Extractive fermentation of lactic acid in lactic acid bacteria cultivation: a review
Lactic acid bacteria are industrially important microorganisms recognized for their fermentative ability mostly in their probiotic benefits as well as lactic acid production for various applications. Nevertheless, lactic acid fermentation often suffers end-product inhibition which decreases the cell...
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| Format: | Article |
| Language: | English |
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Frontiers Research Foundation
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/61832/ http://psasir.upm.edu.my/id/eprint/61832/1/Extractive%20fermentation%20of%20lactic%20acid.pdf |
| _version_ | 1848854499252240384 |
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| author | Othman, Majdiah Ariff, Arbakariya Rios-Solis, Leonardo Halim, Murni |
| author_facet | Othman, Majdiah Ariff, Arbakariya Rios-Solis, Leonardo Halim, Murni |
| author_sort | Othman, Majdiah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Lactic acid bacteria are industrially important microorganisms recognized for their fermentative ability mostly in their probiotic benefits as well as lactic acid production for various applications. Nevertheless, lactic acid fermentation often suffers end-product inhibition which decreases the cell growth rate. The inhibition of lactic acid is due to the solubility of the undissociated lactic acid within the cytoplasmic membrane and insolubility of dissociated lactate, which causes acidification of cytoplasm and failure of proton motive forces. This phenomenon influences the transmembrane pH gradient and decreases the amount of energy available for cell growth. In general, the restriction imposed by lactic acid on its fermentation can be avoided by extractive fermentation techniques, which can also be exploited for product recovery. |
| first_indexed | 2025-11-15T11:10:50Z |
| format | Article |
| id | upm-61832 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:10:50Z |
| publishDate | 2017 |
| publisher | Frontiers Research Foundation |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-618322019-02-19T07:55:40Z http://psasir.upm.edu.my/id/eprint/61832/ Extractive fermentation of lactic acid in lactic acid bacteria cultivation: a review Othman, Majdiah Ariff, Arbakariya Rios-Solis, Leonardo Halim, Murni Lactic acid bacteria are industrially important microorganisms recognized for their fermentative ability mostly in their probiotic benefits as well as lactic acid production for various applications. Nevertheless, lactic acid fermentation often suffers end-product inhibition which decreases the cell growth rate. The inhibition of lactic acid is due to the solubility of the undissociated lactic acid within the cytoplasmic membrane and insolubility of dissociated lactate, which causes acidification of cytoplasm and failure of proton motive forces. This phenomenon influences the transmembrane pH gradient and decreases the amount of energy available for cell growth. In general, the restriction imposed by lactic acid on its fermentation can be avoided by extractive fermentation techniques, which can also be exploited for product recovery. Frontiers Research Foundation 2017-11 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/61832/1/Extractive%20fermentation%20of%20lactic%20acid.pdf Othman, Majdiah and Ariff, Arbakariya and Rios-Solis, Leonardo and Halim, Murni (2017) Extractive fermentation of lactic acid in lactic acid bacteria cultivation: a review. Frontiers in Microbiology, 8. p. 43107. ISSN 1664-302X https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701932/ 10.3389/fmicb.2017.02285 |
| spellingShingle | Othman, Majdiah Ariff, Arbakariya Rios-Solis, Leonardo Halim, Murni Extractive fermentation of lactic acid in lactic acid bacteria cultivation: a review |
| title | Extractive fermentation of lactic acid in lactic acid bacteria cultivation: a review |
| title_full | Extractive fermentation of lactic acid in lactic acid bacteria cultivation: a review |
| title_fullStr | Extractive fermentation of lactic acid in lactic acid bacteria cultivation: a review |
| title_full_unstemmed | Extractive fermentation of lactic acid in lactic acid bacteria cultivation: a review |
| title_short | Extractive fermentation of lactic acid in lactic acid bacteria cultivation: a review |
| title_sort | extractive fermentation of lactic acid in lactic acid bacteria cultivation: a review |
| url | http://psasir.upm.edu.my/id/eprint/61832/ http://psasir.upm.edu.my/id/eprint/61832/ http://psasir.upm.edu.my/id/eprint/61832/ http://psasir.upm.edu.my/id/eprint/61832/1/Extractive%20fermentation%20of%20lactic%20acid.pdf |