Cerium oxide nanoparticles: green synthesis and biological applications

CeO2 nanoparticles (NPs) have shown promising approaches as therapeutic agents in biology and medical sciences. The physicochemical properties of CeO2-NPs, such as size, agglomeration status in liquid, and surface charge, play important roles in the ultimate interactions of the NP with target cells....

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Main Authors: Charbgoo, Fahimeh, Ahmad @ Ayob, Mansor, Darroudi, Majid
Format: Article
Language:English
Published: Dove Medical Press 2017
Online Access:http://psasir.upm.edu.my/id/eprint/61069/
http://psasir.upm.edu.my/id/eprint/61069/1/Cerium%20oxide%20nanoparticles%20green%20synthesis%20and%20biological%20applications.pdf
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author Charbgoo, Fahimeh
Ahmad @ Ayob, Mansor
Darroudi, Majid
author_facet Charbgoo, Fahimeh
Ahmad @ Ayob, Mansor
Darroudi, Majid
author_sort Charbgoo, Fahimeh
building UPM Institutional Repository
collection Online Access
description CeO2 nanoparticles (NPs) have shown promising approaches as therapeutic agents in biology and medical sciences. The physicochemical properties of CeO2-NPs, such as size, agglomeration status in liquid, and surface charge, play important roles in the ultimate interactions of the NP with target cells. Recently, CeO2-NPs have been synthesized through several bio-directed methods applying natural and organic matrices as stabilizing agents in order to prepare biocompatible CeO2-NPs, thereby solving the challenges regarding safety, and providing the appropriate situation for their effective use in biomedicine. This review discusses the different green strategies for CeO2-NPs synthesis, their advantages and challenges that are to be overcome. In addition, this review focuses on recent progress in the potential application of CeO2-NPs in biological and medical fields. Exploiting biocompatible CeO2-NPs may improve outcomes profoundly with the promise of effective neurodegenerative therapy and multiple applications in nanobiotechnology.
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spelling upm-610692018-09-24T06:54:12Z http://psasir.upm.edu.my/id/eprint/61069/ Cerium oxide nanoparticles: green synthesis and biological applications Charbgoo, Fahimeh Ahmad @ Ayob, Mansor Darroudi, Majid CeO2 nanoparticles (NPs) have shown promising approaches as therapeutic agents in biology and medical sciences. The physicochemical properties of CeO2-NPs, such as size, agglomeration status in liquid, and surface charge, play important roles in the ultimate interactions of the NP with target cells. Recently, CeO2-NPs have been synthesized through several bio-directed methods applying natural and organic matrices as stabilizing agents in order to prepare biocompatible CeO2-NPs, thereby solving the challenges regarding safety, and providing the appropriate situation for their effective use in biomedicine. This review discusses the different green strategies for CeO2-NPs synthesis, their advantages and challenges that are to be overcome. In addition, this review focuses on recent progress in the potential application of CeO2-NPs in biological and medical fields. Exploiting biocompatible CeO2-NPs may improve outcomes profoundly with the promise of effective neurodegenerative therapy and multiple applications in nanobiotechnology. Dove Medical Press 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/61069/1/Cerium%20oxide%20nanoparticles%20green%20synthesis%20and%20biological%20applications.pdf Charbgoo, Fahimeh and Ahmad @ Ayob, Mansor and Darroudi, Majid (2017) Cerium oxide nanoparticles: green synthesis and biological applications. International Journal of Nanomedicine, 12. pp. 1401-1413. ISSN 1176-9114; ESSN: 1178-2013 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325136/pdf/ijn-12-1401.pdf 10.2147/IJN.S124855
spellingShingle Charbgoo, Fahimeh
Ahmad @ Ayob, Mansor
Darroudi, Majid
Cerium oxide nanoparticles: green synthesis and biological applications
title Cerium oxide nanoparticles: green synthesis and biological applications
title_full Cerium oxide nanoparticles: green synthesis and biological applications
title_fullStr Cerium oxide nanoparticles: green synthesis and biological applications
title_full_unstemmed Cerium oxide nanoparticles: green synthesis and biological applications
title_short Cerium oxide nanoparticles: green synthesis and biological applications
title_sort cerium oxide nanoparticles: green synthesis and biological applications
url http://psasir.upm.edu.my/id/eprint/61069/
http://psasir.upm.edu.my/id/eprint/61069/
http://psasir.upm.edu.my/id/eprint/61069/
http://psasir.upm.edu.my/id/eprint/61069/1/Cerium%20oxide%20nanoparticles%20green%20synthesis%20and%20biological%20applications.pdf