A simple add-and display method for immobilisation of cancer drug on his-tagged virus-like nanoparticles for controlled drug delivery

A simple add-and display method for immobilisation of cancer drug on his-tagged virus-like nanoparticles for controlled drug delivery

pH-responsive virus-like nanoparticles (VLNPs) hold promising potential as drug delivery systems for cancer therapy. In the present study, hepatitis B virus (HBV) VLNPs harbouring His-tags were used to display doxorubicin (DOX) via nitrilotriacetic acid (NTA) conjugation. The His-tags served as pH-r...

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Bibliographic Details
Main Authors: Biabanikhankahdani, Roya, Bayat, Saadi, Ho, Kok Lian, Mohammed Alitheen, Noorjahan Banu, Tan, Wen Siang
Format: Article
Language:English
Published: Nature Publishing Group 2017
Online Access:http://psasir.upm.edu.my/id/eprint/60732/
http://psasir.upm.edu.my/id/eprint/60732/1/A%20simple%20add-and%20display%20method%20for%20immobilisation%20of%20cancer%20drug%20on%20his-tagged%20virus-like%20nanoparticles%20for%20controlled%20drug%20delivery.pdf

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