Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats
Objective: Increased consumption of fruits and vegetables as functional foods leads to the reduction of signs of metabolic syndrome. The aim of this study was to measure and compare cardiovascular, liver, and metabolic parameters following chronic administration of the same dose of anthocyanins eith...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/60873/ http://psasir.upm.edu.my/id/eprint/60873/1/Anthocyanins%20in%20chokeberry%20and%20purple%20maize%20attenuate%20diet-induced%20metabolic%20syndrome%20in%20rats.pdf |
| _version_ | 1848854289467834368 |
|---|---|
| author | Bhaswant, Maharshi Shafie, Siti Raihanah Mathai, Michael L. Mouatt, Peter Brown, Lindsay |
| author_facet | Bhaswant, Maharshi Shafie, Siti Raihanah Mathai, Michael L. Mouatt, Peter Brown, Lindsay |
| author_sort | Bhaswant, Maharshi |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Objective: Increased consumption of fruits and vegetables as functional foods leads to the reduction of signs of metabolic syndrome. The aim of this study was to measure and compare cardiovascular, liver, and metabolic parameters following chronic administration of the same dose of anthocyanins either from chokeberry (CB) or purple maize (PM) in rats with diet-induced metabolic syndrome. Methods: Male Wistar rats were fed a maize starch (C) or high-carbohydrate, high-fat diet (H) and divided into six groups for 16 wk. The rats were fed C, C with CB or PM for the last 8 wk (CCB or CPM), H, H with CB or PM for the last 8 wk (HCB or HPM); CB and PM rats received ∼8 mg anthocyanins/kg daily. The rats were monitored for changes in blood pressure, cardiovascular and hepatic structure and function, glucose tolerance, and adipose tissue mass. Results: HCB and HPM rats showed reduced visceral adiposity index, total body fat mass, and systolic blood pressure; improved glucose tolerance, liver, and cardiovascular structure and function; decreased plasma triacylglycerols and total cholesterol compared with H rats. Inflammatory cell infiltration was reduced in heart and liver. Conclusion: CB and PM interventions gave similar responses, suggesting that anthocyanins are the bioactive molecules in the attenuation or reversal of metabolic syndrome by prevention of inflammation-induced damage. |
| first_indexed | 2025-11-15T11:07:30Z |
| format | Article |
| id | upm-60873 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:07:30Z |
| publishDate | 2017 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-608732019-03-25T10:08:24Z http://psasir.upm.edu.my/id/eprint/60873/ Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats Bhaswant, Maharshi Shafie, Siti Raihanah Mathai, Michael L. Mouatt, Peter Brown, Lindsay Objective: Increased consumption of fruits and vegetables as functional foods leads to the reduction of signs of metabolic syndrome. The aim of this study was to measure and compare cardiovascular, liver, and metabolic parameters following chronic administration of the same dose of anthocyanins either from chokeberry (CB) or purple maize (PM) in rats with diet-induced metabolic syndrome. Methods: Male Wistar rats were fed a maize starch (C) or high-carbohydrate, high-fat diet (H) and divided into six groups for 16 wk. The rats were fed C, C with CB or PM for the last 8 wk (CCB or CPM), H, H with CB or PM for the last 8 wk (HCB or HPM); CB and PM rats received ∼8 mg anthocyanins/kg daily. The rats were monitored for changes in blood pressure, cardiovascular and hepatic structure and function, glucose tolerance, and adipose tissue mass. Results: HCB and HPM rats showed reduced visceral adiposity index, total body fat mass, and systolic blood pressure; improved glucose tolerance, liver, and cardiovascular structure and function; decreased plasma triacylglycerols and total cholesterol compared with H rats. Inflammatory cell infiltration was reduced in heart and liver. Conclusion: CB and PM interventions gave similar responses, suggesting that anthocyanins are the bioactive molecules in the attenuation or reversal of metabolic syndrome by prevention of inflammation-induced damage. Elsevier 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/60873/1/Anthocyanins%20in%20chokeberry%20and%20purple%20maize%20attenuate%20diet-induced%20metabolic%20syndrome%20in%20rats.pdf Bhaswant, Maharshi and Shafie, Siti Raihanah and Mathai, Michael L. and Mouatt, Peter and Brown, Lindsay (2017) Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats. Nutrition, 41. 24 - 31. ISSN 0899-9007; ESSN: 1873-1244 https://reader.elsevier.com/reader/sd/pii/S0899900716302830?token=D225FB86B2772441B36EF7BDBE927526D9036D75739A3427E8815ED9795835100DE4D9BC7202144FBCFEF694894E7500 10.1016/j.nut.2016.12.009 |
| spellingShingle | Bhaswant, Maharshi Shafie, Siti Raihanah Mathai, Michael L. Mouatt, Peter Brown, Lindsay Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats |
| title | Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats |
| title_full | Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats |
| title_fullStr | Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats |
| title_full_unstemmed | Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats |
| title_short | Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats |
| title_sort | anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats |
| url | http://psasir.upm.edu.my/id/eprint/60873/ http://psasir.upm.edu.my/id/eprint/60873/ http://psasir.upm.edu.my/id/eprint/60873/ http://psasir.upm.edu.my/id/eprint/60873/1/Anthocyanins%20in%20chokeberry%20and%20purple%20maize%20attenuate%20diet-induced%20metabolic%20syndrome%20in%20rats.pdf |