An improved parallelized mRMR for gene subset selection in cancer classification

DNA microarray technique has become a more attractive tool for cancer classification in the scientific and industrial fields. Based on the previous researchers, the conventional approach for cancer classification is primarily based on morphological appearance of the tumor. The limitations of this ap...

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Main Authors: Mohammad Kusairi, Rohani, Moorthy, Kohbalan, Haron, Habibollah, Mohamad, Mohd Saberi, Napis, Suhaimi, Kasim, Shahreen
Format: Article
Language:English
Published: Indonesian Society for Knowledge and Human Development 2017
Online Access:http://psasir.upm.edu.my/id/eprint/60822/
http://psasir.upm.edu.my/id/eprint/60822/1/An%20improved%20parallelized%20mRMR%20for%20gene%20subset%20selection%20in%20cancer%20classification.pdf
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author Mohammad Kusairi, Rohani
Moorthy, Kohbalan
Haron, Habibollah
Mohamad, Mohd Saberi
Napis, Suhaimi
Kasim, Shahreen
author_facet Mohammad Kusairi, Rohani
Moorthy, Kohbalan
Haron, Habibollah
Mohamad, Mohd Saberi
Napis, Suhaimi
Kasim, Shahreen
author_sort Mohammad Kusairi, Rohani
building UPM Institutional Repository
collection Online Access
description DNA microarray technique has become a more attractive tool for cancer classification in the scientific and industrial fields. Based on the previous researchers, the conventional approach for cancer classification is primarily based on morphological appearance of the tumor. The limitations of this approach are bias in identify the tumors by expert and faced the difficulty in differentiate the cancer subtypes due to most cancers being highly related to the specific biological insight. Thus, this study propose an improved parallelized Minimum Redundancy Maximum Relevance (mRMR), which is a particularly fast feature selection method for finding a set of both relevant and complementary features. The mRMR can identify genes more relevance to biological context that leads to richer biological interpretations. The proposed method is expected to achieve accurate classification performance using small number of predictive genes when tested using two datasets from Cancer Genome Project and compared to previous methods.
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institution Universiti Putra Malaysia
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language English
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publishDate 2017
publisher Indonesian Society for Knowledge and Human Development
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spelling upm-608222019-03-26T09:28:26Z http://psasir.upm.edu.my/id/eprint/60822/ An improved parallelized mRMR for gene subset selection in cancer classification Mohammad Kusairi, Rohani Moorthy, Kohbalan Haron, Habibollah Mohamad, Mohd Saberi Napis, Suhaimi Kasim, Shahreen DNA microarray technique has become a more attractive tool for cancer classification in the scientific and industrial fields. Based on the previous researchers, the conventional approach for cancer classification is primarily based on morphological appearance of the tumor. The limitations of this approach are bias in identify the tumors by expert and faced the difficulty in differentiate the cancer subtypes due to most cancers being highly related to the specific biological insight. Thus, this study propose an improved parallelized Minimum Redundancy Maximum Relevance (mRMR), which is a particularly fast feature selection method for finding a set of both relevant and complementary features. The mRMR can identify genes more relevance to biological context that leads to richer biological interpretations. The proposed method is expected to achieve accurate classification performance using small number of predictive genes when tested using two datasets from Cancer Genome Project and compared to previous methods. Indonesian Society for Knowledge and Human Development 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/60822/1/An%20improved%20parallelized%20mRMR%20for%20gene%20subset%20selection%20in%20cancer%20classification.pdf Mohammad Kusairi, Rohani and Moorthy, Kohbalan and Haron, Habibollah and Mohamad, Mohd Saberi and Napis, Suhaimi and Kasim, Shahreen (2017) An improved parallelized mRMR for gene subset selection in cancer classification. International Journal on Advanced Science, Engineering and Information Technology, 7 (4-2). 1595 - 1600. ISSN 2088-5334; ESSN: 2460-6952 10.18517/ijaseit.7.4-2.3395
spellingShingle Mohammad Kusairi, Rohani
Moorthy, Kohbalan
Haron, Habibollah
Mohamad, Mohd Saberi
Napis, Suhaimi
Kasim, Shahreen
An improved parallelized mRMR for gene subset selection in cancer classification
title An improved parallelized mRMR for gene subset selection in cancer classification
title_full An improved parallelized mRMR for gene subset selection in cancer classification
title_fullStr An improved parallelized mRMR for gene subset selection in cancer classification
title_full_unstemmed An improved parallelized mRMR for gene subset selection in cancer classification
title_short An improved parallelized mRMR for gene subset selection in cancer classification
title_sort improved parallelized mrmr for gene subset selection in cancer classification
url http://psasir.upm.edu.my/id/eprint/60822/
http://psasir.upm.edu.my/id/eprint/60822/
http://psasir.upm.edu.my/id/eprint/60822/1/An%20improved%20parallelized%20mRMR%20for%20gene%20subset%20selection%20in%20cancer%20classification.pdf