A rare case of vein of galen thrombosis: exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis
Cerebral deep vein thrombosis is rare but it carries high morbidity and mortality. The mainstay of treatment is anticoagulation with vitamin K antagonist (VKA). However, VKA has a lot of drawback of fatal bleeding in Asian population, drug-drug and drug-food interactions and the need for frequent IN...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Pakistan Medical Association Rawalpindi Islamabad Branch
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/60703/ http://psasir.upm.edu.my/id/eprint/60703/1/A%20rare%20case%20of%20vein%20of%20galen%20thrombosis%20exploring%20a%20potential%20role%20for%20novel%20oral%20anticoagulants%20%28NOACs%29%20in%20cerebral%20deep%20vein%20thrombosis.pdf |
| _version_ | 1848854254106705920 |
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| author | Inche Mat, Liyana Najwa Wan Sulaiman, Wan Aliaa Hoo, Fan Kee Mohammad Sallehuddin, Hakimah Basri, Hamidon |
| author_facet | Inche Mat, Liyana Najwa Wan Sulaiman, Wan Aliaa Hoo, Fan Kee Mohammad Sallehuddin, Hakimah Basri, Hamidon |
| author_sort | Inche Mat, Liyana Najwa |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Cerebral deep vein thrombosis is rare but it carries high morbidity and mortality. The mainstay of treatment is anticoagulation with vitamin K antagonist (VKA). However, VKA has a lot of drawback of fatal bleeding in Asian population, drug-drug and drug-food interactions and the need for frequent INR monitoring when compared to novel oral anticoagulants (NOACs). Here, we present a case of a 52-year-old lady who was admitted with 3 days history of a headache and confusion. Physical examinations revealed no long tract signs and blood investigations were normal. Thrombosis of the vein of Galen was diagnosed on MRI of the brain. We describe successful treatment with subcutaneous low molecular weight heparin for 2 weeks followed by oral direct thrombin inhibitor dabigatran. |
| first_indexed | 2025-11-15T11:06:56Z |
| format | Article |
| id | upm-60703 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:06:56Z |
| publishDate | 2017 |
| publisher | Pakistan Medical Association Rawalpindi Islamabad Branch |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-607032018-05-17T03:29:54Z http://psasir.upm.edu.my/id/eprint/60703/ A rare case of vein of galen thrombosis: exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis Inche Mat, Liyana Najwa Wan Sulaiman, Wan Aliaa Hoo, Fan Kee Mohammad Sallehuddin, Hakimah Basri, Hamidon Cerebral deep vein thrombosis is rare but it carries high morbidity and mortality. The mainstay of treatment is anticoagulation with vitamin K antagonist (VKA). However, VKA has a lot of drawback of fatal bleeding in Asian population, drug-drug and drug-food interactions and the need for frequent INR monitoring when compared to novel oral anticoagulants (NOACs). Here, we present a case of a 52-year-old lady who was admitted with 3 days history of a headache and confusion. Physical examinations revealed no long tract signs and blood investigations were normal. Thrombosis of the vein of Galen was diagnosed on MRI of the brain. We describe successful treatment with subcutaneous low molecular weight heparin for 2 weeks followed by oral direct thrombin inhibitor dabigatran. Pakistan Medical Association Rawalpindi Islamabad Branch 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/60703/1/A%20rare%20case%20of%20vein%20of%20galen%20thrombosis%20exploring%20a%20potential%20role%20for%20novel%20oral%20anticoagulants%20%28NOACs%29%20in%20cerebral%20deep%20vein%20thrombosis.pdf Inche Mat, Liyana Najwa and Wan Sulaiman, Wan Aliaa and Hoo, Fan Kee and Mohammad Sallehuddin, Hakimah and Basri, Hamidon (2017) A rare case of vein of galen thrombosis: exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis. Rawal Medical Journal, 42 (3). 432 - 434. ISSN 0303-5212 |
| spellingShingle | Inche Mat, Liyana Najwa Wan Sulaiman, Wan Aliaa Hoo, Fan Kee Mohammad Sallehuddin, Hakimah Basri, Hamidon A rare case of vein of galen thrombosis: exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis |
| title | A rare case of vein of galen thrombosis: exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis |
| title_full | A rare case of vein of galen thrombosis: exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis |
| title_fullStr | A rare case of vein of galen thrombosis: exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis |
| title_full_unstemmed | A rare case of vein of galen thrombosis: exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis |
| title_short | A rare case of vein of galen thrombosis: exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis |
| title_sort | rare case of vein of galen thrombosis: exploring a potential role for novel oral anticoagulants (noacs) in cerebral deep vein thrombosis |
| url | http://psasir.upm.edu.my/id/eprint/60703/ http://psasir.upm.edu.my/id/eprint/60703/1/A%20rare%20case%20of%20vein%20of%20galen%20thrombosis%20exploring%20a%20potential%20role%20for%20novel%20oral%20anticoagulants%20%28NOACs%29%20in%20cerebral%20deep%20vein%20thrombosis.pdf |