Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique
An attractive electrochemical sensor of poly(3,4-ethylenedioxythiophene)/reduced graphene oxide electrode (PrGO) was developed for an electrochemical technique for uric acid (UA) detection in the presence of ascorbic acid (AA). PrGO composite film showed an improved electrocatalytic activity towards...
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| Format: | Article |
| Language: | English |
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Multidisciplinary Digital Publishing Institute
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/61448/ http://psasir.upm.edu.my/id/eprint/61448/1/Development%20of%20a%20PrGO.pdf |
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| author | Tukimin, Nurulkhalilah Abdullah, Jaafar Sulaiman, Yusran |
| author_facet | Tukimin, Nurulkhalilah Abdullah, Jaafar Sulaiman, Yusran |
| author_sort | Tukimin, Nurulkhalilah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | An attractive electrochemical sensor of poly(3,4-ethylenedioxythiophene)/reduced graphene oxide electrode (PrGO) was developed for an electrochemical technique for uric acid (UA) detection in the presence of ascorbic acid (AA). PrGO composite film showed an improved electrocatalytic activity towards UA oxidation in pH 6.0 (0.1 M PBS). The PrGO composite exhibited a high current signal and low charge transfer resistance (Rct) compared to a reduced graphene oxide (rGO) electrode or a bare glassy carbon electrode (GCE). The limit of detection and sensitivity of PrGO for the detection of UA are 0.19 μM (S/N = 3) and 0.01 μA/μM, respectively, in the range of 1–300 μM of UA. |
| first_indexed | 2025-11-15T11:09:28Z |
| format | Article |
| id | upm-61448 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:09:28Z |
| publishDate | 2017 |
| publisher | Multidisciplinary Digital Publishing Institute |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-614482018-10-09T07:52:00Z http://psasir.upm.edu.my/id/eprint/61448/ Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique Tukimin, Nurulkhalilah Abdullah, Jaafar Sulaiman, Yusran An attractive electrochemical sensor of poly(3,4-ethylenedioxythiophene)/reduced graphene oxide electrode (PrGO) was developed for an electrochemical technique for uric acid (UA) detection in the presence of ascorbic acid (AA). PrGO composite film showed an improved electrocatalytic activity towards UA oxidation in pH 6.0 (0.1 M PBS). The PrGO composite exhibited a high current signal and low charge transfer resistance (Rct) compared to a reduced graphene oxide (rGO) electrode or a bare glassy carbon electrode (GCE). The limit of detection and sensitivity of PrGO for the detection of UA are 0.19 μM (S/N = 3) and 0.01 μA/μM, respectively, in the range of 1–300 μM of UA. Multidisciplinary Digital Publishing Institute 2017-07 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/61448/1/Development%20of%20a%20PrGO.pdf Tukimin, Nurulkhalilah and Abdullah, Jaafar and Sulaiman, Yusran (2017) Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique. Sensors, 17 (7). pp. 1-12. ISSN 1424-8220 http://www.mdpi.com/1424-8220/17/7/1539 10.3390/s17071539 |
| spellingShingle | Tukimin, Nurulkhalilah Abdullah, Jaafar Sulaiman, Yusran Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique |
| title | Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique |
| title_full | Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique |
| title_fullStr | Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique |
| title_full_unstemmed | Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique |
| title_short | Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique |
| title_sort | development of a prgo-modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique |
| url | http://psasir.upm.edu.my/id/eprint/61448/ http://psasir.upm.edu.my/id/eprint/61448/ http://psasir.upm.edu.my/id/eprint/61448/ http://psasir.upm.edu.my/id/eprint/61448/1/Development%20of%20a%20PrGO.pdf |