A review on the effects of prebiotics on cell toxicity and integrity
Prebiotics are known as the ‘food’ for beneficial gut microbiota that are capable of promoting host health. Their effects depend on the product of gut fermentation or metabolites. This paper discusses the role of prebiotics on cytotoxicity, genotoxicity, and cell integrity. Metabolites produced from...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/60725/ http://psasir.upm.edu.my/id/eprint/60725/1/A%20review%20on%20the%20effects%20of%20prebiotics%20on%20cell%20toxicity%20and%20integrity.pdf |
| _version_ | 1848854260050034688 |
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| author | Mundi, Morven Mikal, Kathleen Michelle Ahmed, Osumanu Haruna Sarbini, Shahrul Razid |
| author_facet | Mundi, Morven Mikal, Kathleen Michelle Ahmed, Osumanu Haruna Sarbini, Shahrul Razid |
| author_sort | Mundi, Morven |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Prebiotics are known as the ‘food’ for beneficial gut microbiota that are capable of promoting host health. Their effects depend on the product of gut fermentation or metabolites. This paper discusses the role of prebiotics on cytotoxicity, genotoxicity, and cell integrity. Metabolites produced from the fermentation of prebiotics can be used to understand gut diseases such as colorectal cancer. Fecal water from in vivo or in vitro studies can be used to understand the relationship between prebiotics and gut diseases because of its close contact with colon epithelium. Besides, fecal water has compounds that are capable of modifying colonocytes. |
| first_indexed | 2025-11-15T11:07:02Z |
| format | Article |
| id | upm-60725 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:07:02Z |
| publishDate | 2017 |
| publisher | Taylor & Francis |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-607252019-04-29T05:28:57Z http://psasir.upm.edu.my/id/eprint/60725/ A review on the effects of prebiotics on cell toxicity and integrity Mundi, Morven Mikal, Kathleen Michelle Ahmed, Osumanu Haruna Sarbini, Shahrul Razid Prebiotics are known as the ‘food’ for beneficial gut microbiota that are capable of promoting host health. Their effects depend on the product of gut fermentation or metabolites. This paper discusses the role of prebiotics on cytotoxicity, genotoxicity, and cell integrity. Metabolites produced from the fermentation of prebiotics can be used to understand gut diseases such as colorectal cancer. Fecal water from in vivo or in vitro studies can be used to understand the relationship between prebiotics and gut diseases because of its close contact with colon epithelium. Besides, fecal water has compounds that are capable of modifying colonocytes. Taylor & Francis 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/60725/1/A%20review%20on%20the%20effects%20of%20prebiotics%20on%20cell%20toxicity%20and%20integrity.pdf Mundi, Morven and Mikal, Kathleen Michelle and Ahmed, Osumanu Haruna and Sarbini, Shahrul Razid (2017) A review on the effects of prebiotics on cell toxicity and integrity. International Journal of Food Properties, 20 (supp. 1). pp. 1-8. ISSN 1094-2912; ESSN: 1532-2386 https://www.tandfonline.com/doi/pdf/10.1080/10942912.2017.1326937?needAccess=true 10.1080/10942912.2017.1326937 |
| spellingShingle | Mundi, Morven Mikal, Kathleen Michelle Ahmed, Osumanu Haruna Sarbini, Shahrul Razid A review on the effects of prebiotics on cell toxicity and integrity |
| title | A review on the effects of prebiotics on cell toxicity and integrity |
| title_full | A review on the effects of prebiotics on cell toxicity and integrity |
| title_fullStr | A review on the effects of prebiotics on cell toxicity and integrity |
| title_full_unstemmed | A review on the effects of prebiotics on cell toxicity and integrity |
| title_short | A review on the effects of prebiotics on cell toxicity and integrity |
| title_sort | review on the effects of prebiotics on cell toxicity and integrity |
| url | http://psasir.upm.edu.my/id/eprint/60725/ http://psasir.upm.edu.my/id/eprint/60725/ http://psasir.upm.edu.my/id/eprint/60725/ http://psasir.upm.edu.my/id/eprint/60725/1/A%20review%20on%20the%20effects%20of%20prebiotics%20on%20cell%20toxicity%20and%20integrity.pdf |