore, the as-synthesized ZnO-NPs inhibited the growth of medically significant pathogenic gram-positive (Bacillus subtilis and Methicillin-resistant Staphylococcus aurous) and gram-negative (Peseudomonas aeruginosa and Escherichia coli) bacteria. This study provides a simple, green and efficient approach to produce ZnO nanoparticles for various applications. MDPI 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/61978/1/Green%20microwave-assisted%20combustion%20synthesis%20of%20Zinc%20oxide.pdf Azizi, Susan and Mohamad, Rosfarizan and Shahri, Mahnaz Mahdavi (2017) Green microwave-assisted combustion synthesis of Zinc oxide nanoparticles with Citrullus colocynthis (L.) Schrad: characterization and biomedical applications. Molecules, 22 (2). pp. 1-13. ISSN 1420-3049 https://www.mdpi.com/1420-3049/22/2/301 10.3390/molecules22020301 |
| spellingShingle | Azizi, Susan Mohamad, Rosfarizan Shahri, Mahnaz Mahdavi Green microwave-assisted combustion synthesis of Zinc oxide nanoparticles with Citrullus colocynthis (L.) Schrad: characterization and biomedical applications |
| title | Green microwave-assisted combustion synthesis of Zinc oxide nanoparticles with Citrullus colocynthis (L.) Schrad: characterization and biomedical applications |
| title_full | Green microwave-assisted combustion synthesis of Zinc oxide nanoparticles with Citrullus colocynthis (L.) Schrad: characterization and biomedical applications |
| title_fullStr | Green microwave-assisted combustion synthesis of Zinc oxide nanoparticles with Citrullus colocynthis (L.) Schrad: characterization and biomedical applications |
| title_full_unstemmed | Green microwave-assisted combustion synthesis of Zinc oxide nanoparticles with Citrullus colocynthis (L.) Schrad: characterization and biomedical applications |
| title_short | Green microwave-assisted combustion synthesis of Zinc oxide nanoparticles with Citrullus colocynthis (L.) Schrad: characterization and biomedical applications |
| title_sort | green microwave-assisted combustion synthesis of zinc oxide nanoparticles with citrullus colocynthis (l.) schrad: characterization and biomedical applications |
| url | http://psasir.upm.edu.my/id/eprint/61978/ http://psasir.upm.edu.my/id/eprint/61978/ http://psasir.upm.edu.my/id/eprint/61978/ http://psasir.upm.edu.my/id/eprint/61978/1/Green%20microwave-assisted%20combustion%20synthesis%20of%20Zinc%20oxide.pdf |