Generation of transgenic rice expressing cyclotide precursor Oldenlandia affinis kalata B1 protein

Golden apple snail (Pomacea canaliculata) is a devastating pest on rice that causes heavy economic losses in South East Asia. In this study, we transformed mature seed-derived rice callus with plasmid containing Oldenlandia affinis kalata B1 (Oak1) gene encoding precursor's protein for potent m...

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Main Authors: Lim, Yi Yi, Lai, Kok Song
Format: Article
Language:English
Published: Pakistan Agricultural Scientists Forum 2017
Online Access:http://psasir.upm.edu.my/id/eprint/61949/
http://psasir.upm.edu.my/id/eprint/61949/1/Generation%20of%20transgenic%20rice%20expressing%20cyclotide%20precursor%20Oldenlandia%20affinis%20kalata%20B1%20protein.pdf
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author Lim, Yi Yi
Lai, Kok Song
author_facet Lim, Yi Yi
Lai, Kok Song
author_sort Lim, Yi Yi
building UPM Institutional Repository
collection Online Access
description Golden apple snail (Pomacea canaliculata) is a devastating pest on rice that causes heavy economic losses in South East Asia. In this study, we transformed mature seed-derived rice callus with plasmid containing Oldenlandia affinis kalata B1 (Oak1) gene encoding precursor's protein for potent molluscicidal agent of cyclotidekalata B1 targeting the golden apple snails. A total of 11 independent T0 transformants were recovered and 7 were positive Oak1transformants according to genomic PCR analysis. The Oak1 mRNA transcript was successfully detected on all the tested T0 transformants using real-time PCR. Further immunoprecipitation experiment using specific Oak1 antibodies confirmed the presence of Oak1 protein expression in the transformants. We report, for the first time, the generation of transgenic rice plants expressing Oak1 as a potential crop protection strategy against the golden apple snail pest.
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spelling upm-619492019-03-07T03:39:18Z http://psasir.upm.edu.my/id/eprint/61949/ Generation of transgenic rice expressing cyclotide precursor Oldenlandia affinis kalata B1 protein Lim, Yi Yi Lai, Kok Song Golden apple snail (Pomacea canaliculata) is a devastating pest on rice that causes heavy economic losses in South East Asia. In this study, we transformed mature seed-derived rice callus with plasmid containing Oldenlandia affinis kalata B1 (Oak1) gene encoding precursor's protein for potent molluscicidal agent of cyclotidekalata B1 targeting the golden apple snails. A total of 11 independent T0 transformants were recovered and 7 were positive Oak1transformants according to genomic PCR analysis. The Oak1 mRNA transcript was successfully detected on all the tested T0 transformants using real-time PCR. Further immunoprecipitation experiment using specific Oak1 antibodies confirmed the presence of Oak1 protein expression in the transformants. We report, for the first time, the generation of transgenic rice plants expressing Oak1 as a potential crop protection strategy against the golden apple snail pest. Pakistan Agricultural Scientists Forum 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/61949/1/Generation%20of%20transgenic%20rice%20expressing%20cyclotide%20precursor%20Oldenlandia%20affinis%20kalata%20B1%20protein.pdf Lim, Yi Yi and Lai, Kok Song (2017) Generation of transgenic rice expressing cyclotide precursor Oldenlandia affinis kalata B1 protein. The Journal of Animal and Plant Sciences, 27 (2). pp. 667-671. ISSN 1018-7081 https://www.cabi.org/agbiotechnet/abstract/20173193169
spellingShingle Lim, Yi Yi
Lai, Kok Song
Generation of transgenic rice expressing cyclotide precursor Oldenlandia affinis kalata B1 protein
title Generation of transgenic rice expressing cyclotide precursor Oldenlandia affinis kalata B1 protein
title_full Generation of transgenic rice expressing cyclotide precursor Oldenlandia affinis kalata B1 protein
title_fullStr Generation of transgenic rice expressing cyclotide precursor Oldenlandia affinis kalata B1 protein
title_full_unstemmed Generation of transgenic rice expressing cyclotide precursor Oldenlandia affinis kalata B1 protein
title_short Generation of transgenic rice expressing cyclotide precursor Oldenlandia affinis kalata B1 protein
title_sort generation of transgenic rice expressing cyclotide precursor oldenlandia affinis kalata b1 protein
url http://psasir.upm.edu.my/id/eprint/61949/
http://psasir.upm.edu.my/id/eprint/61949/
http://psasir.upm.edu.my/id/eprint/61949/1/Generation%20of%20transgenic%20rice%20expressing%20cyclotide%20precursor%20Oldenlandia%20affinis%20kalata%20B1%20protein.pdf