Muntingia calabura: a review of its traditional uses, chemical properties, and pharmacological observations

Context: Different parts of Muntingia calabura L. (Elaeocarpaceae), or “kerukup siam” in Malay, have been reported to possess medicinal value, supported by a number of scientific studies. Materials and methods: Literature has been retrieved from a number of databases (e.g., Pubmed, Science Direct,...

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Main Authors: Mahmood, Nur Diyana, Md Nasir, Nur Liana, Rofiee, Mohd Salleh, Md Tohid, Siti Farah, Ching, Siew Mooi, Teh, Lay Kek, Salleh, Mohd Zaki, Zakaria, Zainul Amiruddin
Format: Article
Language:English
Published: Informa Healthcare 2014
Online Access:http://psasir.upm.edu.my/id/eprint/60577/
http://psasir.upm.edu.my/id/eprint/60577/1/Muntingia%20calabura%20a%20review%20of%20its%20traditional%20uses%2C%20chemical%20properties%2C%20and%20pharmacological%20observations.pdf
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author Mahmood, Nur Diyana
Md Nasir, Nur Liana
Rofiee, Mohd Salleh
Md Tohid, Siti Farah
Ching, Siew Mooi
Teh, Lay Kek
Salleh, Mohd Zaki
Zakaria, Zainul Amiruddin
author_facet Mahmood, Nur Diyana
Md Nasir, Nur Liana
Rofiee, Mohd Salleh
Md Tohid, Siti Farah
Ching, Siew Mooi
Teh, Lay Kek
Salleh, Mohd Zaki
Zakaria, Zainul Amiruddin
author_sort Mahmood, Nur Diyana
building UPM Institutional Repository
collection Online Access
description Context: Different parts of Muntingia calabura L. (Elaeocarpaceae), or “kerukup siam” in Malay, have been reported to possess medicinal value, supported by a number of scientific studies. Materials and methods: Literature has been retrieved from a number of databases (e.g., Pubmed, Science Direct, Springer Link, etc.). General web searches were also carried out using Google and Yahoo search engines by applying some related search terms (e.g., Muntingia calabura, phytochemical, pharmacological, extract, and traditional uses). The articles related to agriculture, ecology, and synthetic work and those using languages other than English or Malay have been excluded. The bibliographies of papers relating to the review subject were also searched for further relevant references. Results and discussion: The literature search conducted using the above-mentioned Internet search engines only lead to the identification of 36 journals published as early as 1987. From the articles reviewed, M. calabura possessed various pharmacological activities (e.g., cytotoxic, antinociceptive, antiulcer, anti-inflammatory), which supported the folklore claims and could be attributed to its phytoconstituents. Conclusion: Muntingia calabura possesses remarkable medicinal value, which warrants further and in-depth studies. Therefore, this review paper is presented to help guide researchers to plan their future studies related to this plant in the hope of isolating potential leads for future drug development.
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spelling upm-605772018-06-07T08:42:07Z http://psasir.upm.edu.my/id/eprint/60577/ Muntingia calabura: a review of its traditional uses, chemical properties, and pharmacological observations Mahmood, Nur Diyana Md Nasir, Nur Liana Rofiee, Mohd Salleh Md Tohid, Siti Farah Ching, Siew Mooi Teh, Lay Kek Salleh, Mohd Zaki Zakaria, Zainul Amiruddin Context: Different parts of Muntingia calabura L. (Elaeocarpaceae), or “kerukup siam” in Malay, have been reported to possess medicinal value, supported by a number of scientific studies. Materials and methods: Literature has been retrieved from a number of databases (e.g., Pubmed, Science Direct, Springer Link, etc.). General web searches were also carried out using Google and Yahoo search engines by applying some related search terms (e.g., Muntingia calabura, phytochemical, pharmacological, extract, and traditional uses). The articles related to agriculture, ecology, and synthetic work and those using languages other than English or Malay have been excluded. The bibliographies of papers relating to the review subject were also searched for further relevant references. Results and discussion: The literature search conducted using the above-mentioned Internet search engines only lead to the identification of 36 journals published as early as 1987. From the articles reviewed, M. calabura possessed various pharmacological activities (e.g., cytotoxic, antinociceptive, antiulcer, anti-inflammatory), which supported the folklore claims and could be attributed to its phytoconstituents. Conclusion: Muntingia calabura possesses remarkable medicinal value, which warrants further and in-depth studies. Therefore, this review paper is presented to help guide researchers to plan their future studies related to this plant in the hope of isolating potential leads for future drug development. Informa Healthcare 2014 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/60577/1/Muntingia%20calabura%20a%20review%20of%20its%20traditional%20uses%2C%20chemical%20properties%2C%20and%20pharmacological%20observations.pdf Mahmood, Nur Diyana and Md Nasir, Nur Liana and Rofiee, Mohd Salleh and Md Tohid, Siti Farah and Ching, Siew Mooi and Teh, Lay Kek and Salleh, Mohd Zaki and Zakaria, Zainul Amiruddin (2014) Muntingia calabura: a review of its traditional uses, chemical properties, and pharmacological observations. Pharmaceutical Biology, 52 (12). pp. 1598-1623. ISSN 1388-0209; ESSN: 1744-5116 https://www.tandfonline.com/doi/full/10.3109/13880209.2014.908397 10.3109/13880209.2014.908397
spellingShingle Mahmood, Nur Diyana
Md Nasir, Nur Liana
Rofiee, Mohd Salleh
Md Tohid, Siti Farah
Ching, Siew Mooi
Teh, Lay Kek
Salleh, Mohd Zaki
Zakaria, Zainul Amiruddin
Muntingia calabura: a review of its traditional uses, chemical properties, and pharmacological observations
title Muntingia calabura: a review of its traditional uses, chemical properties, and pharmacological observations
title_full Muntingia calabura: a review of its traditional uses, chemical properties, and pharmacological observations
title_fullStr Muntingia calabura: a review of its traditional uses, chemical properties, and pharmacological observations
title_full_unstemmed Muntingia calabura: a review of its traditional uses, chemical properties, and pharmacological observations
title_short Muntingia calabura: a review of its traditional uses, chemical properties, and pharmacological observations
title_sort muntingia calabura: a review of its traditional uses, chemical properties, and pharmacological observations
url http://psasir.upm.edu.my/id/eprint/60577/
http://psasir.upm.edu.my/id/eprint/60577/
http://psasir.upm.edu.my/id/eprint/60577/
http://psasir.upm.edu.my/id/eprint/60577/1/Muntingia%20calabura%20a%20review%20of%20its%20traditional%20uses%2C%20chemical%20properties%2C%20and%20pharmacological%20observations.pdf