Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia
Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes of the genus Leptospira. The aim of this study was to evaluate the susceptibility of isolates obtained from different hosts. A total of 65 Leptospira isolates from humans (n = 1), zoonoses (rat, n = 60; dog, n =...
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| Format: | Article |
| Language: | English |
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Medknow Publications
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/60888/ http://psasir.upm.edu.my/id/eprint/60888/1/Antimicrobial%20susceptibility%20of%20Leptospira%20spp.%20isolated%20from%20environmental%2C%20human%20and%20animal%20sources%20in%20Malaysia.pdf |
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| author | Benacer, Douadi Mohd Zain, Siti Nursheena Peck, Toung Ooi Kwai, Lin Thong |
| author_facet | Benacer, Douadi Mohd Zain, Siti Nursheena Peck, Toung Ooi Kwai, Lin Thong |
| author_sort | Benacer, Douadi |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes of the genus Leptospira. The aim of this study was to evaluate the susceptibility of isolates obtained from different hosts. A total of 65 Leptospira isolates from humans (n = 1), zoonoses (rat, n = 60; dog, n = 1; swine, n = 1) and environment (n = 2) were tested against six antibiotics. All the isolates were resistant to trimethoprim and sulphamethoxazole and had high MIC toward chloramphenicol (MIC90: 6.25 μg/ml). All except one environment isolate were sensitive to ampicillin, doxycycline and penicillin G. |
| first_indexed | 2025-11-15T11:07:33Z |
| format | Article |
| id | upm-60888 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:07:33Z |
| publishDate | 2017 |
| publisher | Medknow Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-608882019-04-29T08:06:45Z http://psasir.upm.edu.my/id/eprint/60888/ Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia Benacer, Douadi Mohd Zain, Siti Nursheena Peck, Toung Ooi Kwai, Lin Thong Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes of the genus Leptospira. The aim of this study was to evaluate the susceptibility of isolates obtained from different hosts. A total of 65 Leptospira isolates from humans (n = 1), zoonoses (rat, n = 60; dog, n = 1; swine, n = 1) and environment (n = 2) were tested against six antibiotics. All the isolates were resistant to trimethoprim and sulphamethoxazole and had high MIC toward chloramphenicol (MIC90: 6.25 μg/ml). All except one environment isolate were sensitive to ampicillin, doxycycline and penicillin G. Medknow Publications 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/60888/1/Antimicrobial%20susceptibility%20of%20Leptospira%20spp.%20isolated%20from%20environmental%2C%20human%20and%20animal%20sources%20in%20Malaysia.pdf Benacer, Douadi and Mohd Zain, Siti Nursheena and Peck, Toung Ooi and Kwai, Lin Thong (2017) Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia. Indian Journal of Medical Microbiology, 35 (1). pp. 124-128. ISSN 0255-0857; ESSN: 1998-3646 http://eprints.um.edu.my/18382/1/Antimicrobial_Susceptibility_of_Leptospira_spp._Isolated_from.pdf 10.4103/ijmm.IJMM_15_458 |
| spellingShingle | Benacer, Douadi Mohd Zain, Siti Nursheena Peck, Toung Ooi Kwai, Lin Thong Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia |
| title | Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia |
| title_full | Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia |
| title_fullStr | Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia |
| title_full_unstemmed | Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia |
| title_short | Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia |
| title_sort | antimicrobial susceptibility of leptospira spp. isolated from environmental, human and animal sources in malaysia |
| url | http://psasir.upm.edu.my/id/eprint/60888/ http://psasir.upm.edu.my/id/eprint/60888/ http://psasir.upm.edu.my/id/eprint/60888/ http://psasir.upm.edu.my/id/eprint/60888/1/Antimicrobial%20susceptibility%20of%20Leptospira%20spp.%20isolated%20from%20environmental%2C%20human%20and%20animal%20sources%20in%20Malaysia.pdf |